Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Scholarly Contributions

186 Scholarly Contributions

118
Poster/Presentations
59
Journal Articles
8
Other Scholarly Works
1
Book Chapter
Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin
2024
Prajith Stephen, Jordyn Belcourt, Alexis Frankel, Alicia Zongxun Wang, Sherouk M. Tawfik, Milan Shah, Theodore Rasmussen, Xiao Bo Zhong, Jing Jin, Anagha Gogate, Jose E Manautou, Aarush Kolli, Raman Bahal, Matthew Chalon, Holly Kolmel
Research Type: Other Scholarly Work

Impact of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) on the expression and function of hepatobiliary transporters: A comprehensive mechanistic review
2024
Ankit P. Laddha, Raymond Xue, José E. Manautou, Cedric Lewis, Lindsey Dzielak
Research Type: Other Scholarly Work

Faculty expectations and their management: The UConn school of pharmacy experience
2024
Jose E Manautou
Research Type: Poster/Presentation

A holistic analysis of the intrinsic and delivery-mediated toxicity of siRNA therapeutics.
2023
Jose E Manautou, xiaobo zhong, Xiuling Lu, Sheyda Ranjbar
Research Type: Journal Article

Multivalent Lactobionic Acid and N-Acetylgalactosamine-Conjugated Peptide Nucleic Acids for Efficient In Vivo Targeting of Hepatocytes
2023
Anisha Gupta, José E. Manautou, Vikas Kumar, Aniket Wahane, Raman Bahal
Research Type: Journal Article

Multidrug Resistance Protein-4 (Mrp4) at the Intersection of the Liver-Adipose Tissue Axis”, Belgrade, Serbia, May 30, 2023 (plenary talk)
2023
Jose E Manautou
Research Type: Poster/Presentation

La proteina asociada a resistencia a multiples farmacos tipo 4 (ABCC4/MRP4) se perfila como un nuevo determinante genetico del la enfermedad de higado graso no alcoholico (NAFLD)
2023
Jose E Manautou
Research Type: Poster/Presentation

The beauty of toxicology: When a drug-induced liver injury project becomes a metabolic syndrome, adiposity and diabetes line of investigation
2023
Jose E Manautou
Research Type: Poster/Presentation

La proteína asociada a resistencia a múltiples fármacos tipo 4 (ABCC4/MRP4), además de ser un modulador de la toxicidad de fármacos, es un factor determinante en el desarrollo de la enfermedad de hígado graso no alcohólico.
2023
Jose E Manautou
Research Type: Poster/Presentation

Mechanistic toxicity of FDA-approved ASO and siRNA drugs
2023
Jose E Manautou
Research Type: Poster/Presentation

Uncovering new functions of ABC transporter Multidrug resistance protein 4 (MRP4/ABCC4) beyond its well-documented in drug efflux: The link between MRP4 and metabolic syndrome”, Guangzhou, China, November 11, 2023.
2023
Jose E Manautou
Research Type: Poster/Presentation

Nephrotoxicity of marketed antisense oligonucleotide drugs
2022
Feryal Alhamadani, Rajvi Parikh, Theodore Rasmussen, Evan M McCabe, SooWan Lee, Xiaobo Zhong, Jose E Manautou, Aniket Wahane, Hangyu Wu, Raman Bahal, Kristy Zhang
Research Type: Journal Article

Adverse Drug Reactions and Toxicity of the Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
2022
Kristy Zhang, Hangyu Wu, Rajvi Parikh, xiaobo zhong, Theodore Rasmussen, Feryal Alhamadani, Jose E Manautou, Raman Bahal
Research Type: Journal Article

Casimersen for the treatment of Duchenne muscular dystrophy.
2022
Raman Bahal, S P Pradeep, Jose E Manautou, V Kasina, A P Laddha, S E Zakeri
Research Type: Journal Article

Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
2022
Sunna Liu, xiaobo zhong, Sreenidhi Nair, Theodore Rasmussen, Anna Liu, Anagha Gogate, Raman Bahal, Julia M Migliorati, Jose E Manautou
Research Type: Journal Article

Alterations of cytochrome P450-mediated drug metabolism during liver repair and regeneration after acetaminophen-induced liver injury in mice
2022
Yifan Bao, Xiaochao Ma, Jose E Manautou, Mi Phan, Junjie Zhu, xiaobo zhong
Research Type: Journal Article

Editorial overview: New cause for concern–Emerging nephrotoxicants and mechanisms of renal injury
2022
José E. Manautou, Lauren M. Aleksunes, Gary O. Rankin
Research Type: Other Scholarly Work

Nedosiran, a Candidate siRNA Drug for the Treatment of Primary Hyperoxaluria: Design, Development, and Clinical Studies
2022
Theodore Rasmussen, Jenny Zhao, Julia M. Migliorati, Raman Bahal, Jose E Manautou, Milan Shah, Anna Liu, Sherouk M. Tawfik, Xiao Bo Zhong
Research Type: Other Scholarly Work

Rethinking Subthreshold Effects in Regulatory Chemical Risk Assessments
2022
Takayoshi Koike, Olga Ioanna Kalantzi, Stephen O. Duke, Manish Kumar, Alessandra De Marco, Vasileios Fotopoulos, Aristidis Tsatsakis, Yolanda Picó, Pierre Sicard, Ivo Iavicoli, José E. Manautou, Raul Narciso Guedes, Elena Paoletti, A. Wallace Hayes, Wenjie Wang, Michael N. Moore, Despo Fatta-Kassinos, Ricardo Antunes Azevedo, G. Christopher Cutler, Anca Oana Docea, Josep Peñuelas, Alexander I. Vardavas, David Costantini, Teresa Rocha-Santos, Edward J. Calabrese, Christian Sonne, Jörg Rinklebe, Ramin Rezaee, Demetrios Kouretas, Michael Aschner, Evgenios Agathokleous, Christopher Teaf, Prosun Bhattacharya, José G. Dórea, Russel J. Reiter, Dami√† Barceló, Thomas Efferth, Antonio Ginebreda, Eddy Y. Zeng
Research Type: Other Scholarly Work

Role and Regulation of Hepatobiliary ATP-Binding Cassette Transporters during Chemical-Induced Liver Injury
2022
Carolina I. Ghanem, Jose E Manautou
Research Type: Other Scholarly Work