Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Scholarly Contributions

186 Scholarly Contributions

118
Poster/Presentations
59
Journal Articles
8
Other Scholarly Works
1
Book Chapter
The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps.
2020
V L Sutherland, D Gulezian, A Wilson, C Cerniglia, S Forry, C A McQueen, R Dietert, S Foley, H Young, S Khare, D Tweedie, A V Alekseyenko, D Mendrick, Chi-ming Chen, F Burns, Jose E Manautou, X Liang
Research Type: Journal Article

The Intersection of Toxicology and Metabolic Syndrome
2022
Jose E Manautou
Research Type: Poster/Presentation

The Role of Bromodomain and Extra-Terminal (BET) Proteins on APAP-Induced Hepatotoxicity
2020
Gregory Sartor, Raymond Xue, Ajay Chowdary Donepudi, Steven Toro, Mandakini Singh, Saren M Smith, Jose E Manautou
Research Type: Poster/Presentation

The Role of Drug Transporters on Hepatic Compensatory Tissue Proliferation and Non-Alcoholic Liver Disease
2019
Jose E Manautou
Research Type: Poster/Presentation

The Safety Aspects of Opioids Abuse; Potential Dangers to the Liver from Acetaminophen-containing Opioids
2017
Jose E Manautou
Research Type: Poster/Presentation

The Use of Genomic and Systems Biology Approaches to Identify Genetic Determinants of Susceptibility to Chemical-Induced Hepatotoxicity
2014
Jose E Manautou
Research Type: Poster/Presentation

The antitripanocide benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2).
2016
C I Ghanem, M L Ruiz, Jose E Manautou, J P Rigalli, N Ciriaci, M T Ronco, D E Francés, V A Catania, A M Bataille, V G Perdomo
Research Type: Journal Article

The beauty of toxicology: When a drug-induced liver injury project becomes a metabolic syndrome, adiposity and diabetes line of investigation
2023
Jose E Manautou
Research Type: Poster/Presentation

The growth of siRNA-based therapeutics: Updated clinical studies
2021
May Zhang, xiaobo zhong, Raman Bahal, Theodore Rasmussen, Jose E Manautou
Research Type: Journal Article

The modulation of transcriptional expression and inhibition of multidrug resistance associated protein 4 (MRP4) by analgesics and their primary metabolites
2020
Jose E Manautou, Carolina I. Ghanem, Renato J. Scialis
Research Type: Journal Article

The role of cyclic nucleotides in compensatory hepatocyte proliferation
2017
Li Wang, Jose E Manautou, Oladimeji Aladelokun
Research Type: Other Scholarly Work

The role of multi-drug resistance protein 4 (Mrp4, Abcc4) in protecting against acetaminophen (APAP)-induced hepatotoxicity
2012
Amy M Bataille, Jose E Manautou
Research Type: Poster/Presentation

Tolerance to Acetaminophen (APAP) Hepatotoxicity in a Mouse Model of Autoprotection Is Associated with Induction of Flavin-Containing Monooxygenase-3 (Fmo3)
2014
Igor Gurevich, Philip S Rohrer, Jose E Manautou, Theodore P. Rasmussen, Swetha A Rudraiah
Research Type: Poster/Presentation

Tolerance to Acetaminophen Hepatotoxicity in the mOuse Model of Acetaminophen Hepatoprotection is Associated with Induction of Flavin-Contaning Monooxygenase-3 (FMO3) in Hepatocytes
2013
Swetha Rudraiah, Theodore P Rasmussen, Igor Gurevich, Jose E Manautou
Research Type: Poster/Presentation

Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes.
2014
P R Rohrer, Igor Gurevich, Theodore Rasmussen, Jose E Manautou, S Rudraiah, R N Hines, M J Goedken
Research Type: Journal Article

Transcriptional Regulation of Brain ABC Transporters during Acute Acetaminophen (APAP) Intoxication in Mice and the Possible Role of the Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)
2014
Gahnem I Carolina, Jose E Manautou, Rudraiah S Swetha
Research Type: Poster/Presentation

Transcriptome Features of an HepaRG Cell Line Over-Expressing Human Flavin-Containing Monooxygenase-3 (FMO3)
2016
Jose E Manautou, xiaobo zhong, Swetha Rudraiah, Winfried H Krueger, Stephanie Peikos, Theodore Rasmussen
Research Type: Poster/Presentation

Transcriptomic Analysis of Liver from a Mouse Models Resistant to Acetaminophen Hepatotoxicity
2012
Jose E Manautou
Research Type: Poster/Presentation

Transgenic Expression of the Human MRP2 Transporter Reduces Cisplatin Accumulation and Nephrotoxicity in Mrp2-Null Mice.
2014
B Buckley, Jose E Manautou, S Syed, M J Goedken, X Wen, L M Aleksunes, E McCandlish, R Pelis
Research Type: Journal Article

Uncovering new functions of ABC transporter Multidrug resistance protein 4 (MRP4/ABCC4) beyond its well-documented in drug efflux: The link between MRP4 and metabolic syndrome”, Guangzhou, China, November 11, 2023.
2023
Jose E Manautou
Research Type: Poster/Presentation