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Polymer-based Nanocarrier Platform for Improving Efficacy and Safety of Potent Chemotherapeutic Agents

Sponsor: UConn Academic Plan Grant

Authors: Xiuling Lu, Rajeswari Kasi, Bruce Liang, Jose E Manautou, Ming-Hui Chen

Funding: $240,000

2015-07-01 - 2018-06-30

A metabolomics-based laboratory developed test to help diagnose drug-induced liver injury

Sponsor: DHHS/NIH/National Institutes of Health/Metabolon GmbH

Authors: Jose E Manautou

2024-07-01 - 2025-06-30

A highly accurate diagnostic test for drug induced liver injury

Sponsor: DHHS/NIH/National Institutes of Health/Metabolon GmbH

Authors: Jose E Manautou

2022-12-01 - 2023-11-30

Regulation of Hepatic Transporter Expression by Inflammatory Mediators During Drug-Induced Liver Injury.

Sponsor: Pharmaceutical Research & Manufacturers of America (PhRMA) Foundation

Authors: Jose E Manautou

Funding: $40,000

2006-07-01 - 2008-06-30

Multidrug Resistance-associate Protein 4 (Mrp4/ABCC4), a Novel Contributor to Non-Alcoholic Fatty Liver Disease Development

Sponsor: DHHS/NIH/National Institutes of Health

Authors: Jose E Manautou

2020-07-01 - 2025-06-30

Use of Diversity Outbred Mice to Study Cardiotoxicity of Chemotherapeutic Agents

Sponsor: University of Connecticut Health Center

Authors: Jose E Manautou

Funding: $35,830

2013-10-01 - 2018-09-30

Connecticut Environmental Health Sciences Core Center (CTEHSC)

Sponsor: DHHS/NIH/National Institute of Environmental Health Sciences/Yale University

Authors: Jose E Manautou

2025-04-01 - 2029-03-31

Transporter Expression in Response to Hepatotoxicants

Sponsor: DHHS/NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Authors: Jose E Manautou

2004-12-01 - 2009-11-30

Transporter Expression in Response to Hepatotoxicants

Sponsor: DHHS/NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Authors: Jose E Manautou

Funding: $1,312,775

2010-09-20 - 2014-06-30

Drug-induced liver injury with medications used in the COVID-19 pandemic

Sponsor: DHHS/NIH/National Institutes of Health

Authors: Jose E Manautou

2021-04-01 - 2026-03-31

Role of Kupffer Cells and Cytokines in the Regulation of Liver Transporters During Acetaminophen Hepatotoxicity

Sponsor: DHHS/NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Authors: Jose E Manautou

2007-12-01 - 2009-11-30

Gender-Related Differences in Susceptibility to Hepatotoxicity in Mice: Possible Pathways Involved

Sponsor: American Foundation for Pharmaceutical Education

Authors: Jose E Manautou

2013-09-01 - 2014-08-31

Role of Kupffer Cells and Cytokines in the Regulation of Liver Transporters

Sponsor: DHHS/NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Authors: Jose E Manautou

2008-07-01 - 2010-06-30

Drug Transporters in the Pathogenesis of Non-Alcoholic Fatty Liver Disease during Liver Regeneration Processes

Sponsor: DHHS/NIH/National Institutes of Health

Authors: Jose E Manautou

2018-09-01 - 2023-08-31

Mechanistic Involvement of Vanin-1 in Protection Against Acetaminophen Hepatotoxicity

Sponsor: Pharmaceutical Research & Manufacturers of America (PhRMA) Foundation

Authors: Jose E Manautou

2011-01-01 - 2012-12-31

Mechanistic Involvement of Vanin-1 in the Protection Against Paracetamol Hepatotoxicity

Sponsor: French Embassy in Washington, D.C.

Authors: Jose E Manautou

2011-09-01 - 2012-02-28

Drug Transporters, Kupffer Cells and Acetaminophen Hepatotoxicity

Sponsor: DHHS/NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Authors: Jose E Manautou

2009-09-30 - 2011-09-29

Use of Diversity Outbred Mice to Study Cardiotoxicity of Chemotherapeutic Agents

Sponsor: American Heart Association/Connecticut Children's Medical Center

Authors: Jose E Manautou

2014-07-01 - 2017-06-30

Transcriptional Regulation of Hepatic Inflammation by Green Tea Extract in Rodent Models of Oxidative Stress

Sponsor: USDA/National Institute of Food and Agriculture/Ohio State University

Authors: Jose E Manautou

Funding: $10,797

2015-02-01 - 2016-01-31

Transporter Expression in Response to Hepatotoxicants

Sponsor: DHHS/NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Authors: Jose E Manautou

Funding: $1,105,721

2005-09-30 - 2011-01-31

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