Dennis Wright
Professor/Pharmaceutical Science

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Halogenated oxabicyclo321octadiene building blocks Elaboration of the dibromoenone
Research Type: Conference Proceedings

Heterocycles in Drug Discovery
2012
Research Type: Poster/Presentation

Heterocyclic Enzyme Inhibitors Targeting Drug Resistant Pathogens
2022
Research Type: Poster/Presentation

High-mobility-group protein 2 regulated by microRNA-127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells
2017
R. Wu, Dennis Wright, Li Wang, Y. Zhao, Zhihong Yang, J. Wu, S. K. Keshipeddy
Research Type: Journal Article

Highly Substituted Oxabicyclic Derivatives from Furan: Synthesis of (±)-Platensimycin
2011
Dennis Wright, Edward Oblak
Research Type: Journal Article

Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis
2007
Amy Anderson, Dennis Wright
Research Type: Journal Article

In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans.
2009
A E Smith, D B Bolstad, Dennis Wright, N D Priestley, Amy Anderson, J L Paulsen, J Liu
Research Type: Journal Article

In vitro biological activity and structural analysis of 24diamino52arylpropargylpyrimidine inhibitors of Candida albicans
2009
Dennis Wright, Amy Anderson
Research Type: Journal Article

Inhibitors of DHFR as New Antimicrobials
2012
Research Type: Poster/Presentation

Inhibitors of Dihydrofolate Reductase with Antibacterial, Antiprotozoal, Antifungal and Anticancer Properties
2013
Research Type: Patent and Intellectual Property

Inhibitors of phosphoinositide-3-kinase: a structure-based approach to understanding potency and selectivity.
2009
Amy Anderson, Dennis Wright, T J Sundstrom
Research Type: Journal Article

Inhibitors of phosphoinositide3kinase A structurebased approach to understanding potency and selectivity
2009
Amy Anderson, Dennis Wright
Research Type: Journal Article

Intramolecular aziridination Decomposition of diazoamides with tethered imino bonds
Research Type: Conference Proceedings

MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.
2016
Amy Anderson, Jeffrey R Aeschlimann, Dennis Wright, S Keshipeddy, E W Scocchera, B Hajian, J Ferreira, N G-Dayanadan, J Krucinska, S M Reeve, Michael D Nailor
Research Type: Journal Article

MRSA isolates from the United States hospitals carry dfrG and drfK resistance genes and succumb to propargyl-linked antifolates
2016
S M Reeve, Jeffrey R Aeschlimann, Michael D Nailor, Amy Anderson, J Ferreira, J Krucinska, N G Dayanadan, B Hajjan, E W Scocchera, S Keshipeddy, Dennis Wright
Research Type: Journal Article

Mapping phorbol ester binding domains of protein kinase C PKC The design synthesis and biological activity of novel phorbol ester dimers
Research Type: Conference Proceedings

Measuring propargyl-linked drug populations inside bacterial cells, and their interaction with a dihydrofolate reductase target, by Raman microscopy.
2015
H Heidari-Torkabadi, P R Carey, Michael Lombardo, T Che, Dennis Wright, Amy Anderson
Research Type: Journal Article

Multivalent binding in the design of bioactive compounds
Research Type: Conference Proceedings

Natural feedstocks for diversity oriented synthesis: macrolide-like scaffolds from nonactate
2011
Nigel Priestley, P Whitney Swain, Dennis Wright, Stephen Bergmeier, Mark McMills, Yuliya Sumskaya
Research Type: Journal Article

Natural product derivatives with bactericidal activity against Grampositive pathogens including methicillinresistant Staphylococcus aureus and vancomycinresistant Enterococcus faecalis
2010
Research Type: Journal Article