Robin H. Bogner
Professor/Pharmaceutical Science

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Mechanisms by which crystalline mannitol improves the reconstitution time of high concentration lyophilized protein formulations
2018
Shreya S. Kulkarni, Raj Suryanarayanan, Joseph V. Rinella, Robin H Bogner
Research Type: Journal Article

Biorelevant Media Slows the Solution-Mediated Phase Transformation of Amorphous Spironolactone
2018
Robin H Bogner, Roy J. Haskell, Mary S. Kleppe
Research Type: Journal Article

Insights into Slow Reconstitution of Lyophilized Protein Formulations and Practical Methods to Increase Reconstitution Rates
2018
Robin H Bogner
Research Type: Poster/Presentation

Exploration of Protein Tertiary Conformational Changes in Lyophilized Protein Samples using Raman Spectroscopy and Principal Components Analysis
2018
Lauren Fontana, Michael J Pikal, Robin H Bogner
Research Type: Poster/Presentation

Effect of process parameters on stability of lactate dehydrogenase during bulk freeze-thaw
2018
Robin H Bogner, Li Sun, Tai-hsi Fan, Bruna Minatovicz, Ji-Qin Li, Bodhisattwa Chaudhuri
Research Type: Poster/Presentation

Factors governing the reconstitution time of highly concentrated lyophilized proteins in amorphous formulations
2018
Shreya Kulkarni, Robin H Bogner, Sajal M Patel
Research Type: Poster/Presentation

Potential factors governing reconstituion time of high concentration lyophilized protein formulations
2018
Robin H Bogner, Shreya Kulkarni, Sajal Patel
Research Type: Poster/Presentation

Factors Governing the Reconstitution Time of High-Concentration Lyophilized Protein Formulations
2018
Shreya Kulkarni, Robin H Bogner
Research Type: Poster/Presentation

Freeze-drying of highly concentrated proteins: Effect of formulation and processing on phase composition, porous structure and reconstitution time
2018
Joseph V Rinella, Raj Suryanarayanan, Robin H Bogner, Shreya Kulkarni
Research Type: Poster/Presentation

Oral Ingestion and Intraventricular Injection of Curcumin Attenuates the Effort-Related Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Motivational Symptoms of Depression
2017
Samantha Collins, Merce Correa, Robin H Bogner, Anisha Mistry, Dea Gorka, John D Salamone, Samantha E. Yohn, Arushi Manchanda, Emily Qian
Research Type: Journal Article

Dissolution of a colloidal particle in an oscillatory flow
2017
Robin H Bogner, Tai-hsi Fan, Dezhuang Ye, Jiqin Li
Research Type: Journal Article

Spatial Variation of Pressure in the Lyophilization Product Chamber Part 2: Experimental Measurements and Implications for Scale-up and Batch Uniformity
2017
Robin H Bogner
Research Type: Journal Article

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Can Raman Spectroscopy Detect Protein Tertiary Conformational Changes in Lyophilized Samples?
2017
Lauren Fontana, Michael J Pikal, Robin H Bogner
Research Type: Poster/Presentation

Why does crystallization of mannitol lower the reconstitution times of freeze-dried highly concentrated protein formulations?
2017
Shreya S Kulkarni, Robin H Bogner
Research Type: Poster/Presentation

How precise is the amorphous solubility enhancement ratio?
2017
Mary S Kleppe, Arushi A Manchanda, Robin H Bogner
Research Type: Poster/Presentation

Does crystalline mannitol always lower the reconstitution time of freeze-dried highly concentrated protein formulations?
2017
Joseph Rinella, Robin H Bogner, Shreya Kulkarni, Raj Suryanarayanan
Research Type: Poster/Presentation

Impact of controlled ice nucleation on the quality of freeze-dried protein formulations
2017
Robin H Bogner, Rui Fang, Michael J Pikal
Research Type: Poster/Presentation

Effect of Processing Conditions on Reconstitution Time of High Concentration Lyophilized Protein FOrmulations Containing a Crystallizable Excipient
2017
Robin H Bogner, Joseph Rinella, Raj Suryanarayanan, Shreya Kulkarni
Research Type: Poster/Presentation

Effect of formulation and processing on physical attributes of lyophilized cakes of highly concentrated proteins
2017
Shreya S Kulkarni, Robin H Bogner
Research Type: Poster/Presentation

The Effects of Temperature on Solubility and Solution-Mediated Crystallization of Amorphous Spironolactone
2017
Mary S Kleppe, Robin H Bogner
Research Type: Poster/Presentation