Dennis Wright
Professor/Pharmaceutical Science

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Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
2008
Amy Anderson, S Ananthan, N Schormann, O Senkovich, K Walker, Dennis Wright, S Velu, B Shinkre, A Rosowsky, D Chattopadhyay
Research Type: Journal Article

Dihydrofolate reductase inhibitors Developments in antiparasitic chemotherapy
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

StructureGuided Development of Efficacious Antifungal Agents Targeting Candida glabrata Dihydrofolate Reductase
2008
Amy Anderson, Dennis Wright
Research Type: Journal Article

Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis
2007
Amy Anderson, Dennis Wright
Research Type: Journal Article

Analysis of complexes of inhibitors with Cryptosporidium hominis DHFR leads to a new trimethoprim derivative
2006
Amy Anderson, Dennis Wright
Research Type: Journal Article

Preface
2005
Blair T Johnson, Dolores Albarracin, Mark P Zanna
Research Type: Book

Photocurable hard and porous biomaterials from ROMP precursors crosslinked with diyl radicals
Research Type: Conference Proceedings

Annulated heterocycles through a radicalcation cyclization synthetic and mechanistic studies
Research Type: Conference Proceedings

Altered specificity of HintW123Q supports a role for Hint inhibition by ASW in avian sex determination
Research Type: Conference Proceedings

Crystal Structures of Wildtype and Mutant Methicillinresistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternate Conformation of NADPH That May Be Linked to Trimethoprim Resistance
Amy Anderson, Michael Lombardo, Dennis Wright
Research Type: Conference Proceedings

Electrochemical annulation of fivemembered rings through dearomatization of furans and thiophenes
Research Type: Conference Proceedings

Selenium concentration of fescue and bahiagrasses after applying a selenium fertilizer
Research Type: Conference Proceedings

Chapter 1 Furans as versatile synthons for targetoriented and diversityoriented synthesis
Research Type: Conference Proceedings

Synthesis of functionalized pyrans by domino metathesis reaction of oxabicyclo derivatives Dramatic effect of remote substituents on reactivity and selectivity
Research Type: Conference Proceedings

Facile generation of aziridines from the reaction of diazoamides with tethered oximinoethers
Research Type: Conference Proceedings

Towards the understanding of resistance mechanisms in clinically isolated trimethoprimresistant methicillinresistant Staphylococcus aureus dihydrofolate reductase
Amy Anderson, Michael Lombardo, Dennis Wright
Research Type: Conference Proceedings

Halogenated oxabicyclo321octadiene building blocks Elaboration of the dibromoenone
Research Type: Conference Proceedings

Studies on the DielsAlder reaction of annulated furans Application to the synthesis of substituted phenanthrenes
Research Type: Conference Proceedings

Oxabicyclo321octane derivatives as highly reactive dienophiles Synthesis of bicyclo5n0 systems
Research Type: Conference Proceedings

Unusual influence of substituents on ringopening metathesis reactions
Research Type: Conference Proceedings