Amy R. Howell
Professor/Chemistry

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Alpha-S-GalCer: synthesis and evaluation for iNKT cell stimulation.
2008
J Paulsen, M L Blauvelt, S Brian Wilson, Amy Anderson, Amy R Howell, W Jaung, M Khalili
Research Type: Journal Article

Natural killer T-cell autoreactivity leads to a specialized activation state.
2008
J E Gumperz, X Chen, G F Painter, A Huttenlocher, X Wang, L Rodenkirch, R M Ndonye, G S Besra, N Veerapen, Amy R Howell, D Gibson, S Wernimont, W Simonson
Research Type: Journal Article

SGalCer Synthesis and evaluation for iNKT cell stimulation
2008
Amy Anderson, Amy R Howell
Research Type: Journal Article

Synthesis of epi-oxetin via a serine-derived 2-methyleneoxetane.
2008
Amy R Howell, M L Blauvelt
Research Type: Journal Article

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR.
2008
Stewart Richardson, R Koh, T Beddoe, D I Godfrey, Amy R Howell, M Thakur, L Kjer-Nielsen, L Gapin, J P Scott-Browne, J Rossjohn, K S Wun, N A Borg, J McCluskey
Research Type: Journal Article

Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells.
2008
K Kawahara, P H Seeberger, B Pei, Stewart Richardson, D Wu, M Imamura, C H Wong, Amy R Howell, A Khurana, M Fujio, S Bufali, M Kronenberg, Y Kinjo, R Raju
Research Type: Journal Article

Cross metathesis of alpha-methylene lactones II: gamma- and delta-lactones.
2007
T Le, C D Taylor, L J Allen, R Raju, Amy R Howell
Research Type: Journal Article

Production and characterization of monoclonal antibodies against complexes of the NKT cell ligand alpha-galactosylceramide bound to mouse CD1d.
2007
G S Besra, Amy R Howell, J S Im, P A Illarionov, K O Yu, R M Ndonye, S A Porcelli
Research Type: Journal Article

Rapid identification of immunostimulatory alpha-galactosylceramides using synthetic combinatorial libraries.
2007
P A Illarionov, Q Li, Amy R Howell, K O Yu, K Diaz, R M Ndonye, S A Porcelli, G S Besra, E S Jerud, Y T Chang, G Bricard
Research Type: Journal Article

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator.
2007
T P Dilorenzo, S A Porcelli, G S Besra, Amy R Howell, A Molano, T Takaki, P Santamaria, J S Im, P Illarionov, R Ndonye, I Baine, C Forestier, E S Jerud
Research Type: Journal Article

Cross metathesis with strained exocyclic enones: synthesis of 3-alkylideneoxetan-2-ones from 3-methyleneoxetan-2-ones.
2006
Amy R Howell, R Raju
Research Type: Journal Article

T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells.
2006
Q Zhang, L Gapin, J L Matsuda, Stewart Richardson, Amy R Howell, R Ndonye
Research Type: Journal Article

Multiphoton excited fabrication of collagen matrixes cross-linked by a modified benzophenone dimer: bioactivity and enzymatic degradation.
2005
G D Pins, L P Cunningham, K A Bush, P J Campagnola, Amy R Howell, R Taboada, J Wang, S Basu
Research Type: Journal Article

Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH.
2005
D P Izmirian, S A Porcelli, K O Yu, M F Dunn, Stewart Richardson, Amy R Howell, A Khurana, M Kronenberg, R M Ndonye
Research Type: Journal Article

The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition.
2004
S D Maltsev, L Bénazet-Sidobre, R M Ndonye, T Sakai, Stewart Richardson, S Sidobre, G S Besra, M Kronenberg, K J Hammond, Amy R Howell, S A Porcelli
Research Type: Journal Article

Straightforward synthesis of sphinganines via a serine-derived Weinreb amide.
2004
R L Guerrera, Stewart Richardson, R C So, Amy R Howell, R Ndonye, D P Izmirian
Research Type: Journal Article

Directed ring-opening of 1,5-dioxaspiro[3.2]hexanes: selective formation of 2,2-disubstituted oxetanes.
2003
G G Ordonio, A J Ndakala, R Taboada, Amy R Howell, P R Rablen
Research Type: Journal Article

Unusual, strained heterocycles: 3-alkylidene-2-methyleneoxetanes from Morita-Baylis-Hillman-type adducts.
2003
J D Emch, A E Andrews, J Wang, A J Ndakala, Amy R Howell, I Martínez
Research Type: Journal Article

Synthesis of D-erythro-dihydrosphingosine and D-xylo-phytosphingosine from a serine-derived 1,5-dioxaspiro[3.2]hexane template.
2002
M Hashemzadeh, A J Ndakala, Amy R Howell, R C So
Research Type: Journal Article

New photoactivators for multiphoton excited three-dimensional submicron cross-linking of proteins: bovine serum albumin and type 1 collagen.
2002
J Wang, Amy R Howell, S L Goodman, P J Campagnola, I Banerjee, R Taboada, J D Pitts
Research Type: Journal Article