Grants
24 Grants
Achieving enhanced cytosolic delivery and greater efficacy of therapeutic nucleic acids using DNA-surfactant conjugates
Sponsor: DHHS/NIH/National Institute of General Medical Sciences
Authors: Jessica Rouge
Funding: $2,000,300
2020-08-01 - 2025-07-31
CAREER: Multi-stimuli Responsive DNA-Nanoshells - Compartmentalizing Molecules at the Nanoscale for Enhanced Reaction Selectivity and Sensitivity
Sponsor: NSF/MPS/Directorate for Mathematical and Physical Sciences
Authors: Jessica Rouge
Funding: $632,374
2019-07-15 - 2024-06-30
Design and Synthesis of a Nucleic Acid Nanocapsule Combination Vaccine
Sponsor: Merck
Authors: Jessica Rouge
Funding: $392,581
2025-03-19 - 2027-01-31
Antisense Oligonucleotide Nucleic Acid Nanocapsule therapeutics for targeted delivery and treatment of Gastrointenstinal Diseases
Sponsor: Janssen Pharmaceuticals
Authors: Jessica Rouge
Funding: $301,526
2018-12-19 - 2021-07-22
Determining the pharmacology of a novel DNAzyme-therapeutic formulation for the treatment of allergic airway disease
Sponsor: OVPR-REP
Authors: Jessica Rouge, Steven Szczepanek
Funding: $75,000
2019-05-01 - 2020-06-30
REP: Catch and release of nucleic acids with porous nanocapsules
Sponsor: University of Connecticut
Authors: Evgueni Pinkhassik, Jessica Rouge
Funding: $50,000
2018-06-01 - 2019-06-30
Visualizing the synthesis and assembly of RNA and DNA nanostructures Using in situ Liquid Cell TEM
Sponsor: OVPR-REP
Authors: Jessica Rouge, Lucas Parent
Funding: $50,000
2019-05-01 - 2019-06-30
Novel Targeted Nucleic Acid Nonocapsule-Delivered Therapeutics for Treating Optic Neuropathies
Sponsor: Connecticut Innovations/Yale University
Authors: Jessica Rouge
Funding: $10,000
2018-02-05 - 2018-12-17
Summer Undergraduate Research Fellowship (SURF) Grant for Halle Barber
Sponsor: Office of Undergraduate Research
Authors: Jessica Rouge
Funding: $4,000
2019-07-31 - 2019-08-31
Summer Undergraduate Research Fund (SURF) For Emily Saccuzzo
Sponsor: Office of Undergraduate Research
Authors: Jessica Rouge
Funding: $4,000
2017-06-30 - 2017-08-31
Chemically Programmable Chimeric Surfactants for Protein Assembly and Degradation at the Nanoscale
Sponsor: NSF/National Science Foundation
Authors: Jessica Rouge
2025-05-01 - 2028-04-30
Isolation of Ribonucleic Acid-Heme Conjugates Capable of Photocatalytic Oxidation of Sulfur-Containing Hydrocrabrons in Co-Solvent Systems
Sponsor: American Chemical Society/Petroleum Research Fund
Authors: Jessica Rouge
2019-07-01 - 2021-08-31
Development of novel surfactant-DNA conjugate nanoparticles for targeted therapeutic regulation of proinflammatory genes
Sponsor: DHHS/NIH/National Institutes of Health
Authors: Jessica Rouge
2022-09-01 - 2027-08-31
Nucleic Acid Nanocapsules as Biochemically Responsive Drug Delivery Vehicles
Sponsor: NSF/National Science Foundation
Authors: Jessica Rouge
2017-08-01 - 2020-07-31
CAREER: DNA Programmable Peptide-Crosslinked Nanocapsules: Delivering Cargos to Cells and Research Experiences to High School Students
Sponsor: NSF/National Science Foundation
Authors: Jessica Rouge
2018-05-01 - 2023-04-30
A novel approach for codelivery of a small molecule drug and therapeutic oligonucleotide for regulating lung inflammatory disease
Sponsor: Pharmaceutical Research & Manufacturers of America (PhRMA) Foundation
Authors: Jessica Rouge
2021-01-01 - 2022-12-31
Homing in on Cancer: Leveraging In Vitro Selection to Improve the Targeting of Nanomaterlal-Based Therapeutics Into Cancer Cells
Sponsor: DHHS/NIH/National Institutes of Health
Authors: Jessica Rouge
2017-07-01 - 2022-06-30
Enhancing Therapeutic efficacy using multi-gene silencing RNA nanoconjugates
Sponsor: Johnson & Johnson
Authors: Jessica Rouge
2019-05-01 - 2022-04-30
Isolation of Ribonucleic Acid-Heme Conjugates Capable of Photocatalytic Oxidation of Sulfur-Containing Hydrocarbons in Co-Solvent Systems
Sponsor: American Chemical Society
Authors: Jessica Rouge
2018-09-01 - 2020-08-31
Hybrid Nucleic Acid Nanocapsules for the Targeted Delivery of a GATA-3 Specific DNAzymes and Anti-Inflammatory Agents to Bronchial Epithelial Cells
Sponsor: American Asthma Foundation
Authors: Jessica Rouge
2016-08-01 - 2017-07-31
Retinal ganglion cell-targeted nanocapsule for sustained regeneration for injured axonal tissue
Sponsor: DOD/Department of Defense/University of Connecticut Health Center
Authors: Jessica Rouge
2019-09-01 - 2021-02-28
Homing in on Cancer: A Novel Form of In Vitro Selection for Improving the Targeting of Nanomaterial-Based Therapeutics into Cancer Cells
Sponsor: Damon Runyon Cancer Research Foundation
Authors: Jessica Rouge
2017-01-01 - 2019-12-31
Photocatalytic Oxidation of Sulfur-Containing Hydrocarbons by a Biomimetic RNA-Ti02 Nanoparticle Conjugate
Sponsor: American Chemical Society/Petroleum Research Fund
Authors: Jessica Rouge
2016-09-01 - 2018-08-30
Development of Novel Surfactant-DNA Conjugate Nanocapsules for Targeted Therapeutic Regulation of Proinflammatory Genes
Sponsor: DHHS/NIH/National Institutes of Health
Authors: Jessica Rouge
2019-09-01 - 2024-08-31