Amy R. Howell
Professor/Chemistry

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1,4-Dicarbofunctionalization of 4-Fluoroaryl Grignard and Lithium Reagents with Disubstituted Malononitriles.
2017
C A Busacca, I K Luvaga, I Volchkov, Amy R Howell, C H Senanayake, C A Malapit, J T Reeves
Research Type: Journal Article

4-Oxaspiro[2.3]hexanes: A Novel Platinum(II) Catalyzed Transformation
2011
Meena Thakur, Rosa Taboada, Amy R Howell, Sampada Chitale
Research Type: Poster/Presentation

A 2-methyleneoxetane analog of orlistat demonstrating inhibition of porcine pancreatic lipase.
1998
Amy R Howell, L M Dollinger
Research Type: Journal Article

A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity.
2010
X Li, S B Wilson, P Stock, Amy R Howell, K O Yu, T Shiratsuchi, J Kerzerho, W Yang, O Akbari, M Kronenberg, V Lombardi, B A Sullivan, S A Porcelli, M Tsuji, A K Singh, N E Hnatiuk
Research Type: Journal Article

A Solvent-free Approach to Glycosyl Amides: Towards the Synthesis of α-N-Galactosyl Ceramides.
2015
Amy R Howell, D Chennamadhavuni
Research Type: Journal Article

A Versatile Preparation of 2-Methyleneoxetanes.
1996
L M Dollinger, Amy R Howell
Research Type: Journal Article

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR.
2008
Stewart Richardson, R Koh, T Beddoe, D I Godfrey, Amy R Howell, M Thakur, L Kjer-Nielsen, L Gapin, J P Scott-Browne, J Rossjohn, K S Wun, N A Borg, J McCluskey
Research Type: Journal Article

A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells.
2011
M S Thakur, D G Pellicci, S Keshipeddy, A G Brooks, A P Uldrich, O Patel, S A Porcelli, K S Wun, Amy R Howell, D I Godfrey, G S Besra, G Cameron, Stewart Richardson, P A Illarionov, J McCluskey, J Rossjohn, S S Pang, M H Young, L Gapin, L C Sullivan
Research Type: Journal Article

A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids.
2011
S K Chung, P Arora, J H Lee, G Bricard, M M Venkataswamy, A Baena, Q Li, S A Porcelli, K C Seo, N Veerapen, P A Illarionov, R Ndonye, J J Park, Amy R Howell, G S Besra, Y T Chang
Research Type: Journal Article

Access to Oxetane-containing psico-Nucleosides from 2-Methyleneoxetanes: A Role for Neighboring Group Participation?
2011
Paul R Rablen, Bryan T Whiting, John M Rowley, Yanke Liang, Martha M Morton, Nathan Hnatiuk, Geoffrey W Coates, Amy R Howell
Research Type: Journal Article

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.
2009
Amy R Howell, P G Wang, D G Pellicci, C Xia, Y Zhang, J McCluskey, Y Kinjo, O Patel, W Chen, L Kjer-Nielsen, D M Zajonc, D I Godfrey, Stewart Richardson, W C Florence, L E Gordy, J Scott-Browne, K O Yu, L Gapin, J Rossjohn, S Joyce, K Hayakawa, S A Porcelli, S Keshipeddy
Research Type: Journal Article

Alpha-S-GalCer: synthesis and evaluation for iNKT cell stimulation.
2008
J Paulsen, M L Blauvelt, S Brian Wilson, Amy Anderson, Amy R Howell, W Jaung, M Khalili
Research Type: Journal Article

An Unanticipated Ring-Opening of 2-Methyleneoxetanes: A Fundamentally New Approach to the Preparation of Homopropargylic Alcohols.
1998
L M Dollinger, Amy R Howell
Research Type: Journal Article

Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
2016
R T Lim, D G Pellicci, G S Besra, F J Ross, Amy R Howell, T Praveena, J Rossjohn, Stewart Richardson, S Keshipeddy, A P Uldrich, S Gras, D I Godfrey, N A Gherardin, J Le Nours
Research Type: Journal Article

Capturing the Reactivity of Unusual Oxetanes
2019
Amy R Howell
Research Type: Poster/Presentation

Challenges of Harnessing Glycolipid Stimulation of iNKT Cells
2019
Amy R Howell
Research Type: Poster/Presentation

Cloning and Characterization of a Hybridoma Secreting a 4-(Methylnitros-amino)-1-(3-pyridyl)-1-butanone (NNK)-Specific Monoclonal Antibody and Recombinant F(ab)
2013
Tolga Barker, Michael A. Lynes, Amy R Howell, Stewart K. Richardson, D. I. Zapata, G. P. Marusov, J. Zincgraf, Lawrence K. Silbart, D. Rood, Heather Wanczyk
Research Type: Journal Article

Cloning and characterization of a hybridoma secreting a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-specific monoclonal antibody and recombinant F(ab)
2013
Stewart Richardson, Heather Wanczyk, Lawrence K Silbart, Amy R Howell, greg Marusov, Michael A Lynes, Deborah Rood, D Zapata, T Barker
Research Type: Journal Article

Combining cross-metathesis and activity-based protein profiling: new β-lactone motifs for targeting serine hydrolases.
2015
B F Cravatt, S S Kamat, C C Lasota, Amy R Howell, K Camara
Research Type: Journal Article

Contact sensitizers trigger human CD1-autoreactive T-cell responses.
2017
S Mahapatra, L Mori, S Martinozzi Teissier, R J Betts, G De Libero, Amy R Howell, A Perkovic, A Del Bufalo, K Camara
Research Type: Journal Article