Amy R. Howell
Professor/Chemistry

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Novel Glycolipids that Elicit IFN-γ responses from Natural Killer T Cells
2011
J Wang, Amy R Howell, Aaron J Tyznik, Archana Khurana, Dirk M Zajonc, Alysia Birkholz, Yalli Li, Steven A Porcelli, Sampada C Chitale, Elisa Farber, Regina C So, Pooja Arora, Enrico Girardi, Mitchell Kronenberg
Research Type: Journal Article

Nickel or Cobalt Catalyzed Cross Coupling of Aryl Sulfonic Acid Salts with Grignard Reagents
2015
Amy R Howell
Research Type: Journal Article

New photoactivators for multiphoton excited three-dimensional submicron cross-linking of proteins: bovine serum albumin and type 1 collagen.
2002
J Wang, Amy R Howell, S L Goodman, P J Campagnola, I Banerjee, R Taboada, J D Pitts
Research Type: Journal Article

Natural killer T-cell autoreactivity leads to a specialized activation state.
2008
J E Gumperz, X Chen, G F Painter, A Huttenlocher, X Wang, L Rodenkirch, R M Ndonye, G S Besra, N Veerapen, Amy R Howell, D Gibson, S Wernimont, W Simonson
Research Type: Journal Article

Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells.
2008
K Kawahara, P H Seeberger, B Pei, Stewart Richardson, D Wu, M Imamura, C H Wong, Amy R Howell, A Khurana, M Fujio, S Bufali, M Kronenberg, Y Kinjo, R Raju
Research Type: Journal Article

Natural Product-inspired Glycolipids Providing Enhanced or Selective Activation of iNKT Cells
2012
Amy R Howell
Research Type: Poster/Presentation

Multiphoton excited fabrication of collagen matrixes cross-linked by a modified benzophenone dimer: bioactivity and enzymatic degradation.
2005
G D Pins, L P Cunningham, K A Bush, P J Campagnola, Amy R Howell, R Taboada, J Wang, S Basu
Research Type: Journal Article

Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae
2018
Mitchell Kronenberg, James Gray, William B. Kiosses, Bjoern Peters, Kaori Hitomi, Stewart Richardson, Amy R Howell, Natacha Veerapen, Catherine M. Crosby, Ashu Chawla, Sonia Sharma, Archana Khurana, Meng Zhao, Steven A. Porcelli, Shilpi Chandra, Zheng Fu, Gurdyal Besra
Research Type: Journal Article

Mouse and human iNKT cell agonist β-mannosylceramide reveals a distinct mechanism of tumor immunity.
2011
D S Khursigara, J A Berzofsky, S A Porcelli, E Ambrosino, B F Castillo, 2nd, H Y Kim, L Izhak, M Khalili, R Raju, P Illarionov, M Terabe, Amy R Howell, G S Besra, J J O'Konek
Research Type: Journal Article

Modular Dihydrobenzoazaphosphole Ligands for Suzuki–Miyaura Cross-Coupling
2018
J D Sieber, H Lee, J S Song, C Senanyake, Z S Han, Y Zhang, X J Wang, H Haddad, J N Desrosiers, Y Xu, N K Yee, Kendricks S Lao, Amy R Howell
Research Type: Journal Article

Methods of making lactone compounds and using the same for the treatment of neuroinflammatory diseases
2017
Research Type: Patent and Intellectual Property

Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation.
2009
K O Yu, M M Venkataswamy, A Molano, G Bricard, J S Im, E S Jerud, G S Besra, P Cresswell, W Yuan, A Baena, Amy R Howell, M F Goldberg, S A Porcelli, P A Illarionov, R M Ndonye, I Baine, P Arora, Y T Chang
Research Type: Journal Article

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator.
2007
T P Dilorenzo, S A Porcelli, G S Besra, Amy R Howell, A Molano, T Takaki, P Santamaria, J S Im, P Illarionov, R Ndonye, I Baine, C Forestier, E S Jerud
Research Type: Journal Article

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay.
2015
D H Chen, T D Bird, K Camara, W H Parsons, B F Cravatt, Amy R Howell, S S Kamat, M M Dix
Research Type: Journal Article

Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex
2012
Onisha Patel, S. A. Porcelli, Fiona Ross, Jamie Rossjohn, Santosh K. Keshipeddy, Stewart K. Richardson, Amy R Howell, K. S. Wun, Dale I. Godfrey, G. S. Besra
Research Type: Journal Article

Heterogeneous Catalytic Oxidation of Amides to Imides by Manganese Oxides
2018
Harshul S. Khanna, Amy R Howell, Partha Nandi, Quddus A. Nizami, Steven L Suib, Sumathy Raman, Katherine T. Cavanaugh, Donald R. Caldwell, Sourav Biswas
Research Type: Journal Article

Glycolipids that elicit IFN-γ-biased responses from natural killer T cells.
2011
A Birkholz, Y Li, M Kronenberg, A J Tyznik, S A Porcelli, Amy R Howell, R So, A Khurana, S Chitale, P Arora, J Wang, D M Zajonc, E Farber, E Girardi
Research Type: Journal Article

Exploiting Unexpected Reactivities of Unusual Oxetanes
2015
Amy R Howell
Research Type: Poster/Presentation

Efforts Towards a Formal Synthesis of Laureatin: An Unexpected NBS-mediated Skeletal Rearrangement
2011
Santosh Keshipeddy, Isamir Martinez, Bernard F Castillo, Martha D Morton, Amy R Howell
Research Type: Poster/Presentation

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.
2018
J H Lo, P Arora, Amy R Howell, D I Godfrey, L J Carreño, W Yuan, N A Saavedra-Avila, S Sundararaj, Stewart Richardson, X Wen, T Yongqing, D Chennamadhavuni, M J Guberman-Pfeffer, H F Koay, J A Gascón, J Rossjohn, J Le Nours, S A Porcelli, S Keshipeddy
Research Type: Journal Article