Dennis Wright
Professor/Pharmaceutical Science

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Cyclopropene cycloadditions with annulated furans: Total synthesis of (+) frondosin A and (+) and (-) frondosin B
2014
Dennis Wright, Micahael VanHeyst
Research Type: Poster/Presentation

The tandem ring openingring closing metathesis route to oxaspirocycles An approach to phelligridin G
2013
Research Type: Journal Article

Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligandinduced conformational changes shared among species
2013
Janet Paulsen, Amy Anderson, Kishore Viswanathan, Dennis Wright
Research Type: Journal Article

Tropolones as lead-like natural products: the development of potent and selective histone deacetylase inhibitors.
2013
M Ammar, Amy Anderson, Dennis Wright, W Zhou, E Z Oblak, S N Ononye, M D VanHeyst
Research Type: Journal Article

Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species.
2013
Amy Anderson, J L Paulsen, Dennis Wright, K Viswanathan
Research Type: Journal Article

Inhibitors of Dihydrofolate Reductase with Antibacterial, Antiprotozoal, Antifungal and Anticancer Properties
2013
Research Type: Patent and Intellectual Property

Acetylenic linkers in lead compounds A study of the stability of the propargyllinked antifolates
2012
Dennis Hill, Wangda Zhou, Amy Anderson, Kishore Viswanathan, Dennis Wright
Research Type: Journal Article

Acetylenic linkers in lead compounds: a study of the stability of the propargyl-linked antifolates.
2012
K Viswanathan, W Zhou, Dennis Hill, Amy Anderson, Dennis Wright
Research Type: Journal Article

Synthesis of a functionalized oxabicyclo221heptenebased chemical library
2012
Research Type: Journal Article

Viridin analogs derived from steroidal building blocks
2012
Dennis Wright, Amy Anderson
Research Type: Journal Article

Nonpeptidic lysosomal modulators derived from ZPheAladiazomethylketone for treating protein accumulation diseases
2012
Research Type: Journal Article

Toward new Therapeutics for Skin and Soft Tissue Infections: Propargyl-linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes
2012
Brooke Martin, Dennis Wright, Eric Scocchera, Amy Anderson, Jeremy Alverson, Nigel Priestley, P Swain, Kathleen Frey, Kishore Viswanathan
Research Type: Journal Article

Prospective screening of novel antibacterial inhibitors of dihydrofolate reductase for mutational resistance
2012
Dennis Wright, Amy Anderson
Research Type: Journal Article

The furan route to tropolones Probing the antiproliferative effects of thujaplicin analogs
2012
Research Type: Journal Article

Furan Derived Building Blocks for Natural Products
2012
Research Type: Poster/Presentation

Design and synthesis of novel antifolates as potent inhibitors of Bacillus anthracis
2012
Amy Anderson, Beierlin Jennifer, Dennis Wright, Viswanathan Kishore
Research Type: Poster/Presentation

Inhibitors of DHFR as New Antimicrobials
2012
Research Type: Poster/Presentation

Heterocycles in Drug Discovery
2012
Research Type: Poster/Presentation

Tandem Metathesis Reactions of Oxabicyclo[2.2.1]heptenes: Studies on the Spirocyclic Core of Cyclopamine
2011
Naren Dayanandan, Dennis Wright, Edward Oblak
Research Type: Journal Article

Antifolate agents: a patent review (2006 - 2010).
2011
Amy Anderson, Dennis Wright
Research Type: Journal Article