Dennis Wright
Professor/Pharmaceutical Science
Storrs Mansfield
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Scholarly Contributions
132 Scholarly Contributions
Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
2008
Research Type: Journal Article
Dihydrofolate reductase inhibitors Developments in antiparasitic chemotherapy
2008
Research Type: Journal Article
StructureGuided Development of Efficacious Antifungal Agents Targeting Candida glabrata Dihydrofolate Reductase
2008
Research Type: Journal Article
Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis
2007
Research Type: Journal Article
Analysis of complexes of inhibitors with Cryptosporidium hominis DHFR leads to a new trimethoprim derivative
2006
Research Type: Journal Article
Photocurable hard and porous biomaterials from ROMP precursors crosslinked with diyl radicals
Research Type: Conference Proceedings
Annulated heterocycles through a radicalcation cyclization synthetic and mechanistic studies
Research Type: Conference Proceedings
Altered specificity of HintW123Q supports a role for Hint inhibition by ASW in avian sex determination
Research Type: Conference Proceedings
Crystal Structures of Wildtype and Mutant Methicillinresistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternate Conformation of NADPH That May Be Linked to Trimethoprim Resistance
Research Type: Conference Proceedings
Electrochemical annulation of fivemembered rings through dearomatization of furans and thiophenes
Research Type: Conference Proceedings
Selenium concentration of fescue and bahiagrasses after applying a selenium fertilizer
Research Type: Conference Proceedings
Chapter 1 Furans as versatile synthons for targetoriented and diversityoriented synthesis
Research Type: Conference Proceedings
Synthesis of functionalized pyrans by domino metathesis reaction of oxabicyclo derivatives Dramatic effect of remote substituents on reactivity and selectivity
Research Type: Conference Proceedings
Facile generation of aziridines from the reaction of diazoamides with tethered oximinoethers
Research Type: Conference Proceedings
Towards the understanding of resistance mechanisms in clinically isolated trimethoprimresistant methicillinresistant Staphylococcus aureus dihydrofolate reductase
Research Type: Conference Proceedings
Halogenated oxabicyclo321octadiene building blocks Elaboration of the dibromoenone
Research Type: Conference Proceedings
Studies on the DielsAlder reaction of annulated furans Application to the synthesis of substituted phenanthrenes
Research Type: Conference Proceedings
Oxabicyclo321octane derivatives as highly reactive dienophiles Synthesis of bicyclo5n0 systems
Research Type: Conference Proceedings