Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Molecular mechanisms underlying chemical liver injury.
2012
Xinsheng Gu, Jose E Manautou
Research Type: Journal Article

Modulation of Hepatic MRP3/ABCC3 by Xenobiotics and Pathophysiological Conditions: Role in Drug Pharmacokinetics
2018
Carolina I Ghanem, Jose E Manautou
Research Type: Journal Article

Modification in the Expression of Brain ABC Transporters During Acute Acetaminophen Intoxication In Mice
2013
Gahnem I Carolina, Rudraiah S Swetha, Jose E Manautou
Research Type: Poster/Presentation

Mechanistic toxicity of FDA-approved ASO and siRNA drugs
2023
Jose E Manautou
Research Type: Poster/Presentation

Mechanistic Studies on the role of Liver Mrp4 (ABCC4) and Vanin-1 in Preventing Liver Injury by Acetaminophen” Denver, CA, May 10, 2012
2012
Jose E Manautou
Research Type: Poster/Presentation

Mechanistic Role(s) of Cytochrome(s) P450 in Oxidative Stress and Inflammation: New Opportunities for Drug Discovery
2013
Jose E Manautou, Bhagavatula Moorthy
Research Type: Poster/Presentation

Mechanistic Insights into the Development of Tolerance to Acetaminophen Hepatotoxicity
2012
Jose E Manautou
Research Type: Poster/Presentation

Loss of Mrp4 Function Disrupts Lipid Homeostasis and Impairs Liver Regeneration following Partial Hepatectomy
2017
Lee Ji-Young, Carvalho V Fabio, Katiria M Flores, Gregory J Smith, Jose E Manautou, Lee Yoojin
Research Type: Poster/Presentation

Liver Regeneration Following Partial Hepatectomy and the Influence of Drug Transporter Function on the Morphology of the Regained Tissue Mass
2021
Jose E Manautou
Research Type: Poster/Presentation

Let’s Talk About Sex: Is Nrf2 Responsible for Sex Differences in Susceptibility to Acetaminophen-Induced Hepatotoxicity in Mice?
2014
Jose E Manautou, Philip S. Rohrer
Research Type: Poster/Presentation

Leptin Mediated CD57 Expression on CD8+ve Cytotoxic T Cells Are Crucial for Toxicity-Induced Nonalcoholic Steatohepatitis
2014
Ratanesh K Seth, Anindya Chanda, Gregory Michelotti, Saurabh Chatterjee, Ashutosh Kumar, Maria B. Kadiiska, Anna D. Diehl, Suvarthi Das, Jose E Manautou
Research Type: Poster/Presentation

Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity
2019
Jose E Manautou, Michael J. Goedken, John D. Schuetz, Ajay Chowdary Donepudi
Research Type: Journal Article

Lack of Multidrug Resistance-associated Protein 4 Prolongs Partial Hepatectomy-induced Hepatic Steatosis
2020
Ji Young Lee, Marisa Pfohl, Steven J. Toro, Ajay Chowdary Donepudi, Jose E Manautou, Angela L. Slitt, Gregory J. Smith, John D. Schuetz, Oladimeji Aladelokun, Li Wang, Yoojin Lee
Research Type: Journal Article

Lack of Multidrug Resistance-Associated Protein 4 (Mrp4) Does Not Alter Susceptibility towards Acetaminophen Toxicity
2019
Jose E Manautou, Michael J Goedken, Ajay C Donepudi
Research Type: Poster/Presentation

La proteína asociada a resistencia a múltiples fármacos tipo 4 (ABCC4/MRP4), además de ser un modulador de la toxicidad de fármacos, es un factor determinante en el desarrollo de la enfermedad de hígado graso no alcohólico.
2023
Jose E Manautou
Research Type: Poster/Presentation

La proteina asociada a resistencia a multiples farmacos tipo 4 (ABCC4/MRP4) se perfila como un nuevo determinante genetico del la enfermedad de higado graso no alcoholico (NAFLD)
2023
Jose E Manautou
Research Type: Poster/Presentation

Knockdown of long noncoding RNAs hepatocyte nuclear factor 1a antisense RNA 1 and hepatocyte nuclear factor 4a antisense RNA 1 alters susceptibility of acetaminophen-induced cytotoxicity in HepaRG cells
2020
Jose E Manautou, Pei Wang, Xiao Bo Zhong, Liming Chen
Research Type: Journal Article

Knockdown of Long Noncoding RNAs Hepatocyte Nuclear Factor 1α Antisense RNA 1 and Hepatocyte Nuclear Factor 4α Antisense RNA 1 Alters Susceptibility of Acetaminophen-Induced Cytotoxicity in HepaRG Cells
2020
Liming Chen, Jose E Manautou, Xiao-bo Zhong, Pei Wang
Research Type: Journal Article

Is the Multidrug Resistance Protein MRP4 a New Player in the Development of Non-Alcoholic Liver Steatosis?", Amherst, MA, April 10, 2017.
2017
Jose E Manautou
Research Type: Poster/Presentation

Is nuclear factor erythroid 2-related factor 2 responsible for sex differences in susceptibility to acetaminophen-induced hepatotoxicity in mice?
2014
P R Rohrer, Jose E Manautou, S Rudraiah, M J Goedken
Research Type: Journal Article