Dennis Wright
Professor/Pharmaceutical Science

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Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors
2009
Dennis Wright, Amy Anderson
Research Type: Journal Article

Preface
2005
Blair T Johnson, Dolores Albarracin, Mark P Zanna
Research Type: Book

Post-Glycosylation Diversification (PGD): An Approach for Assembling Collections of Glycosylated Small Molecules
2019
Adam Zweifach, Dennis Wright, Chris Lorenc, Santosh Keshipeddy, Victoria L. Robinson, Ala M. Shaqra, Liza Henowitz, Zachary Cannone, Mark W Peczuh
Research Type: Journal Article

Photocurable hard and porous biomaterials from ROMP precursors crosslinked with diyl radicals
Research Type: Conference Proceedings

Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse
2017
N. D. Priestley, S. Keshipeddy, J. B. Alverson, Dennis Wright, Amy Anderson, P. A. Barney, J. Hoody, L. Walker
Research Type: Journal Article

Oxabicyclo321octane derivatives as highly reactive dienophiles Synthesis of bicyclo5n0 systems
Research Type: Conference Proceedings

Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis.
2016
E R Falcone, S A Holstein, Andrew Wiemer, J Li, Amy Anderson, Dennis Wright
Research Type: Journal Article

Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells.
2017
Dennis Wright, S A Holstein, A M Aldridge, S H Colligan, C Allen, Q Hu, S L Haney, E R Falcone, M L Varney, K M Dykstra, Andrew Wiemer
Research Type: Journal Article

Novel guanidine compounds inhibit platelet-derived growth factor receptor alpha transcription and oligodendrocyte precursor cell proliferation.
2021
A Sherafat, W M Wood, S Sakya, Jingfeng Song, J Medved, Akiko Nishiyama, Dennis Wright, M D van Heyst
Research Type: Journal Article

Nonpeptidic lysosomal modulators derived from ZPheAladiazomethylketone for treating protein accumulation diseases
2012
Research Type: Journal Article

New chiral building blocks from tetrabromocyclopropene and furan
Research Type: Conference Proceedings

Natural products in parallel synthesis Triazole libraries of nonactic acid
2008
Kathleen Wells, Dennis Wright
Research Type: Journal Article

Natural product derivatives with bactericidal activity against Grampositive pathogens including methicillinresistant Staphylococcus aureus and vancomycinresistant Enterococcus faecalis
2010
Research Type: Journal Article

Natural feedstocks for diversity oriented synthesis: macrolide-like scaffolds from nonactate
2011
Nigel Priestley, P Whitney Swain, Dennis Wright, Stephen Bergmeier, Mark McMills, Yuliya Sumskaya
Research Type: Journal Article

Multivalent binding in the design of bioactive compounds
Research Type: Conference Proceedings

Measuring propargyl-linked drug populations inside bacterial cells, and their interaction with a dihydrofolate reductase target, by Raman microscopy.
2015
H Heidari-Torkabadi, P R Carey, Michael Lombardo, T Che, Dennis Wright, Amy Anderson
Research Type: Journal Article

Mapping phorbol ester binding domains of protein kinase C PKC The design synthesis and biological activity of novel phorbol ester dimers
Research Type: Conference Proceedings

MRSA isolates from the United States hospitals carry dfrG and drfK resistance genes and succumb to propargyl-linked antifolates
2016
S M Reeve, Jeffrey R Aeschlimann, Michael D Nailor, Amy Anderson, J Ferreira, J Krucinska, N G Dayanadan, B Hajjan, E W Scocchera, S Keshipeddy, Dennis Wright
Research Type: Journal Article

MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.
2016
Amy Anderson, Jeffrey R Aeschlimann, Dennis Wright, S Keshipeddy, E W Scocchera, B Hajian, J Ferreira, N G-Dayanadan, J Krucinska, S M Reeve, Michael D Nailor
Research Type: Journal Article

Intramolecular aziridination Decomposition of diazoamides with tethered imino bonds
Research Type: Conference Proceedings