Ashis K. Basu
Professor/Chemistry

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The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA.
2009
Ashis K Basu, Kyle Brown, Michael P. Stone
Research Type: Journal Article

Synthesis of oligonucleotides containing 2'-deoxyguanosine adducts of nitropyrenes.
2009
C McCarty, D Chakraborti, P Hilario, L C Colis, Ashis K Basu
Research Type: Journal Article

Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase.
2009
Ashis K Basu, Joyce Brown, L R Pack, Z Suo, S M Sherrer, J D Fowler, V P Jasti
Research Type: Journal Article

Inhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts.
2008
T J Burke, S Mukhopadhyay, J H Tolentino, Ashis K Basu, W G McGregor
Research Type: Journal Article

Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA.
2008
T Adams, Kyle Brown, V P Jasti, Ashis K Basu, Michael Stone
Research Type: Journal Article

Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase eta.
2008
L C Colis, Ashis K Basu, P Raychaudhury
Research Type: Journal Article

Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene in mammalian cells.
2007
Ashis K Basu, P Hilario, C D Utzat, D L Watt
Research Type: Journal Article

Genetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells.
2006
M A Kalam, Ashis K Basu, K Haraguchi, M M Greenberg, S Chandani, E L Loechler, M Moriya
Research Type: Journal Article

Repair of thymine glycol by hNth1 and hNeil1 is modulated by base pairing and cis-trans epimerization.
2006
G W Teebor, J E Ocampo, R P Cunningham, R J Boorstein, Ashis K Basu, M T Ocampo-Hafalla, A Altamirano, M K Chan
Research Type: Journal Article

Specific and efficient binding of xeroderma pigmentosum complementation group A to double-strand/single-strand DNA junctions with 3'- and/or 5'-ssDNA branches.
2006
P R Musich, Ashis K Basu, Y Zou, C M Harris, L C Colis, S M Shell, Z Yang, Yizao Liu, T M Harris, M Roginskaya
Research Type: Journal Article

Interactions of human replication protein A with single-stranded DNA adducts.
2005
Yizao Liu, Z Yang, Y Zou, N E Geacintov, C D Utzat, Yizao Liu, Ashis K Basu
Research Type: Journal Article

Mutagenesis of 8-oxoguanine adjacent to an abasic site in simian kidney cells: tandem mutations and enhancement of G-->T transversions.
2005
Ashis K Basu, M A Kalam
Research Type: Journal Article

Cooperative interaction of human XPA stabilizes and enhances specific binding of XPA to DNA damage.
2005
Yizao Liu, C Utzat, Ashis K Basu, Yizao Liu, Y Zou, G Wang, Z Yang
Research Type: Journal Article

DNA adduct of the mitomycin C metabolite 2,7-diaminomitosene is a nontoxic and nonmutagenic DNA lesion in vitro and in vivo.
2005
L A Ramos, C C Clement, M Tomasz, Apurba K Das, C D Utzat, Ashis K Basu
Research Type: Journal Article

Recognition and incision of gamma-radiation-induced cross-linked guanine-thymine tandem lesion G[8,5-Me]T by UvrABC nuclease.
2005
Y Zou, Ashis K Basu, L C Colis, Z Yang
Research Type: Journal Article

Synthesis of N2 2'-deoxyguanosine adducts formed by 1-nitropyrene.
2003
Ashis K Basu, R Schneider, L Colis, D Chakraborti
Research Type: Journal Article

Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease.
2003
Ashis K Basu, S M Shell, C Luo, Y Zou, N E Geacintov, C D Utzat, Z Yang
Research Type: Journal Article

Substrate specificity of human endonuclease III (hNTH1). Effect of human APE1 on hNTH1 activity.
2003
G W Teebor, M K Chan, Ashis K Basu, A Altamirano, R J Boorstein, D R Marenstein, R P Cunningham
Research Type: Journal Article

Comparative mutagenesis of the C8-guanine adducts of 1-nitropyrene and 1,6- and 1,8-dinitropyrene in a CpG repeat sequence. A slipped frameshift intermediate model for dinucleotide deletion.
2002
B E Hingerty, S Broyde, Ashis K Basu, P Hilario, S Yan
Research Type: Journal Article

Targeted deletion of mNth1 reveals a novel DNA repair enzyme activity.
2002
A Altamirano, M T Ocampo, Ashis K Basu, D R Marenstein, G W Teebor, R P Cunningham, R J Boorstein, W Chaung, M K Chan
Research Type: Journal Article