Dennis Wright
Professor/Pharmaceutical Science

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Scholarly Contributions

132 Scholarly Contributions

68
Journal Articles
46
Conference Proceedings
14
Poster/Presentations
3
Patent and Intellectual Propertys
1
Book
Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
2022
Dennis Wright, A Estrada, J Krucinska, H Erlandsen, K Viswanathan, D Si, Michael Lombardo
Research Type: Journal Article

Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase.
2008
Amy Anderson, J Liu, N D Priestley, Dennis Wright, D B Bolstad, A E Smith
Research Type: Journal Article

Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from cryptosporidium.
2008
Dennis Wright, K M Frey, E S Bolstad, D B Bolstad, Amy Anderson
Research Type: Journal Article

Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
2008
Amy Anderson, S Ananthan, N Schormann, O Senkovich, K Walker, Dennis Wright, S Velu, B Shinkre, A Rosowsky, D Chattopadhyay
Research Type: Journal Article

Structure guided in-vitro to in-vivo pharmacokinetic optimization of propargyl-linked antifolates.
2019
N Priestley, P Barney, J Hoody, D Si, L Walker, S M Reeve, Dennis Wright, W Zhou, Michael Lombardo, R S Obach, N G-Dayanandan, J Alverson, S Keshipeddy
Research Type: Journal Article

Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
2019
Michael Lombardo, H Erlandsen, Victoria L Robinson, Dennis Wright, J Krucinska, E Falcone, A Estrada, A Hazeen, Amy Anderson
Research Type: Journal Article

Structural and Biochemical Studies on Trimethoprim Resistant DHFR from Pathogenic Bacteria
2020
Dennis Wright
Research Type: Poster/Presentation

Structural and Biochemical Studies of Trimethoprim Resistant DHFR from Pathogenic Bacteria
2020
Dennis Wright
Research Type: Poster/Presentation

Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligandinduced conformational changes shared among species
2013
Janet Paulsen, Amy Anderson, Kishore Viswanathan, Dennis Wright
Research Type: Journal Article

Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species.
2013
Amy Anderson, J L Paulsen, Dennis Wright, K Viswanathan
Research Type: Journal Article

Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound
2018
M. J. Bond, N. G-Dayanan, S. Keshipeddy, Dennis Wright, D. W. Rosenberg, M. Bleiler, L. E. Harrison, E. W. Scocchera, Charles A Giardina, M. Nakanishi
Research Type: Journal Article

SilverPromoted Reactions of Bicyclo321octadiene Derivatives
Dennis Wright
Research Type: Conference Proceedings

Selenium concentration of fescue and bahiagrasses after applying a selenium fertilizer
Dennis Wright
Research Type: Conference Proceedings

Selective Inhibitor of Proteasomes Caspaselike Sites Sensitizes Cells to Specific Inhibition of Chymotrypsinlike Sites
2009
Dennis Wright
Research Type: Journal Article

Ringopening metathesis polymerization with 22crosslinking to create new materials
Dennis Wright
Research Type: Conference Proceedings

Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditions
Dennis Wright
Research Type: Conference Proceedings

Recent progress on the synthesis of cyathane type diterpenes A review
Dennis Wright
Research Type: Conference Proceedings

Prospective screening of novel antibacterial inhibitors of dihydrofolate reductase for mutational resistance
2012
Dennis Wright, Amy Anderson
Research Type: Journal Article

Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis.
2016
Amy Anderson, S Reeve, Dennis Wright, J Krucinska, B Hajian, C Shoen, M Cynamon, N G-Dayanandan, S Keshipeddy, E Scocchera
Research Type: Journal Article

Propargyl linked antifolates are dual inhibitors of Candida albicans and Candida glabrata
2014
Narendarn G-Dyanan, Dennis Wright
Research Type: Poster/Presentation