Dennis Wright
Professor/Pharmaceutical Science
Storrs Mansfield
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Scholarly Contributions
132 Scholarly Contributions
Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors
2009
Research Type: Journal Article
Post-Glycosylation Diversification (PGD): An Approach for Assembling Collections of Glycosylated Small Molecules
2019
Research Type: Journal Article
Photocurable hard and porous biomaterials from ROMP precursors crosslinked with diyl radicals
Research Type: Conference Proceedings
Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse
2017
Research Type: Journal Article
Oxabicyclo321octane derivatives as highly reactive dienophiles Synthesis of bicyclo5n0 systems
Research Type: Conference Proceedings
Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis.
2016
Research Type: Journal Article
Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells.
2017
Research Type: Journal Article
Novel guanidine compounds inhibit platelet-derived growth factor receptor alpha transcription and oligodendrocyte precursor cell proliferation.
2021
Research Type: Journal Article
Nonpeptidic lysosomal modulators derived from ZPheAladiazomethylketone for treating protein accumulation diseases
2012
Research Type: Journal Article
New chiral building blocks from tetrabromocyclopropene and furan
Research Type: Conference Proceedings
Natural products in parallel synthesis Triazole libraries of nonactic acid
2008
Research Type: Journal Article
Natural product derivatives with bactericidal activity against Grampositive pathogens including methicillinresistant Staphylococcus aureus and vancomycinresistant Enterococcus faecalis
2010
Research Type: Journal Article
Natural feedstocks for diversity oriented synthesis: macrolide-like scaffolds from nonactate
2011
Research Type: Journal Article
Measuring propargyl-linked drug populations inside bacterial cells, and their interaction with a dihydrofolate reductase target, by Raman microscopy.
2015
Research Type: Journal Article
Mapping phorbol ester binding domains of protein kinase C PKC The design synthesis and biological activity of novel phorbol ester dimers
Research Type: Conference Proceedings
MRSA isolates from the United States hospitals carry dfrG and drfK resistance genes and succumb to propargyl-linked antifolates
2016
Research Type: Journal Article
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.
2016
Research Type: Journal Article