Dennis Wright
Professor/Pharmaceutical Science

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Scholarly Contributions

132 Scholarly Contributions

68
Journal Articles
46
Conference Proceedings
14
Poster/Presentations
3
Patent and Intellectual Propertys
1
Book
Preface
2005
Blair T Johnson, Dolores Albarracin, Mark P Zanna
Research Type: Book

Analysis of complexes of inhibitors with Cryptosporidium hominis DHFR leads to a new trimethoprim derivative
2006
Amy Anderson, Dennis Wright
Research Type: Journal Article

Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis
2007
Amy Anderson, Dennis Wright
Research Type: Journal Article

Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase.
2008
Amy Anderson, J Liu, N D Priestley, Dennis Wright, D B Bolstad, A E Smith
Research Type: Journal Article

Natural products in parallel synthesis Triazole libraries of nonactic acid
2008
Kathleen Wells, Dennis Wright
Research Type: Journal Article

Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from cryptosporidium.
2008
Dennis Wright, K M Frey, E S Bolstad, D B Bolstad, Amy Anderson
Research Type: Journal Article

Structurebased approach to the development of potent and selective inhibitors of dihydrofolate reductase from Cryptosporidium
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

Structurebased approach to pharmacophore identification in silico screening and threedimensional quantitative structureactivity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function
2008
Dennis Wright, Amy Anderson
Research Type: Journal Article

Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
2008
Amy Anderson, S Ananthan, N Schormann, O Senkovich, K Walker, Dennis Wright, S Velu, B Shinkre, A Rosowsky, D Chattopadhyay
Research Type: Journal Article

Dihydrofolate reductase inhibitors Developments in antiparasitic chemotherapy
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

StructureGuided Development of Efficacious Antifungal Agents Targeting Candida glabrata Dihydrofolate Reductase
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans.
2009
A E Smith, D B Bolstad, Dennis Wright, N D Priestley, Amy Anderson, J L Paulsen, J Liu
Research Type: Journal Article

In vitro biological activity and structural analysis of 24diamino52arylpropargylpyrimidine inhibitors of Candida albicans
2009
Dennis Wright, Amy Anderson
Research Type: Journal Article

Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors
2009
Dennis Wright, Amy Anderson
Research Type: Journal Article

Selective Inhibitor of Proteasomes Caspaselike Sites Sensitizes Cells to Specific Inhibition of Chymotrypsinlike Sites
2009
Dennis Wright
Research Type: Journal Article

Inhibitors of phosphoinositide3kinase A structurebased approach to understanding potency and selectivity
2009
Amy Anderson, Dennis Wright
Research Type: Journal Article

Towards new antifolates targeting eukaryotic opportunistic infections
2009
Dennis Wright, Amy Anderson
Research Type: Journal Article

Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
2009
Dennis Wright, Michael Lombardo, Amy Anderson, D B Bolstad, J Liu, K M Frey
Research Type: Journal Article

Inhibitors of phosphoinositide-3-kinase: a structure-based approach to understanding potency and selectivity.
2009
Amy Anderson, Dennis Wright, T J Sundstrom
Research Type: Journal Article

Compounds for lysosomal modulation and methods of use
2009
Dennis Wright
Research Type: Patent and Intellectual Property