Adam Zweifach
Professor/Molecular and Cell Biology
Storrs Mansfield
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Scholarly Contributions
25 Scholarly Contributions
A High Throughput Phenotypic Screen of Cytotoxic T Lymphocyte Lytic Granule Exocytosis Reveals Candidate Immunosuppressants
2015
Research Type: Journal Article
A Multiplexed Assay That Monitors Effects of Multiple Compound Treatment Times Reveals Candidate Immune-Enhancing Compounds.
2018
Research Type: Journal Article
A Novel Multiple-Read Screen for Metabolically Active Compounds Based on a Genetically Encoded FRET Sensor for ATP.
2018
Research Type: Journal Article
A novel ensemble approach to providing small molecule support for validation of cellular targets confirms that glycolysis inhibition is a viable antiproliferative strategy in leukemic cells
2017
Research Type: Poster/Presentation
A novel ensemble approach to providing small molecule support for validation of cellular targets confirms that glycolysis is a viable antiproliferative strategy in leukemic cells.
2017
Research Type: Poster/Presentation
Calcineurin activation is only one calcium-dependent step in cytotoxic T lymphocyte granule exocytosis.
2007
Research Type: Journal Article
Calcineurin-dependent lytic granule exocytosis in NK-92 natural killer cells.
2009
Research Type: Journal Article
Calcium influx and signaling in cytotoxic T-lymphocyte lytic granule exocytosis.
2009
Research Type: Journal Article
Development of an Enhanced Phenotypic Screen of Cytotoxic T-Lymphocyte Lytic Granule Exocytosis Suitable for Use with Synthetic Compound and Natural Product Collections.
2016
Research Type: Journal Article
ERK activation is only one role of PKC in TCR-independent cytotoxic T cell granule exocytosis.
2008
Research Type: Journal Article
Flow Cytometry Enables A High-Throughput Homogeneous Fluorescent Antibody-Binding Assay for Cytotoxic T Cell Lytic Granule Exocytosis.
Research Type: Journal Article
Flow Cytometry Enables Multiplexed Measurements of Genetically Encoded Intramolecular FRET Sensors Suitable for Screening.
2016
Research Type: Journal Article
Flow cytometry enables multiplexed measurements of genetically-encoded sensors based on intramolecular Förster resonance energy transfer.
2016
Research Type: Poster/Presentation
Journeying with Cytotoxic T lymphocytes from Signaling to Phenotypic Screening: and some lessons learned along the way
2019
Research Type: Poster/Presentation
Journeying with Cytotoxic T lymphocytes from Signaling to Phenotypic Screening: and some lessons learned along the way
2019
Research Type: Poster/Presentation
Metallothionein regulates intracellular zinc signaling during CD4(+) T cell activation.
2016
Research Type: Journal Article
No specific subcellular localization of protein kinase C is required for cytotoxic T cell granule exocytosis.
2009
Research Type: Journal Article
Novel high throughput assays for cytotoxic T lymphocyte function based on flow cytometry.
2014
Research Type: Poster/Presentation