Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Scholarly Contributions

186 Scholarly Contributions

118
Poster/Presentations
59
Journal Articles
8
Other Scholarly Works
1
Book Chapter
Analysis of acetaminophen-induced hepatotoxicity in female c57BL/6J mice lacking the ATP-binding cassette subfamily C member 4 (Abcc4, Mrp4)
2015
Emily Daniel, Amy M Bataille, Jose E Manautou
Research Type: Poster/Presentation

Analysis of Changes in Hepatic Gene Expression in a Murine Model of Tolerance to Acetaminophen Hepatotoxicity (Autoprotection)
2014
Ahmed E Enayetallah, Xinsheng Gu, Jose E Manautou, Lauren M Aleksunes, Meeghan A O’Connor, Michael P Lawton, Petra Koza-Taylor, Sarah N Campion
Research Type: Journal Article

Analysis of Changes in Hepatic Gene Expression in a Murine Model of Resistance to Acetaminophen Hepatotoxicity
2013
Jose E Manautou
Research Type: Poster/Presentation

Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.
2015
R P Erickson, Jose E Manautou, R N Hardwick, S A Xanthakos, S N Campion, D W Ferreira, A M Bataille, M D Merrell, N J Cherrington, M J Canet, H Hesham A-Kader
Research Type: Journal Article

Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease
2013
N J Cherrington, A L Slitt, R N Hardwick, A D Lake, Jose E Manautou, V R More, D W Ferreira
Research Type: Journal Article

Altered Transcription Initiation and Exonization of the First Intron of the Human Liver ABCC4 Gene in Tissue Specimens from Cases of Acetaminophen Overdose
2014
Jose E Manautou, Xinsheng Gu
Research Type: Poster/Presentation

Alterations of cytochrome P450-mediated drug metabolism during liver repair and regeneration after acetaminophen-induced liver injury in mice
2022
Yifan Bao, Xiaochao Ma, Jose E Manautou, Mi Phan, Junjie Zhu, xiaobo zhong
Research Type: Journal Article

Adverse Drug Reactions and Toxicity of the Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
2022
Kristy Zhang, Hangyu Wu, Rajvi Parikh, xiaobo zhong, Theodore Rasmussen, Feryal Alhamadani, Jose E Manautou, Raman Bahal
Research Type: Journal Article

Acute glutathione depletion induces hepatic methylglyoxal accumulation by impairing its detoxification to D-lactate
2013
Eunice Ma, Young-Ki Park, Jose E Manautou, Ji-Young Lee, Christopher Masterjohn, Richard S Bruno, Ruisong Pei
Research Type: Journal Article

Acute acetaminophen intoxication induces direct neurotoxicity in rats manifested as astrogliosis and decreased dopaminergic markers in brain areas associated with locomotor regulation
2019
Fernanda De Fino, Sonia A. Martínez, Carolina I. Ghanem, Jose E Manautou, María Belén Vigo, Veronica Bisagno, Gimena Gómez, María Julia Pérez, Alejandra Scazziota, María Beatriz Di Carlo
Research Type: Journal Article

Acute Acetaminophen (APAP) Intoxication Decreases Locomotor Activity and Modifies Glial Cells Markers in Brain Areas Involved in the Locomotion and Memory Regulation
2016
S Martinez, Jose E Manautou, M B Di Carlo, Carolina I Ghanem, M B Vigo, A Scazziota, E Casim, M J Perez
Research Type: Poster/Presentation

Acetaminophen-induced liver injury alters expression and activities of cytochrome P450 enzymes in an age-dependent manner in mouse liver
2020
Lirong Zhang, Jose E Manautou, Junjie Zhu, Xiao Bo Zhong, Jian Shi, Xiaochao Ma, Pei Wang, Xueyan Shao, Yifan Bao, Jingcheng Xiao, Hao Jie Zhu
Research Type: Journal Article

Acetaminophen-Induced Liver Injury Alters Expression and Activitiesof Cytochrome P450 Enzymes in an Age-Dependent Manner in Mouse Liver
2020
Jingcheng Xiao, Pei Wang, Lirong Zhang, Jose E Manautou, Jian Shi, Junjie Zhu, Xiaochao Ma, Yifan Bao, Hao-jie Zhu, Xiao-bo Zhong, Xueyan Shao
Research Type: Journal Article

Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity.
2016
Jose E Manautou, C I Ghanem, M J Pérez, A D Mottino
Research Type: Journal Article

Acetaminophen at low doses depletes airway glutathione and alters respiratory reflex responses
2013
John B Morris, Joseph A Cichicki, Jose E Manautou, Gregory J Smith
Research Type: Poster/Presentation

Acetaminophen Regulates the Expression of ABCC Multidrug Resistance Proteins as a Compensatory Response to Tissue Injury
2012
Jose E Manautou
Research Type: Poster/Presentation

Acetaminophen Produces Oxidative Stress in the Airways and Modulates Respiratory Responses to Oxidant Challenge
2013
Joseph A Cichocki, Jose E Manautou, John B Morris, Gregory J Smith
Research Type: Poster/Presentation

Acetaminophen Attenuates House Dust Mite-Induced Allergic Airway Disease in Mice.
2016
G J Smith, R S Thrall, Jose E Manautou, John B Morris, M M Cloutier
Research Type: Journal Article

Acetaminophen Attenuates House Dust Mite Induced Allergic Airway Disease in Mice
2016
Roger S. Thrall, John B Morris, Michelle M Cloutier, Gregory J Smith, Jose E Manautou
Research Type: Poster/Presentation

Academic Leader, Mentor and Researcher in Drug-Induced Hepatotoxicity: Maintaining a Balance for Success
2019
Jose E Manautou
Research Type: Poster/Presentation