Dennis Wright
Professor/Pharmaceutical Science

Are you Dennis Wright?

How to update your information.
Scholarly Contributions

132 Scholarly Contributions

68
Journal Articles
46
Conference Proceedings
14
Poster/Presentations
3
Patent and Intellectual Propertys
1
Book
Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.
2019
B Hajian, J Krucinska, A Estrada, Dennis Wright, K Viswanathan, E Scocchera, K Miku≈°ová, M Cynamon, H Erlandsen, N G-Dayanandan, J Korduláková, C Shoen
Research Type: Journal Article

Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks.
2017
E W Scocchera, S Keshipeddy, Amy Anderson, Dennis Wright, H F Jones, N G-Dayanandan
Research Type: Journal Article

Dihydrofolate reductase inhibitors Developments in antiparasitic chemotherapy
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

Development of intestinal organoids as tissue surrogates: cell composition and the epigenetic control of differentiation.
2015
Wanli Xu, Jason D Gibson, Dennis Wright, L Cao, F Kolling, 4th, A Kuratnik, M D Van Heyst, E R Falcone, M Ammar, Charles A Giardina, C E Nelson
Research Type: Journal Article

Design and synthesis of novel antifolates as potent inhibitors of Bacillus anthracis
2012
Amy Anderson, Beierlin Jennifer, Dennis Wright, Viswanathan Kishore
Research Type: Poster/Presentation

Deoxygenation/methylation of heteroaryl propargyl alcohols: Methods to generate unsubstituted, mono-, and di-methylated alkynes
2014
Dennis Wright, Narendran G-Dyanana, Eric Scocchera
Research Type: Poster/Presentation

Cyclopropene cycloadditions with annulated furans: total synthesis of (+)- and (-)-frondosin B and (+)-frondosin a
2014
E Zachary Oblak, Michael D VanHeyst, Jin Li, Dennis Wright, Andrew Wiemer
Research Type: Journal Article

Cyclopropene cycloadditions with annulated furans: Total synthesis of (+) frondosin A and (+) and (-) frondosin B
2014
Dennis Wright, Micahael VanHeyst
Research Type: Poster/Presentation

Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
2009
Dennis Wright, Michael Lombardo, Amy Anderson, D B Bolstad, J Liu, K M Frey
Research Type: Journal Article

Crystal structures of Klebsiella pneumoniae dihydrofolate reductase bound to propargyl-linked antifolates reveal features for potency and selectivity.
2014
Michael Lombardo, Amy Anderson, N D Priestley, J Alverson, Dennis Wright, K M Lamb
Research Type: Journal Article

Crystal Structures of Wildtype and Mutant Methicillinresistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternate Conformation of NADPH That May Be Linked to Trimethoprim Resistance
Amy Anderson, Michael Lombardo, Dennis Wright
Research Type: Conference Proceedings

Compounds for lysosomal modulation and methods of use
2009
Dennis Wright
Research Type: Patent and Intellectual Property

Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus.
2022
V G Fowler, S M Reeve, M S Frenkel, A A Ojewole, Dennis Wright, S Keshipeddy, B R Donald, G T Holt, P Gainza, Shuwen Wang
Research Type: Journal Article

Characterization of trimethoprim resistant E. coli dihydrofolate reductase mutants by mass spectrometry and inhibition by propargyl-linked antifolates
2017
Amy Anderson, M. Cammarata, J. S. Brodbelt, Michael Lombardo, A. Ellington, Dennis Wright, R. Thyer
Research Type: Journal Article

Chapter 1 Furans as versatile synthons for targetoriented and diversityoriented synthesis
Dennis Wright
Research Type: Conference Proceedings

Bridged Synthons from Tetrabromocyclopropene Studies on the Rearrangement of the Primary DielsAlder Adduct with 25Dimethylfuran
Dennis Wright
Research Type: Conference Proceedings

Bicyclo 321octane Synthons from Cyclopropenes Functionalization of Cycloadducts by Nucleophilic Additions
Dennis Wright
Research Type: Conference Proceedings

Azaviridins as new scaffolds for the development of PI3K inhibitors
2010
Dennis Wright
Research Type: Journal Article

Application of olefin metathesis to organic synthesis
Dennis Wright
Research Type: Conference Proceedings

Antimicrobials Targeting Central Metabolism
2020
Dennis Wright
Research Type: Poster/Presentation