Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Disruption of Multidrug Resistance Protein 4 (ABCC4) Functionality Raises the Risk of Hepatic Steatosis, Adiposity and Metabolic Syndrome
2022
Jose E Manautou
Research Type: Poster/Presentation

Differential expression and protein-protein interaction networks of the basic helix-loop-helix family of transcription factors in response to acetaminophen liver toxicity
2012
Jose E Manautou, Xinsheng Gu
Research Type: Poster/Presentation

Differential Regulation of Hepatic Flavin-Containing Monooxygenase-3 (FMO3) During Acetaminophen Toxicity in Mice
2012
Jose E Manautou, XInsheng Gu, Ronald N Hines, Swetha Rudraiah
Research Type: Poster/Presentation

Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice.
2014
S Rudraiah, S N Campion, L M Aleksunes, Jose E Manautou, J E Moscovitz, A L Slitt, A C Donepudi
Research Type: Journal Article

Differences in mRNA and Protein Expression of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) and Nrf2-Dependent Genes
2013
Jose E Manautou, Philip Rohrer
Research Type: Poster/Presentation

Development of precision medicine approaches based on inter-individual variability of BCRP/ABCG2
2019
xiaobo zhong, Jose E Manautou, Liming Chen, Theodore Rasmussen
Research Type: Journal Article

Conferencia de Cierre: Evidencia emergente de daño hepatico como secuela de COVID-19
2020
Jose E Manautou
Research Type: Poster/Presentation

Compensatory Induction of the Multidrug Resistance Associate Protein (Mrp4; ABCC4) in Response to Chemical Injury: Analysis of Regulatory Mechanisms” Langhorne, PA, November 8, 2011.
2011
Jose E Manautou
Research Type: Poster/Presentation

Closing Talk of the Society of Toxicology Undergraduate Educational Program: “Mentoring and Inspiring the Next Generation of Toxicologists: A commitment at a Global Scale”
2022
Jose E Manautou
Research Type: Poster/Presentation

Clinical and Mechanistic Aspects of Drug-Induced Hepatotoxicity Symposium: “Impact of Multidrug Resistance Protein 4 (MRP4/ABCC4) Function in Compensatory Cell Proliferation
2019
Jose E Manautou
Research Type: Poster/Presentation

Cholesterol-secreting and statin-responsive hepatocytes from human ES and iPS cells to model hepatic involvement in cardiovascular health.
2013
A Flamier, Jose E Manautou, V Barber, Winfried H Krueger, Theodore Rasmussen, B Tanasijevic, Xinsheng Gu
Research Type: Journal Article

Cholesterol-Secreting and Statin-Responsive Hepatocytes from Human ES and iPS Cells to Model Hepatic Involvement in Cardiovascular Health
2013
Borko Tanasijevic, Xinsheng Gu, Winfried H Krueger, Vanessa Barber, Theodore Rasmussen, Jose E Manautou, Anthony Flamier
Research Type: Journal Article

Characterization of Vanin-1 Knockout Mice Following Toxic Acetaminophen Exposure: Biotransformation Pathways, Immune Factors and Compensatory Hepatocellular Proliferation
2012
Jose E Manautou, Daniel W Ferreira, Philippe Naquet, Frack Galland
Research Type: Poster/Presentation

Casimersen for the treatment of Duchenne muscular dystrophy.
2022
Raman Bahal, S P Pradeep, Jose E Manautou, V Kasina, A P Laddha, S E Zakeri
Research Type: Journal Article

CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis.
2014
R K Seth, Jose E Manautou, G Michelotti, S Chatterjee, M B Kadiiska, A M Diehl, Sanjukta Das, A Kumar, A Chanda
Research Type: Journal Article

CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis
2014
S Chatterjee, A M Diehl, S Das, A Chanda, R K Seth, G Michelotti, J E Manautou
Research Type: Journal Article

Berry anthocyanins suppress the expression and secretin of pro-inflammatory mediators in macrophages by inhibiting nuclear translocation of NF-kB independent of NRF2-mediated mechanism
2014
Ji-Young Lee, Young-Ki Park, Jose E Manautou, Sanggil Lee, Yue Yang, Sung Koo, Tho X Pham, Ock Chun, Bohkyung Kim
Research Type: Journal Article

Astaxanthin prevents and reverses the activation of hepatic stellate cells via the modulation of histone deacetylase 9
2016
Young-Ki Park, Ji-Young Lee, Tho X Pham, Sung Koo, S Rudraiah, Jose E Manautou, Minkyung Bae, Yoojin Lee, Yue Yang
Research Type: Journal Article

Antioxidant fractions of Khaya grandifoliola C.DC. and Entada africana Guill. et Perr. induce nuclear translocation of Nrf2 in HC-04 cells.
2015
B Bradley, P Fewou Moundipa, J Njikam Manjia, R Fouemene Tsayem, S Rudraiah, F N Njayou, A M Amougou, Jose E Manautou
Research Type: Journal Article

Antioxidant Genes Respond Differentially to a Hepatotoxic Dose of Acetaminophen in Male and Female Mouse Brain Barriers
2017
James L Renfro, Katiria M Flores, Jose E Manautou
Research Type: Poster/Presentation