Adam Zweifach
Professor/Molecular and Cell Biology

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Scholarly Contributions

25 Scholarly Contributions

18
Journal Articles
6
Poster/Presentations
1
Book Chapter
Calcineurin activation is only one calcium-dependent step in cytotoxic T lymphocyte granule exocytosis.
2007
M J Grybko, G A Wurth, J P Bartnik, Adam Zweifach, A T Pores-Fernando
Research Type: Journal Article

Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role.
2007
Adam Zweifach, A T Pores-Fernando, G A Wurth, M J Grybko
Research Type: Journal Article

ERK activation is only one role of PKC in TCR-independent cytotoxic T cell granule exocytosis.
2008
M J Grybko, S Gaur, Adam Zweifach, A T Pores-Fernando
Research Type: Journal Article

Calcium influx and signaling in cytotoxic T-lymphocyte lytic granule exocytosis.
2009
A T Pores-Fernando, Adam Zweifach
Research Type: Journal Article

Calcineurin-dependent lytic granule exocytosis in NK-92 natural killer cells.
2009
S Gaur, Adam Zweifach, A T Pores-Fernando, M Y Doyon
Research Type: Journal Article

No specific subcellular localization of protein kinase C is required for cytotoxic T cell granule exocytosis.
2009
M Y Ranaghan, A T Pores-Fernando, Adam Zweifach
Research Type: Journal Article

Novel high throughput assays for cytotoxic T lymphocyte function based on flow cytometry.
2014
Adam Zweifach
Research Type: Poster/Presentation

A High Throughput Phenotypic Screen of Cytotoxic T Lymphocyte Lytic Granule Exocytosis Reveals Candidate Immunosuppressants
2015
Larry A Sklar, Ziyan Zhao, Adam Zweifach, Oleg Ursu, Mark K Haynes, Bruce S Edwards
Research Type: Journal Article

Flow Cytometry Enables Multiplexed Measurements of Genetically Encoded Intramolecular FRET Sensors Suitable for Screening.
2016
J Doucette, Z Zhao, M M Barra, Adam Zweifach, Marcy J Balunas, R J Geyer
Research Type: Journal Article

Development of an Enhanced Phenotypic Screen of Cytotoxic T-Lymphocyte Lytic Granule Exocytosis Suitable for Use with Synthetic Compound and Natural Product Collections.
2016
J A deMayo, Marcy J Balunas, Adam Zweifach, Z Zhao, A M West
Research Type: Journal Article

Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity.
2016
J Li, Marcy J Balunas, Andrew Wiemer, S M Gromek, A T Maxwell, C M Pavlik, A M West, Adam Zweifach, Z Zhao, J A deMayo
Research Type: Journal Article

Metallothionein regulates intracellular zinc signaling during CD4(+) T cell activation.
2016
Michael A Lynes, Adam Zweifach, J M Rice
Research Type: Journal Article

Flow cytometry enables multiplexed measurements of genetically-encoded sensors based on intramolecular Förster resonance energy transfer.
2016
Adam Zweifach
Research Type: Poster/Presentation

A novel ensemble approach to providing small molecule support for validation of cellular targets confirms that glycolysis is a viable antiproliferative strategy in leukemic cells.
2017
Adam Zweifach
Research Type: Poster/Presentation

A novel ensemble approach to providing small molecule support for validation of cellular targets confirms that glycolysis inhibition is a viable antiproliferative strategy in leukemic cells
2017
Adam Zweifach
Research Type: Poster/Presentation

A Multiplexed Assay That Monitors Effects of Multiple Compound Treatment Times Reveals Candidate Immune-Enhancing Compounds.
2018
Z Zhao, Adam Zweifach, L Henowitz
Research Type: Journal Article

A Novel Multiple-Read Screen for Metabolically Active Compounds Based on a Genetically Encoded FRET Sensor for ATP.
2018
R Rajagopalan, Adam Zweifach, Z Zhao
Research Type: Journal Article

Post-Glycosylation Diversification (PGD): An Approach for Assembling Collections of Glycosylated Small Molecules
2019
Adam Zweifach, Dennis Wright, Chris Lorenc, Santosh Keshipeddy, Victoria L. Robinson, Ala M. Shaqra, Liza Henowitz, Zachary Cannone, Mark W Peczuh
Research Type: Journal Article

Temperature-Dependent Expression of a CFP-YFP FRET Diacylglycerol Sensor Enables Multiple-Read Screening for Compounds That Affect C1 Domains.
2019
Xiusheng Yang, Adam Zweifach
Research Type: Journal Article

Journeying with Cytotoxic T lymphocytes from Signaling to Phenotypic Screening: and some lessons learned along the way
2019
Adam Zweifach
Research Type: Poster/Presentation