Amy R. Howell
Professor/Chemistry

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Scholarly Contributions

84 Scholarly Contributions

70
Journal Articles
13
Poster/Presentations
1
Patent and Intellectual Property
Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents.
2010
N Veerapen, S A Porcelli, J S Im, Y T Chang, K O Yu, G S Besra, M M Venkataswamy, G Bricard, P A Illarionov, Q Li, Amy R Howell, R M Ndonye
Research Type: Journal Article

Vβ2 Natural Killer T Cell Antigen Receptor-mediated Recognition of CD1d-Glycolipid Antigen
2011
Thierry Mallevaey, Jamie Rossjohn, Gurdyal S. Besra, Amy R Howell, Jingjing Zhang, Mugdha Bhati, Steven A Porcelli, Romain Bedel, Melissa McKnight, Onisha Patel, Laurent Gapin, Stewart K Richardson, Daniel G Pellicci, Andrew G Brooks, Lucy C Sullivan, James McCluskey, Lars Kjer-Nielsen, Dale I Godfrey, Adam P Uldrich
Research Type: Journal Article

Unusual, strained heterocycles: 3-alkylidene-2-methyleneoxetanes from Morita-Baylis-Hillman-type adducts.
2003
J D Emch, A E Andrews, J Wang, A J Ndakala, Amy R Howell, I Martínez
Research Type: Journal Article

Unexpected cleavage of 2-azido-2-(hydroxymethyl)oxetanes: conformation determines reaction pathway?
2010
E Farber, J Herget, Amy R Howell, J A Gascón
Research Type: Journal Article

Unexpected Reactivities of Unusual Oxetanes
2015
Amy R Howell
Research Type: Poster/Presentation

Towards a Formal Synthesis of Laureatin: Unexpected Rearrangements Involving Cyclic Ether Nucleophiles
2012
Martha D. Mortin, Bernard F. Castillo, Amy R Howell, Santosh K Keshipeddy, Isamir Martinez
Research Type: Journal Article

The molecular bases of δ/αβ T cell-mediated antigen recognition.
2014
Amy R Howell, S Gras, M H Heemskerk, R T Lim, J Le Nours, L Moretta, G Besra, J McCluskey, E Chabrol, D I Godfrey, D G Pellicci, R de Boer, F Ross, K McPherson, S B Eckle, A P Uldrich, J Rossjohn
Research Type: Journal Article

The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition.
2004
S D Maltsev, L Bénazet-Sidobre, R M Ndonye, T Sakai, Stewart Richardson, S Sidobre, G S Besra, M Kronenberg, K J Hammond, Amy R Howell, S A Porcelli
Research Type: Journal Article

The First General Synthesis of 1,5-Dioxaspiro[3.2]hexanes.
1998
Amy R Howell, A J Ndakala
Research Type: Journal Article

The Alpha and Omega of Galactosylceramides in T Cell Immune Function.
2015
A M Birkholz, Amy R Howell, M Kronenberg
Research Type: Journal Article

T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells.
2006
Q Zhang, L Gapin, J L Matsuda, Stewart Richardson, Amy R Howell, R Ndonye
Research Type: Journal Article

T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire.
2009
V Cerundolo, O Patel, J L Matsuda, Amy R Howell, D G Pellicci, J P Scott-Browne, L Kjer-Nielsen, M H Young, T Mallevaey, J McCluskey, M Thakur, Stewart Richardson, L Gapin, J Rossjohn, D I Godfrey, P Marrack
Research Type: Journal Article

Synthesis of epi-oxetin via a serine-derived 2-methyleneoxetane.
2008
Amy R Howell, M L Blauvelt
Research Type: Journal Article

Synthesis of a 2"-deoxy-β-GalCer.
2014
M Kronenberg, M S Thakur, Amy R Howell, A Khurana
Research Type: Journal Article

Synthesis of D-erythro-dihydrosphingosine and D-xylo-phytosphingosine from a serine-derived 1,5-dioxaspiro[3.2]hexane template.
2002
M Hashemzadeh, A J Ndakala, Amy R Howell, R C So
Research Type: Journal Article

Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH.
2005
D P Izmirian, S A Porcelli, K O Yu, M F Dunn, Stewart Richardson, Amy R Howell, A Khurana, M Kronenberg, R M Ndonye
Research Type: Journal Article

Synthesis and evaluation of an acyl-chain unsaturated analog of the Th2 biasing, immunostimulatory glycolipid, OCH.
2009
G Bricard, R Raju, Amy R Howell, G Velmourougane, G S Besra, J S Im, S A Porcelli
Research Type: Journal Article

Synthesis and evaluation of 3''- and 4''-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000.
2009
M Kronenberg, B F Castillo, Stewart Richardson, R Raju, R Severins, Amy R Howell, M Thakur
Research Type: Journal Article

Synthesis and Biological Activity of Glycolipid Activators of Type I NKT Cells
2019
Amy R Howell
Research Type: Poster/Presentation

Structural Modifications of αGalCer in Both Lipid and Carbohydrate Moiety Influence Activation of Murine and Human iNKT Cells
2015
Amy R Howell
Research Type: Journal Article