Dennis Wright
Professor/Pharmaceutical Science

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Scholarly Contributions

132 Scholarly Contributions

68
Journal Articles
46
Conference Proceedings
14
Poster/Presentations
3
Patent and Intellectual Propertys
1
Book
Highly Substituted Oxabicyclic Derivatives from Furan: Synthesis of (±)-Platensimycin
2011
Dennis Wright, Edward Oblak
Research Type: Journal Article

Antifolate Agents: A Patent Review (2006-2011)
2011
Dennis Wright, Amy Anderson
Research Type: Journal Article

Natural feedstocks for diversity oriented synthesis: macrolide-like scaffolds from nonactate
2011
Nigel Priestley, P Whitney Swain, Dennis Wright, Stephen Bergmeier, Mark McMills, Yuliya Sumskaya
Research Type: Journal Article

Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase.
2010
K M Frey, Michael Lombardo, Amy Anderson, Dennis Wright
Research Type: Journal Article

Natural product derivatives with bactericidal activity against Grampositive pathogens including methicillinresistant Staphylococcus aureus and vancomycinresistant Enterococcus faecalis
2010
Dennis Wright
Research Type: Journal Article

Azaviridins as new scaffolds for the development of PI3K inhibitors
2010
Dennis Wright
Research Type: Journal Article

In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans.
2009
A E Smith, D B Bolstad, Dennis Wright, N D Priestley, Amy Anderson, J L Paulsen, J Liu
Research Type: Journal Article

In vitro biological activity and structural analysis of 24diamino52arylpropargylpyrimidine inhibitors of Candida albicans
2009
Dennis Wright, Amy Anderson
Research Type: Journal Article

Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors
2009
Dennis Wright, Amy Anderson
Research Type: Journal Article

Selective Inhibitor of Proteasomes Caspaselike Sites Sensitizes Cells to Specific Inhibition of Chymotrypsinlike Sites
2009
Dennis Wright
Research Type: Journal Article

Inhibitors of phosphoinositide3kinase A structurebased approach to understanding potency and selectivity
2009
Amy Anderson, Dennis Wright
Research Type: Journal Article

Towards new antifolates targeting eukaryotic opportunistic infections
2009
Dennis Wright, Amy Anderson
Research Type: Journal Article

Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
2009
Dennis Wright, Michael Lombardo, Amy Anderson, D B Bolstad, J Liu, K M Frey
Research Type: Journal Article

Inhibitors of phosphoinositide-3-kinase: a structure-based approach to understanding potency and selectivity.
2009
Amy Anderson, Dennis Wright, T J Sundstrom
Research Type: Journal Article

Compounds for lysosomal modulation and methods of use
2009
Dennis Wright
Research Type: Patent and Intellectual Property

Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase.
2008
Amy Anderson, J Liu, N D Priestley, Dennis Wright, D B Bolstad, A E Smith
Research Type: Journal Article

Natural products in parallel synthesis Triazole libraries of nonactic acid
2008
Kathleen Wells, Dennis Wright
Research Type: Journal Article

Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from cryptosporidium.
2008
Dennis Wright, K M Frey, E S Bolstad, D B Bolstad, Amy Anderson
Research Type: Journal Article

Structurebased approach to the development of potent and selective inhibitors of dihydrofolate reductase from Cryptosporidium
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

Structurebased approach to pharmacophore identification in silico screening and threedimensional quantitative structureactivity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function
2008
Dennis Wright, Amy Anderson
Research Type: Journal Article