Dennis Wright
Professor/Pharmaceutical Science

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Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase.
2010
K M Frey, Michael Lombardo, Amy Anderson, Dennis Wright
Research Type: Journal Article

Natural product derivatives with bactericidal activity against Grampositive pathogens including methicillinresistant Staphylococcus aureus and vancomycinresistant Enterococcus faecalis
2010
Research Type: Journal Article

Azaviridins as new scaffolds for the development of PI3K inhibitors
2010
Research Type: Journal Article

Tandem Metathesis Reactions of Oxabicyclo[2.2.1]heptenes: Studies on the Spirocyclic Core of Cyclopamine
2011
Naren Dayanandan, Dennis Wright, Edward Oblak
Research Type: Journal Article

Antifolate agents: a patent review (2006 - 2010).
2011
Amy Anderson, Dennis Wright
Research Type: Journal Article

Highly Substituted Oxabicyclic Derivatives from Furan: Synthesis of (±)-Platensimycin
2011
Dennis Wright, Edward Oblak
Research Type: Journal Article

Antifolate Agents: A Patent Review (2006-2011)
2011
Dennis Wright, Amy Anderson
Research Type: Journal Article

Natural feedstocks for diversity oriented synthesis: macrolide-like scaffolds from nonactate
2011
Nigel Priestley, P Whitney Swain, Dennis Wright, Stephen Bergmeier, Mark McMills, Yuliya Sumskaya
Research Type: Journal Article

Acetylenic linkers in lead compounds A study of the stability of the propargyllinked antifolates
2012
Dennis Hill, Wangda Zhou, Amy Anderson, Kishore Viswanathan, Dennis Wright
Research Type: Journal Article

Acetylenic linkers in lead compounds: a study of the stability of the propargyl-linked antifolates.
2012
K Viswanathan, W Zhou, Dennis Hill, Amy Anderson, Dennis Wright
Research Type: Journal Article

Synthesis of a functionalized oxabicyclo221heptenebased chemical library
2012
Research Type: Journal Article

Viridin analogs derived from steroidal building blocks
2012
Dennis Wright, Amy Anderson
Research Type: Journal Article

Nonpeptidic lysosomal modulators derived from ZPheAladiazomethylketone for treating protein accumulation diseases
2012
Research Type: Journal Article

Toward new Therapeutics for Skin and Soft Tissue Infections: Propargyl-linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes
2012
Brooke Martin, Dennis Wright, Eric Scocchera, Amy Anderson, Jeremy Alverson, Nigel Priestley, P Swain, Kathleen Frey, Kishore Viswanathan
Research Type: Journal Article

Prospective screening of novel antibacterial inhibitors of dihydrofolate reductase for mutational resistance
2012
Dennis Wright, Amy Anderson
Research Type: Journal Article

The furan route to tropolones Probing the antiproliferative effects of thujaplicin analogs
2012
Research Type: Journal Article

Furan Derived Building Blocks for Natural Products
2012
Research Type: Poster/Presentation

Design and synthesis of novel antifolates as potent inhibitors of Bacillus anthracis
2012
Amy Anderson, Beierlin Jennifer, Dennis Wright, Viswanathan Kishore
Research Type: Poster/Presentation

Inhibitors of DHFR as New Antimicrobials
2012
Research Type: Poster/Presentation

Heterocycles in Drug Discovery
2012
Research Type: Poster/Presentation