Amy R. Howell
Professor/Chemistry

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Scholarly Contributions

84 Scholarly Contributions

70
Journal Articles
13
Poster/Presentations
1
Patent and Intellectual Property
Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay.
2015
D H Chen, T D Bird, K Camara, W H Parsons, B F Cravatt, Amy R Howell, S S Kamat, M M Dix
Research Type: Journal Article

Pt-catalyzed rearrangement of oxaspirohexanes to 3-methylenetetrahydrofurans: scope and mechanism.
2015
S M Chitale, R Taboada, Amy R Howell, M S Thakur, C A Malapit
Research Type: Journal Article

The molecular bases of δ/αβ T cell-mediated antigen recognition.
2014
Amy R Howell, S Gras, M H Heemskerk, R T Lim, J Le Nours, L Moretta, G Besra, J McCluskey, E Chabrol, D I Godfrey, D G Pellicci, R de Boer, F Ross, K McPherson, S B Eckle, A P Uldrich, J Rossjohn
Research Type: Journal Article

OMS-2 for Aerobic, Catalytic, One-pot Alcohol Oxidation-Wittig Reactions: Efficient Access to α,β-Unsaturated Esters
2014
Jagadeswara R Kona, Cecil K King'ondu, Steven L Suib, Amy R Howell
Research Type: Journal Article

Synthesis of a 2"-deoxy-β-GalCer.
2014
M Kronenberg, M S Thakur, Amy R Howell, A Khurana
Research Type: Journal Article

Cloning and Characterization of a Hybridoma Secreting a 4-(Methylnitros-amino)-1-(3-pyridyl)-1-butanone (NNK)-Specific Monoclonal Antibody and Recombinant F(ab)
2013
Tolga Barker, Michael A. Lynes, Amy R Howell, Stewart K. Richardson, D. I. Zapata, G. P. Marusov, J. Zincgraf, Lawrence K. Silbart, D. Rood, Heather Wanczyk
Research Type: Journal Article

Silicon acceleration of a tandem alkene isomerization/electrocyclic ring-opening of 2-methyleneoxetanes to α,β-unsaturated methylketones.
2013
Amy R Howell, E Farber, S Keshipeddy, K S Lao, A Rudnitskaya, Jose Gascon
Research Type: Journal Article

Cloning and characterization of a hybridoma secreting a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-specific monoclonal antibody and recombinant F(ab)
2013
Stewart Richardson, Heather Wanczyk, Lawrence K Silbart, Amy R Howell, greg Marusov, Michael A Lynes, Deborah Rood, D Zapata, T Barker
Research Type: Journal Article

Towards a Formal Synthesis of Laureatin: Unexpected Rearrangements Involving Cyclic Ether Nucleophiles
2012
Martha D. Mortin, Bernard F. Castillo, Amy R Howell, Santosh K Keshipeddy, Isamir Martinez
Research Type: Journal Article

Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex
2012
Onisha Patel, S. A. Porcelli, Fiona Ross, Jamie Rossjohn, Santosh K. Keshipeddy, Stewart K. Richardson, Amy R Howell, K. S. Wun, Dale I. Godfrey, G. S. Besra
Research Type: Journal Article

A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells.
2011
M S Thakur, D G Pellicci, S Keshipeddy, A G Brooks, A P Uldrich, O Patel, S A Porcelli, K S Wun, Amy R Howell, D I Godfrey, G S Besra, G Cameron, Stewart Richardson, P A Illarionov, J McCluskey, J Rossjohn, S S Pang, M H Young, L Gapin, L C Sullivan
Research Type: Journal Article

A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids.
2011
S K Chung, P Arora, J H Lee, G Bricard, M M Venkataswamy, A Baena, Q Li, S A Porcelli, K C Seo, N Veerapen, P A Illarionov, R Ndonye, J J Park, Amy R Howell, G S Besra, Y T Chang
Research Type: Journal Article

Mouse and human iNKT cell agonist β-mannosylceramide reveals a distinct mechanism of tumor immunity.
2011
D S Khursigara, J A Berzofsky, S A Porcelli, E Ambrosino, B F Castillo, 2nd, H Y Kim, L Izhak, M Khalili, R Raju, P Illarionov, M Terabe, Amy R Howell, G S Besra, J J O'Konek
Research Type: Journal Article

Vβ2 Natural Killer T Cell Antigen Receptor-mediated Recognition of CD1d-Glycolipid Antigen
2011
Thierry Mallevaey, Jamie Rossjohn, Gurdyal S. Besra, Amy R Howell, Jingjing Zhang, Mugdha Bhati, Steven A Porcelli, Romain Bedel, Melissa McKnight, Onisha Patel, Laurent Gapin, Stewart K Richardson, Daniel G Pellicci, Andrew G Brooks, Lucy C Sullivan, James McCluskey, Lars Kjer-Nielsen, Dale I Godfrey, Adam P Uldrich
Research Type: Journal Article

Glycolipids that elicit IFN-γ-biased responses from natural killer T cells.
2011
A Birkholz, Y Li, M Kronenberg, A J Tyznik, S A Porcelli, Amy R Howell, R So, A Khurana, S Chitale, P Arora, J Wang, D M Zajonc, E Farber, E Girardi
Research Type: Journal Article

Novel Glycolipids that Elicit IFN-γ responses from Natural Killer T Cells
2011
J Wang, Amy R Howell, Aaron J Tyznik, Archana Khurana, Dirk M Zajonc, Alysia Birkholz, Yalli Li, Steven A Porcelli, Sampada C Chitale, Elisa Farber, Regina C So, Pooja Arora, Enrico Girardi, Mitchell Kronenberg
Research Type: Journal Article

Access to Oxetane-containing psico-Nucleosides from 2-Methyleneoxetanes: A Role for Neighboring Group Participation?
2011
Paul R Rablen, Bryan T Whiting, John M Rowley, Yanke Liang, Martha M Morton, Nathan Hnatiuk, Geoffrey W Coates, Amy R Howell
Research Type: Journal Article

A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity.
2010
X Li, S B Wilson, P Stock, Amy R Howell, K O Yu, T Shiratsuchi, J Kerzerho, W Yang, O Akbari, M Kronenberg, V Lombardi, B A Sullivan, S A Porcelli, M Tsuji, A K Singh, N E Hnatiuk
Research Type: Journal Article

Unexpected cleavage of 2-azido-2-(hydroxymethyl)oxetanes: conformation determines reaction pathway?
2010
E Farber, J Herget, Amy R Howell, J A Gascón
Research Type: Journal Article

Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents.
2010
N Veerapen, S A Porcelli, J S Im, Y T Chang, K O Yu, G S Besra, M M Venkataswamy, G Bricard, P A Illarionov, Q Li, Amy R Howell, R M Ndonye
Research Type: Journal Article