Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Green tea extract attenuated hepatic steatosis by decreasing adipose lipogenesis and enhancing hepatic antioxidant defenses in ob/ob mice
2011
Minyu Chung, M O'Connor, Hea Jin Park, Sung Koo, D A DiNatale, Jose E Manautou, Ji-Young Lee, Richard S Bruno, Young-Ki Park
Research Type: Journal Article

Induction of Hepatic Vanin-1 Gene Expression as a Protective Measure Against Acetaminophen Hepatotoxicity",
2011
Jose E Manautou
Research Type: Poster/Presentation

Inhibition of Bile Salt Efflux Protein and Involvement of Hepatic Transporters in Drug-Induced Hepatotoxicity”, June 8, 2011, Philadelphia, PA
2011
Jose E Manautou
Research Type: Poster/Presentation

Compensatory Induction of the Multidrug Resistance Associate Protein (Mrp4; ABCC4) in Response to Chemical Injury: Analysis of Regulatory Mechanisms” Langhorne, PA, November 8, 2011.
2011
Jose E Manautou
Research Type: Poster/Presentation

Hepatoprotective Effect of Peroxisome Proliferators is Associated with Induction of Vanin-1 Gene Expression
2011
Jose E Manautou
Research Type: Poster/Presentation

Role of Vanin-1 in Acetaminophen Hepatotoxicity
2011
Jose E Manautou
Research Type: Poster/Presentation

Molecular mechanisms underlying chemical liver injury.
2012
Xinsheng Gu, Jose E Manautou
Research Type: Journal Article

The role of multi-drug resistance protein 4 (Mrp4, Abcc4) in protecting against acetaminophen (APAP)-induced hepatotoxicity
2012
Amy M Bataille, Jose E Manautou
Research Type: Poster/Presentation

Mechanistic Studies on the role of Liver Mrp4 (ABCC4) and Vanin-1 in Preventing Liver Injury by Acetaminophen” Denver, CA, May 10, 2012
2012
Jose E Manautou
Research Type: Poster/Presentation

Inhibition of Drug Transporter Function as a Determinant of Drug-Induced Hepatotoxicity
2012
Jose E Manautou
Research Type: Poster/Presentation

Multiplicity of 5'-end of human hepatic multidrug resistance-associated protein 4 transcripts
2012
Vincent Ramirez, Xinsheng Gu, Jose E Manautou, Brian J Aneskievich
Research Type: Poster/Presentation

Primary cultures of mouse renal proximal tubule epithelial cells as a model for studying acetaminophen (APAP)-induced nephrotoxicity
2012
James L Renfro, Amy M. Bataille, Jose E Manautou
Research Type: Poster/Presentation

Transcriptomic Analysis of Liver from a Mouse Models Resistant to Acetaminophen Hepatotoxicity
2012
Jose E Manautou
Research Type: Poster/Presentation

Acetaminophen Regulates the Expression of ABCC Multidrug Resistance Proteins as a Compensatory Response to Tissue Injury
2012
Jose E Manautou
Research Type: Poster/Presentation

Vanin-1 Gene Expression: Determinant of Acetaminophen Hepatotoxicity J. Manautou1, D.W. Ferreira1, P. Naquet2, F. Galland2
2012
Philippe Naquet, Franck Galland, Daniel W Ferreira, Jose E Manautou
Research Type: Poster/Presentation

Differential Regulation of Hepatic Flavin-Containing Monooxygenase-3 (FMO3) During Acetaminophen Toxicity in Mice
2012
Jose E Manautou, XInsheng Gu, Ronald N Hines, Swetha Rudraiah
Research Type: Poster/Presentation

Differential expression and protein-protein interaction networks of the basic helix-loop-helix family of transcription factors in response to acetaminophen liver toxicity
2012
Jose E Manautou, Xinsheng Gu
Research Type: Poster/Presentation

Mechanistic Insights into the Development of Tolerance to Acetaminophen Hepatotoxicity
2012
Jose E Manautou
Research Type: Poster/Presentation

Protection against acetaminophen cytotoxicity by PPAR and RXR agonists: Determining the role of changes in Vanin-1 mRNA expression
2012
Jose E Manautou
Research Type: Poster/Presentation

Evaluation of hepatic flavin-containing monooxygenase 3 (Fmo3) gene regulation, protein expression, and functional activity in response to acetaminophen toxicity
2012
Swetha Rudraiah, Jose E Manautou
Research Type: Poster/Presentation