Dennis Wright
Professor/Pharmaceutical Science

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Scholarly Contributions

132 Scholarly Contributions

68
Journal Articles
46
Conference Proceedings
14
Poster/Presentations
3
Patent and Intellectual Propertys
1
Book
SilverPromoted Reactions of Bicyclo321octadiene Derivatives
Dennis Wright
Research Type: Conference Proceedings

Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound
2018
M. J. Bond, N. G-Dayanan, S. Keshipeddy, Dennis Wright, D. W. Rosenberg, M. Bleiler, L. E. Harrison, E. W. Scocchera, Charles A Giardina, M. Nakanishi
Research Type: Journal Article

Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species.
2013
Amy Anderson, J L Paulsen, Dennis Wright, K Viswanathan
Research Type: Journal Article

Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligandinduced conformational changes shared among species
2013
Janet Paulsen, Amy Anderson, Kishore Viswanathan, Dennis Wright
Research Type: Journal Article

Structural and Biochemical Studies of Trimethoprim Resistant DHFR from Pathogenic Bacteria
2020
Dennis Wright
Research Type: Poster/Presentation

Structural and Biochemical Studies on Trimethoprim Resistant DHFR from Pathogenic Bacteria
2020
Dennis Wright
Research Type: Poster/Presentation

Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
2019
Michael Lombardo, H Erlandsen, Victoria L Robinson, Dennis Wright, J Krucinska, E Falcone, A Estrada, A Hazeen, Amy Anderson
Research Type: Journal Article

Structure guided in-vitro to in-vivo pharmacokinetic optimization of propargyl-linked antifolates.
2019
N Priestley, P Barney, J Hoody, D Si, L Walker, S M Reeve, Dennis Wright, W Zhou, Michael Lombardo, R S Obach, N G-Dayanandan, J Alverson, S Keshipeddy
Research Type: Journal Article

Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
2008
Amy Anderson, S Ananthan, N Schormann, O Senkovich, K Walker, Dennis Wright, S Velu, B Shinkre, A Rosowsky, D Chattopadhyay
Research Type: Journal Article

Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from cryptosporidium.
2008
Dennis Wright, K M Frey, E S Bolstad, D B Bolstad, Amy Anderson
Research Type: Journal Article

Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase.
2008
Amy Anderson, J Liu, N D Priestley, Dennis Wright, D B Bolstad, A E Smith
Research Type: Journal Article

Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
2022
Dennis Wright, A Estrada, J Krucinska, H Erlandsen, K Viswanathan, D Si, Michael Lombardo
Research Type: Journal Article

StructureGuided Development of Efficacious Antifungal Agents Targeting Candida glabrata Dihydrofolate Reductase
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

Structurebased approach to pharmacophore identification in silico screening and threedimensional quantitative structureactivity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function
2008
Dennis Wright, Amy Anderson
Research Type: Journal Article

Structurebased approach to the development of potent and selective inhibitors of dihydrofolate reductase from Cryptosporidium
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

Studies on inducers of nerve growth factor Synthesis of the cyathin core
Dennis Wright
Research Type: Conference Proceedings

Studies on the DielsAlder reaction of annulated furans Application to the synthesis of substituted phenanthrenes
Dennis Wright
Research Type: Conference Proceedings

Studies on the reactivity of CDDO a promising new chemopreventive and chemotherapeutic agent Implications for a molecular mechanism of action
Kenneth Couch, Amy Anderson, Dennis Wright
Research Type: Conference Proceedings

Studies on the sequential multicomponent couplingDielsAlder cycloaddition reaction
Dennis Wright
Research Type: Conference Proceedings

Synthesis of a functionalized oxabicyclo221heptenebased chemical library
2012
Dennis Wright
Research Type: Journal Article