Ashis K. Basu
Professor/Chemistry

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Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replication of (5'S)-8,5'-cyclopurine-2'-deoxynucleosides in vitro by DNA polymerase IV, exo-free Klenow fragment, and Dpo4.
2014
V Pednekar, S Weerasooriya, Ashis K Basu, V P Jasti
Research Type: Journal Article

Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase.
2014
C K Malik, V V Gadkari, Z Suo, E J Tokarsky, Ashis K Basu
Research Type: Journal Article

Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis.
2014
C K Malik, P Pande, Ashis K Basu, A Bose, V P Jasti
Research Type: Journal Article

Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences.
2014
V P Jasti, Ashis K Basu, S Weerasooriya
Research Type: Journal Article

Synthesis of [1,3, NH2-(15)N3] (5'S)-8,5'-cyclo-2'-deoxyguanosine.
2013
Ashis K Basu, R S Das, C K Malik
Research Type: Journal Article

Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase
2013
Ashis K Basu
Research Type: Journal Article

Structural Mechanism of Replication Stalling on a Bulky Amino-Polycyclic Aromatic Hydrocarbon DNA Adduct by a Y Family DNA Polymerase
2013
Ashis K Basu, Hong Ling, Kevin Kirouac
Research Type: Journal Article

Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases.
2012
S M Sherrer, Z Suo, C K Malik, L R Pack, Ashis K Basu, D J Taggart
Research Type: Journal Article

Structure of (5’S)-8,5’-cyclo-2’-deoxyguanosine mismatched with dA or dT
2012
Hui Huang, Ashis K Basu, Rajat S. Das, Michael P. Stone
Research Type: Journal Article

Stability of N-glycosidic bond of (5’S)-8,5’-cyclo-2’-deoxyguanosine
2012
Ashis K Basu
Research Type: Journal Article

Structures of (5'S)-8,5'-Cyclo-2'-deoxyguanosine Mismatched with dA or dT.
2012
Martha Stone, Ashis K Basu, R S Das, Hanchen Huang
Research Type: Journal Article

Repair efficiency of (5’S)-8,5’-cyclo-2’-deoxyguanosine and (5’S)-8,5’-cyclo-2’-deoxyadenosine depends on the complementary base
2012
Ashis K Basu
Research Type: Journal Article

Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-family DNA polymerases
2012
Eric R. Bolin, Zucai Suo, Laura E. Sanman, Georgia Efthimiopoulos, Shanen M. Sherrer, Chanchal K. Malik, Cynthia X. Xia, Ashis K Basu
Research Type: Journal Article

Structure of (5’S)-8,5’-cyclo-2’-deoxyguanosine in DNA
2011
Ashis K Basu, Rajat S. Das, Michael P. Stone, Hui Huang
Research Type: Journal Article

(5'S)-8,5'-cyclo-2'-deoxyguanosine is a strong block to replication, a potent pol V-dependent mutagenic lesion, and is inefficiently repaired in Escherichia coli.
2011
R S Das, Ashis K Basu, V P Jasti, S Weerasooriya, B A Hilton, Y Zou
Research Type: Journal Article

Genetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: DNA polymerases IV and V compete for error-prone bypass.
2011
P Raychaudhury, Ashis K Basu
Research Type: Journal Article

Tobacco-specific nitrosamine-derived O2-alkylthymidines are potent mutagenic lesions in SOS-induced Escherichia coli
2011
Ashis K Basu, Thomas E. Spratt, Vijay P. Jasti
Research Type: Journal Article

Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model.
2010
M Tomasz, Ashis K Basu, Yong Wang, M W Weng, Yu Zheng, V P Jasti, E Champeil, M S Tang
Research Type: Journal Article

Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion site.
2010
M Roginskaya, Y Zou, Kyle Brown, Ashis K Basu, A Altamirano, Michael P. Stone
Research Type: Journal Article

Replication Past the γ-Radiation-Induced Guanine-Thymine Cross-Link G[8,5-Me]T by Human and Yeast DNA Polymerase η.
2010
P Raychaudhury, Ashis K Basu
Research Type: Journal Article