Dennis Wright
Professor/Pharmaceutical Science

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Scholarly Contributions

132 Scholarly Contributions

68
Journal Articles
46
Conference Proceedings
14
Poster/Presentations
3
Patent and Intellectual Propertys
1
Book
HMGB2 is a potential diagnostic marker and therapeutic target for liver fibrosis and cirrhosis.
2023
Yen Chih Huang, N Huda, Antonio P Costa, Dennis Wright, S K Keshipeddy, J Ma, Diane J Burgess, S Rudraiah, Y Zhang, L Wang, Zhihong Yang, S Liangpunsakul
Research Type: Journal Article

Two-Metal Ion-Dependent Enzymes as Potential Antiviral Targets in Human Herpesviruses.
2022
S Weerasooriya, Lee Wright, A Hazeen, K A DiScipio, S K Weller, Dennis Wright, R Szczepaniak
Research Type: Journal Article

Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus.
2022
V G Fowler, S M Reeve, M S Frenkel, A A Ojewole, Dennis Wright, S Keshipeddy, B R Donald, G T Holt, P Gainza, Shuwen Wang
Research Type: Journal Article

Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
2022
Dennis Wright, A Estrada, J Krucinska, H Erlandsen, K Viswanathan, D Si, Michael Lombardo
Research Type: Journal Article

Novel guanidine compounds inhibit platelet-derived growth factor receptor alpha transcription and oligodendrocyte precursor cell proliferation.
2021
A Sherafat, W M Wood, S Sakya, Jingfeng Song, J Medved, Akiko Nishiyama, Dennis Wright, M D van Heyst
Research Type: Journal Article

Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.
2019
A Hazeen, H Erlandsen, Michael Lombardo, J G Pattis, J Krucinska, Eric May, S S Duay, Dennis Wright, Victoria L Robinson
Research Type: Journal Article

Post-Glycosylation Diversification (PGD): An Approach for Assembling Collections of Glycosylated Small Molecules
2019
Adam Zweifach, Dennis Wright, Chris Lorenc, Santosh Keshipeddy, Victoria L. Robinson, Ala M. Shaqra, Liza Henowitz, Zachary Cannone, Mark W Peczuh
Research Type: Journal Article

Structure guided in-vitro to in-vivo pharmacokinetic optimization of propargyl-linked antifolates.
2019
N Priestley, P Barney, J Hoody, D Si, L Walker, S M Reeve, Dennis Wright, W Zhou, Michael Lombardo, R S Obach, N G-Dayanandan, J Alverson, S Keshipeddy
Research Type: Journal Article

Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.
2019
B Hajian, J Krucinska, A Estrada, Dennis Wright, K Viswanathan, E Scocchera, K Miku≈°ová, M Cynamon, H Erlandsen, N G-Dayanandan, J Korduláková, C Shoen
Research Type: Journal Article

Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus.
2019
N D Gibson, J Krucinska, S S Agabiti, Y Yan, D Si, M S Frenkel, A Estrada, G T Holt, J B Alverson, S M Reeve, K Viswanathan, N D Priestley, A A Ojewole, B R Donald, Andrew Wiemer, Dennis Wright, S Wang
Research Type: Journal Article

Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
2019
Michael Lombardo, H Erlandsen, Victoria L Robinson, Dennis Wright, J Krucinska, E Falcone, A Estrada, A Hazeen, Amy Anderson
Research Type: Journal Article

Tropolone-induced effects on the unfolded protein response pathway and apoptosis in multiple myeloma cells are dependent on iron.
2019
S L Haney, G Talmon, Y S Chhonker, N G-Dayanandan, D J Murry, H R Safranek, Andrew Wiemer, Dennis Wright, M L Varney, S A Holstein
Research Type: Journal Article

Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound
2018
M. J. Bond, N. G-Dayanan, S. Keshipeddy, Dennis Wright, D. W. Rosenberg, M. Bleiler, L. E. Harrison, E. W. Scocchera, Charles A Giardina, M. Nakanishi
Research Type: Journal Article

The exonuclease activity of HSV-1 UL12 is required for the production of viral DNA that can be packaged to produce infectious virus
2017
L. M. Grady, S. K. Weller, R. Szczepaniak, Dennis Wright, R. P. Murelli, T. Masaoka
Research Type: Journal Article

Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse
2017
N. D. Priestley, S. Keshipeddy, J. B. Alverson, Dennis Wright, Amy Anderson, P. A. Barney, J. Hoody, L. Walker
Research Type: Journal Article

Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks.
2017
E W Scocchera, S Keshipeddy, Amy Anderson, Dennis Wright, H F Jones, N G-Dayanandan
Research Type: Journal Article

The Exonuclease Activity of Herpes Simplex Virus 1 UL12 Is Required for Production of Viral DNA That Can Be Packaged To Produce Infectious Virus.
2017
T Masaoka, R P Murelli, R Szczepaniak, L M Grady, S K Weller, Dennis Wright
Research Type: Journal Article

High-mobility-group protein 2 regulated by microRNA-127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells
2017
R. Wu, Dennis Wright, Li Wang, Y. Zhao, Zhihong Yang, J. Wu, S. K. Keshipeddy
Research Type: Journal Article

USP7-Specific Inhibitors Target and Modify the Enzyme's Active Site via Distinct Chemical Mechanisms
2017
P. Nguyen, J. Wu, I. Bezsonova, Kamal Kumar, D. E. Sterner, FEI WANG, G. Valles, A. Pozhidaeva, Dennis Wright, J. Weinstock, J. Kanyo
Research Type: Journal Article

Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells.
2017
Dennis Wright, S A Holstein, A M Aldridge, S H Colligan, C Allen, Q Hu, S L Haney, E R Falcone, M L Varney, K M Dykstra, Andrew Wiemer
Research Type: Journal Article