Raman Bahal
Associate Professor/Pharmaceutical Science

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γ Peptide Nucleic Acid-Based miR-122 Inhibition Rescues Vascular Endothelial Dysfunction in Mice Fed a High-Fat Diet.
2022
K Irani, Q Li, V Kumar, Yusun Kim, J S Jacobs, A Vikram, Raman Bahal, K Dhuri, R R Gaddam
Research Type: Journal Article

β-Catenin knockdown in liver tumor cells by a cell permeable gamma guanidine-based peptide nucleic acid.
2013
S P Monga, E Delgado, J M Lee, D H Ly, Raman Bahal, J Yang
Research Type: Journal Article

microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis.
2023
C Fernández-Hernando, S Ding, K S Rose, J C Schupp, M Chioccioli, G DeIuliis, G Ibarra, I Rosas, C S Dela Cruz, Xiaoyang Liu, C Cosmos, Jr, J E McDonough, T Bärnthaler, F Ahangari, J A Villalba Nunez, N R Aurelien, N L Price, S P Pradeep, Raman Bahal, A Prasse, Jung-Min Kim, T S Adams, S Malik, N Omote, C Ryu, N Kaminski, L Sharma
Research Type: Journal Article

Unlocking the potential of chemically modified peptide nucleic acids for RNA-based therapeutics.
2023
Raman Bahal, S P Pradeep, F J Slack, S Malik
Research Type: Journal Article

Tumor-Targeted, Cytoplasmic Delivery of Large, Polar Molecules Using a pH-Low Insertion Peptide.
2020
J C Deacon, Raman Bahal, F N Barrera, A A Svoronos, M C Pereira, D M Engelman, P M Glazer, D DiMaio, M Bosenberg
Research Type: Journal Article

Therapeutic Potential of Chemically Modified, Synthetic, Triplex Peptide Nucleic Acid-Based Oncomir Inhibitors for Cancer Therapy.
2021
R R Gaddam, K Dhuri, Raman Bahal, A Vikram, F J Slack
Research Type: Journal Article

Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities.
2017
Raman Bahal, A Ricciardi, W M Saltzman, P M Glazer, E Quijano
Research Type: Journal Article

The growth of siRNA-based therapeutics: Updated clinical studies
2021
May Zhang, xiaobo zhong, Raman Bahal, Theodore Rasmussen, Jose E Manautou
Research Type: Journal Article

Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin
2024
Prajith Stephen, Jordyn Belcourt, Alexis Frankel, Alicia Zongxun Wang, Sherouk M. Tawfik, Milan Shah, Theodore Rasmussen, Xiao Bo Zhong, Jing Jin, Anagha Gogate, Jose E Manautou, Aarush Kolli, Raman Bahal, Matthew Chalon, Holly Kolmel
Research Type: Other Scholarly Work

Targeting genomic DNA for cancer therapy, Invention disclosure submitted
2023
Research Type: Patent and Intellectual Property

Targeted Suppression of miRNA-33 Using pHLIP Improves Atherosclerosis Regression.
2022
A Moshnikova, N L Price, O A Andreev, N Rotllan, C Fernández-Hernando, Y K Reshetnyak, Y Suárez, M M Sadeghi, Raman Bahal, Xinxuan Zhang, W Zhong, E Araldi, S Malik, A Canfrán-Duque, Jianjun Sun, J Toczek
Research Type: Journal Article

Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility.
2011
I Sacui, D H Ly, B A Armitage, S Rapireddy, B Sahu, K J Zanotti, Raman Bahal
Research Type: Journal Article

Suppressing miR-21 activity in tumor-associated macrophages promotes an antitumor immune response.
2019
Y K Reshetnyak, D L Rimm, R García-Milian, Y Suárez, Yang Liu, A Kaplan, S Mehta, M Sahraei, P Fiorina, C Fernández-Hernando, B Chaube, Raman Bahal, Jianjun Sun, S Oyaghire, W Ding, N L Price, P M Glazer
Research Type: Journal Article

Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions.
2011
S Rapireddy, D H Ly, Raman Bahal
Research Type: Journal Article

Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs.
2009
S Rapireddy, Raman Bahal, D H Ly, B Sahu, G He
Research Type: Journal Article

Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition.
2014
D H Ly, W M Saltzman, N A McNeer, Raman Bahal, F Lopez-Giraldez, P M Glazer, R J Fields, E Quijano, Y Liu, D C Bhunia
Research Type: Journal Article

Simultaneous targeting of multiple oncomiRs with phosphorothioate or PNA-based anti-miRs in lymphoma cell lines
2022
Raman Bahal, Karishma Dhuri, Xiaobo Zhong, Sai Pallavi Pradeep, Frank J Slack, Jason Shi, Anisha Gupta, Eleni Anastasiadou
Research Type: Journal Article

Serine-γPNA, Invader probes, and chimeras thereof: three probe chemistries that enable sequence-unrestricted recognition of double-stranded DNA.
2022
Raman Bahal, R G Emehiser, C Shepard, S Karmakar, K Dhuri, P J Hrdlicka
Research Type: Journal Article

Sequence-unrestricted, Watson-Crick recognition of double helical B-DNA by (R)-miniPEG-γPNAs.
2012
B Sahu, D H Ly, C M Lee, Raman Bahal, S Rapireddy
Research Type: Journal Article

Role of Lipid-Based and Polymer-Based Non-Viral Vectors in Nucleic Acid Delivery for Next-Generation Gene Therapy.
2020
K Dhuri, A Gupta, A Waghmode, A Wahane, A Kapphahn, Raman Bahal
Research Type: Journal Article