Xiaobo Zhong
Professor/Pharmaceutical Science

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siRNA drug Leqvio (inclisiran) to lower cholesterol
2022
Julia M Migliorati, xiaobo zhong, Jing Jin
Research Type: Journal Article

Variability in expression of the human MDR1 drug efflux transporter and genetic variation of the ABCB1 gene: implications for drug-resistant epilepsy
2018
Anna Heinrich, xiaobo zhong, Theodore Rasmussen
Research Type: Other Scholarly Work

Transcriptome Features of an HepaRG Cell Line Over-Expressing Human Flavin-Containing Monooxygenase-3 (FMO3)
2016
Jose E Manautou, xiaobo zhong, Swetha Rudraiah, Winfried H Krueger, Stephanie Peikos, Theodore Rasmussen
Research Type: Poster/Presentation

The roles of long noncoding RNAs HNF1α-AS1 and HNF4α-AS1 in drug metabolism and human diseases
2020
Suzhen Jiang, Xiao-bo Zhong, Yifan Bao, Liming Chen
Research Type: Journal Article

The role of long non-coding RNAs HNF1a-AS1 and HNF4a-AS1 in the regulation of drug metabolizing cytochrome P450 enzymes and nuclear receptors in liver cells
2018
Liming Chen, Yifan Bao, xiaobo zhong, Stephanie C Piekos
Research Type: Poster/Presentation

The role of hepatocyte nuclear factor 1 alpha (HNF1a) and long non-coding RNA HNF1a antisense 1 (HNF1a-AS1) in the regulation of cytochrome P450s and nuclear receptors in liver cells
2017
xiaobo zhong, Liming Chen, Stephanie C Piekos, Yifan Bao
Research Type: Poster/Presentation

The role of H19, a long non-coding RNA, in mouse liver during postnatal maturation
2016
Stephanie Piekos, xiaobo zhong, Chad Pope
Research Type: Poster/Presentation

The role of FXR in the regulation of phase-I drug metabolizing gene expression during mouse liver maturation
Hong Lu, Lai Peng, Yue Julia Cui, Byunggil Yoo, Curtis D Klaassen, xiaobo zhong, Yun-chen Tien
Research Type: Conference Proceedings

The role of FXR in the regulation of Phase-I drug metabolizing gene expression during mouse liver maturation
2014
Julia Cui, Curtis Klaassen, Hong Lu, Yun-chun Tien, Byunggil Yoo, Lai Peng, xiaobo zhong
Research Type: Poster/Presentation

The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4
2024
Qi Wang, Pei Wang, Wanglai Hu, Yiting Wang, Lirong Zhang, Rick F. Thorne, xiaobo zhong, Shitong Chen, Xiaofei Wang, Shengna Han
Research Type: Journal Article

The growth of siRNA-based therapeutics: Updated clinical studies
2021
May Zhang, xiaobo zhong, Raman Bahal, Theodore Rasmussen, Jose E Manautou
Research Type: Journal Article

The Temporal Expression and Regulation of an Imprinted Gene Network during Postnatal Liver Development in Mice
Lai Peng, xiaobo zhong, Stephanie Piekos
Research Type: Conference Proceedings

The Role of Long Non-coding RNAs in Postnatal Liver Maturation
2016
xiaobo zhong
Research Type: Poster/Presentation

The Role of H19, a Long Non-coding RNA, in Mouse Liver Postnatal Maturation
2017
Stephanie C Piekos, Liming Chen, Chad Pope, Shashank Mishra, xiaobo zhong
Research Type: Journal Article

The HNF1a-Regulated LncRNA HNF1a-AS1 Is Involved in theRegulation of Cytochrome P450 Expression in Human LiverTissues and Huh7 Cells
2019
Yali Nie, Liang Yan, Lirong Zhang, Liming Chen, Jingyang Liu, Guangming Liu, Shitong Chen, Yiting Wang, Weihong Yang, xiaobo zhong, Pei Wang, Shengna Han
Research Type: Journal Article

The Long Non-coding RNA HNF4A-AS1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications
2021
Yiting Wang, Kun Yang, Xiaofei Wang, Pei Wang, Lirong Zhang, Shitong Chen, Liang Yan, xiaobo zhong, Shengna Han
Research Type: Journal Article

Targeting the liver with nucleic acid therapeutics for the treatment of systemic diseases of liver origin.
2024
Anagha Gogate, Prajith Stephen, Sherouk M Tawfik, Milan Shah, Jose E Manautou, Holly Kolmel, Jordyn Belcourt, Jing Jin, Theodore Rasmussen, Alexis Frankel, Raman Bahal, Alicia Zongxun Wang, Matthew Chalon, xiaobo zhong, Aarush Kolli
Research Type: Journal Article

Targeting liver with nucleic acid therapeutics for the treatment of liver-originated systemic diseases
2022
xiaobo zhong
Research Type: Poster/Presentation

Targeting H19, an imprinted long non-coding RNA, in hepatic functions and liver diseases
2017
xiaobo zhong, Shashank Mishra, Joshua Russell, Qingqing Zhou, Chad Pope
Research Type: Journal Article

Strategy for the development of precision medicine based on drug metabolism
2018
xiaobo zhong
Research Type: Poster/Presentation