Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Characterization of Vanin-1 Knockout Mice Following Toxic Acetaminophen Exposure: Biotransformation Pathways, Immune Factors and Compensatory Hepatocellular Proliferation
2012
Jose E Manautou, Daniel W Ferreira, Philippe Naquet, Frack Galland
Research Type: Poster/Presentation

Rubescins A, B and C: Havanensin Type Limonoïds from Root Bark of Trichilia rubescens that Protect HC-04 Cells against Oxidative Stress Induced by Hydrogen Peroxide
2013
Jose E Manautou, Kirk Marat, Njayou F Nico, Mkounga Pierre, Nkengfack Ephram, Armelle T Tsamo, Philip Hultin
Research Type: Journal Article

Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease
2013
N J Cherrington, A L Slitt, R N Hardwick, A D Lake, Jose E Manautou, V R More, D W Ferreira
Research Type: Journal Article

Cholesterol-secreting and statin-responsive hepatocytes from human ES and iPS cells to model hepatic involvement in cardiovascular health.
2013
A Flamier, Jose E Manautou, V Barber, Winfried H Krueger, Theodore Rasmussen, B Tanasijevic, Xinsheng Gu
Research Type: Journal Article

Cholesterol-Secreting and Statin-Responsive Hepatocytes from Human ES and iPS Cells to Model Hepatic Involvement in Cardiovascular Health
2013
Borko Tanasijevic, Xinsheng Gu, Winfried H Krueger, Vanessa Barber, Theodore Rasmussen, Jose E Manautou, Anthony Flamier
Research Type: Journal Article

Nrf2: A Potential Target for New Therapeutics in Liver Disease
2013
Jose E Manautou, Amy A Bataille
Research Type: Journal Article

Rubescins A, B and C: new havanensin type limonoids from root bark of Trichilia rubescens (Meliaceae).
2013
P Mkounga, A Tsamo Tontsa, P G Hultin, Jose E Manautou, F N Njayou, M Kirk, A E Nkengfack
Research Type: Journal Article

Acute glutathione depletion induces hepatic methylglyoxal accumulation by impairing its detoxification to D-lactate
2013
Eunice Ma, Young-Ki Park, Jose E Manautou, Ji-Young Lee, Christopher Masterjohn, Richard S Bruno, Ruisong Pei
Research Type: Journal Article

Tolerance to Acetaminophen Hepatotoxicity in the mOuse Model of Acetaminophen Hepatoprotection is Associated with Induction of Flavin-Contaning Monooxygenase-3 (FMO3) in Hepatocytes
2013
Swetha Rudraiah, Theodore P Rasmussen, Igor Gurevich, Jose E Manautou
Research Type: Poster/Presentation

Differences in mRNA and Protein Expression of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) and Nrf2-Dependent Genes
2013
Jose E Manautou, Philip Rohrer
Research Type: Poster/Presentation

Analysis of Changes in Hepatic Gene Expression in a Murine Model of Resistance to Acetaminophen Hepatotoxicity
2013
Jose E Manautou
Research Type: Poster/Presentation

Genomic Identification of Novel Pathways that Confer Resistance to Chemical Induced-Liver Injury: Validation Using Cellular and Transgenic Models
2013
Jose E Manautou
Research Type: Poster/Presentation

Acetaminophen Produces Oxidative Stress in the Airways and Modulates Respiratory Responses to Oxidant Challenge
2013
Joseph A Cichocki, Jose E Manautou, John B Morris, Gregory J Smith
Research Type: Poster/Presentation

Role of Vanin-1 in acetaminophen hepatotoxicity: Regulation of thiol homeostasis and immune response to liver injury
2013
Jose E Manautou
Research Type: Poster/Presentation

Vanin-1 Knockout Mice Exhibit Alterations in Compensatory Immune Infiltration and Hepatocyte Proliferation following Acetaminophen Toxicity
2013
Philippe Naquet, Daniel W Ferreira, Franck Gallard, Jose E Manautou
Research Type: Poster/Presentation

Hepatic Transporters and Development on Tolerance to Hepatotoxicity by Acetaminophen
2013
Jose E Manautou
Research Type: Poster/Presentation

Hepatic Flavin-Containing Monooxygenase-3 (FMO3) Protein Is Inducible by Acetaminophen Treatment
2013
Jose E Manautou, Swetha A Rudraiah
Research Type: Poster/Presentation

Mechanistic Role(s) of Cytochrome(s) P450 in Oxidative Stress and Inflammation: New Opportunities for Drug Discovery
2013
Jose E Manautou, Bhagavatula Moorthy
Research Type: Poster/Presentation

Acetaminophen at low doses depletes airway glutathione and alters respiratory reflex responses
2013
John B Morris, Joseph A Cichicki, Jose E Manautou, Gregory J Smith
Research Type: Poster/Presentation

The ABC’s of Acetaminophen Toxicity
2013
Jose E Manautou
Research Type: Poster/Presentation