Dennis Wright
Professor/Pharmaceutical Science

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Scholarly Contributions

132 Scholarly Contributions

68
Journal Articles
46
Conference Proceedings
14
Poster/Presentations
3
Patent and Intellectual Propertys
1
Book
Compounds for lysosomal modulation and methods of use
2009
Dennis Wright
Research Type: Patent and Intellectual Property

Crystal Structures of Wildtype and Mutant Methicillinresistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternate Conformation of NADPH That May Be Linked to Trimethoprim Resistance
Amy Anderson, Michael Lombardo, Dennis Wright
Research Type: Conference Proceedings

Crystal structures of Klebsiella pneumoniae dihydrofolate reductase bound to propargyl-linked antifolates reveal features for potency and selectivity.
2014
Michael Lombardo, Amy Anderson, N D Priestley, J Alverson, Dennis Wright, K M Lamb
Research Type: Journal Article

Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
2009
Dennis Wright, Michael Lombardo, Amy Anderson, D B Bolstad, J Liu, K M Frey
Research Type: Journal Article

Cyclopropene cycloadditions with annulated furans: Total synthesis of (+) frondosin A and (+) and (-) frondosin B
2014
Dennis Wright, Micahael VanHeyst
Research Type: Poster/Presentation

Cyclopropene cycloadditions with annulated furans: total synthesis of (+)- and (-)-frondosin B and (+)-frondosin a
2014
E Zachary Oblak, Michael D VanHeyst, Jin Li, Dennis Wright, Andrew Wiemer
Research Type: Journal Article

Deoxygenation/methylation of heteroaryl propargyl alcohols: Methods to generate unsubstituted, mono-, and di-methylated alkynes
2014
Dennis Wright, Narendran G-Dyanana, Eric Scocchera
Research Type: Poster/Presentation

Design and synthesis of novel antifolates as potent inhibitors of Bacillus anthracis
2012
Amy Anderson, Beierlin Jennifer, Dennis Wright, Viswanathan Kishore
Research Type: Poster/Presentation

Development of intestinal organoids as tissue surrogates: cell composition and the epigenetic control of differentiation.
2015
Wanli Xu, Jason D Gibson, Dennis Wright, L Cao, F Kolling, 4th, A Kuratnik, M D Van Heyst, E R Falcone, M Ammar, Charles A Giardina, C E Nelson
Research Type: Journal Article

Dihydrofolate reductase inhibitors Developments in antiparasitic chemotherapy
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks.
2017
E W Scocchera, S Keshipeddy, Amy Anderson, Dennis Wright, H F Jones, N G-Dayanandan
Research Type: Journal Article

Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.
2019
B Hajian, J Krucinska, A Estrada, Dennis Wright, K Viswanathan, E Scocchera, K Miku≈°ová, M Cynamon, H Erlandsen, N G-Dayanandan, J Korduláková, C Shoen
Research Type: Journal Article

Electrochemical annulation of fivemembered rings through dearomatization of furans and thiophenes
Dennis Wright
Research Type: Conference Proceedings

Electrooxidative coupling of furans and silyl enol ethers Application to the synthesis of annulated furans
Dennis Wright
Research Type: Conference Proceedings

Facile generation of aziridines from the reaction of diazoamides with tethered oximinoethers
Dennis Wright
Research Type: Conference Proceedings

Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.
2019
A Hazeen, H Erlandsen, Michael Lombardo, J G Pattis, J Krucinska, Eric May, S S Duay, Dennis Wright, Victoria L Robinson
Research Type: Journal Article

Furan Derived Building Blocks for Natural Products
2012
Dennis Wright
Research Type: Poster/Presentation

Furan as a versatile synthon
Dennis Wright
Research Type: Conference Proceedings

Furans thiophenes and related heterocycles in drug discovery
Dennis Wright
Research Type: Conference Proceedings

HMGB2 is a potential diagnostic marker and therapeutic target for liver fibrosis and cirrhosis.
2023
Yen Chih Huang, N Huda, Antonio P Costa, Dennis Wright, S K Keshipeddy, J Ma, Diane J Burgess, S Rudraiah, Y Zhang, L Wang, Zhihong Yang, S Liangpunsakul
Research Type: Journal Article