Dennis Wright
Professor/Pharmaceutical Science

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Scholarly Contributions

132 Scholarly Contributions

68
Journal Articles
46
Conference Proceedings
14
Poster/Presentations
3
Patent and Intellectual Propertys
1
Book
HMGB2 is a potential diagnostic marker and therapeutic target for liver fibrosis and cirrhosis.
2023
Yen Chih Huang, N Huda, Antonio P Costa, Dennis Wright, S K Keshipeddy, J Ma, Diane J Burgess, S Rudraiah, Y Zhang, L Wang, Zhihong Yang, S Liangpunsakul
Research Type: Journal Article

Two-Metal Ion-Dependent Enzymes as Potential Antiviral Targets in Human Herpesviruses.
2022
S Weerasooriya, Lee Wright, A Hazeen, K A DiScipio, S K Weller, Dennis Wright, R Szczepaniak
Research Type: Journal Article

Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus.
2022
V G Fowler, S M Reeve, M S Frenkel, A A Ojewole, Dennis Wright, S Keshipeddy, B R Donald, G T Holt, P Gainza, Shuwen Wang
Research Type: Journal Article

Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
2022
Dennis Wright, A Estrada, J Krucinska, H Erlandsen, K Viswanathan, D Si, Michael Lombardo
Research Type: Journal Article

Heterocyclic Enzyme Inhibitors Targeting Drug Resistant Pathogens
2022
Dennis Wright
Research Type: Poster/Presentation

Novel guanidine compounds inhibit platelet-derived growth factor receptor alpha transcription and oligodendrocyte precursor cell proliferation.
2021
A Sherafat, W M Wood, S Sakya, Jingfeng Song, J Medved, Akiko Nishiyama, Dennis Wright, M D van Heyst
Research Type: Journal Article

Structural and Biochemical Studies on Trimethoprim Resistant DHFR from Pathogenic Bacteria
2020
Dennis Wright
Research Type: Poster/Presentation

Targeting Essential Metabolic Pathways for Antibacterials
2020
Dennis Wright
Research Type: Poster/Presentation

Structural and Biochemical Studies of Trimethoprim Resistant DHFR from Pathogenic Bacteria
2020
Dennis Wright
Research Type: Poster/Presentation

Antimicrobials Targeting Central Metabolism
2020
Dennis Wright
Research Type: Poster/Presentation

Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.
2019
A Hazeen, H Erlandsen, Michael Lombardo, J G Pattis, J Krucinska, Eric May, S S Duay, Dennis Wright, Victoria L Robinson
Research Type: Journal Article

Post-Glycosylation Diversification (PGD): An Approach for Assembling Collections of Glycosylated Small Molecules
2019
Adam Zweifach, Dennis Wright, Chris Lorenc, Santosh Keshipeddy, Victoria L. Robinson, Ala M. Shaqra, Liza Henowitz, Zachary Cannone, Mark W Peczuh
Research Type: Journal Article

Structure guided in-vitro to in-vivo pharmacokinetic optimization of propargyl-linked antifolates.
2019
N Priestley, P Barney, J Hoody, D Si, L Walker, S M Reeve, Dennis Wright, W Zhou, Michael Lombardo, R S Obach, N G-Dayanandan, J Alverson, S Keshipeddy
Research Type: Journal Article

Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.
2019
B Hajian, J Krucinska, A Estrada, Dennis Wright, K Viswanathan, E Scocchera, K Miku≈°ová, M Cynamon, H Erlandsen, N G-Dayanandan, J Korduláková, C Shoen
Research Type: Journal Article

Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus.
2019
N D Gibson, J Krucinska, S S Agabiti, Y Yan, D Si, M S Frenkel, A Estrada, G T Holt, J B Alverson, S M Reeve, K Viswanathan, N D Priestley, A A Ojewole, B R Donald, Andrew Wiemer, Dennis Wright, S Wang
Research Type: Journal Article

Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
2019
Michael Lombardo, H Erlandsen, Victoria L Robinson, Dennis Wright, J Krucinska, E Falcone, A Estrada, A Hazeen, Amy Anderson
Research Type: Journal Article

Tropolone-induced effects on the unfolded protein response pathway and apoptosis in multiple myeloma cells are dependent on iron.
2019
S L Haney, G Talmon, Y S Chhonker, N G-Dayanandan, D J Murry, H R Safranek, Andrew Wiemer, Dennis Wright, M L Varney, S A Holstein
Research Type: Journal Article

ZWITTERIONIC PROPARGYL-LINKED ANTIFOLATES USEFUL FOR TREATING BACTERIAL INFECTIONS
2019
Dennis Wright
Research Type: Patent and Intellectual Property

Targeting Essential Metabolic Pathways
2019
Dennis Wright
Research Type: Poster/Presentation

Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound
2018
M. J. Bond, N. G-Dayanan, S. Keshipeddy, Dennis Wright, D. W. Rosenberg, M. Bleiler, L. E. Harrison, E. W. Scocchera, Charles A Giardina, M. Nakanishi
Research Type: Journal Article