Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Scholarly Contributions

186 Scholarly Contributions

118
Poster/Presentations
59
Journal Articles
8
Other Scholarly Works
1
Book Chapter
Suppressive Effect of HES1 (Drosophila Hairy and Enhancer of Split-1) on Human Hepatic Multidrug Resistance-Associated Protein 4 (MRP4) Gene Expression and Induction of HES1 by Oxidative Stress
2013
Xinsheng Gu, Jose E Manautou
Research Type: Poster/Presentation

Role of Vanin-1 in acetaminophen hepatotoxicity: regulation of thiol homeostasis and immune response to liver injury
2013
Jose E Manautou
Research Type: Poster/Presentation

Proteina de Resistencia a Multidrogas 4 (MRP4, ABCC4) Como un Factor Potencial de Resistencia a la Toxicidad Provocada por Acetaminofeno
2013
Jose E Manautou
Research Type: Poster/Presentation

Modification in the Expression of Brain ABC Transporters During Acute Acetaminophen Intoxication In Mice
2013
Gahnem I Carolina, Rudraiah S Swetha, Jose E Manautou
Research Type: Poster/Presentation

Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice.
2014
S Rudraiah, S N Campion, L M Aleksunes, Jose E Manautou, J E Moscovitz, A L Slitt, A C Donepudi
Research Type: Journal Article

Is nuclear factor erythroid 2-related factor 2 responsible for sex differences in susceptibility to acetaminophen-induced hepatotoxicity in mice?
2014
P R Rohrer, Jose E Manautou, S Rudraiah, M J Goedken
Research Type: Journal Article

CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis.
2014
R K Seth, Jose E Manautou, G Michelotti, S Chatterjee, M B Kadiiska, A M Diehl, Sanjukta Das, A Kumar, A Chanda
Research Type: Journal Article

Analysis of Changes in Hepatic Gene Expression in a Murine Model of Tolerance to Acetaminophen Hepatotoxicity (Autoprotection)
2014
Ahmed E Enayetallah, Xinsheng Gu, Jose E Manautou, Lauren M Aleksunes, Meeghan A O’Connor, Michael P Lawton, Petra Koza-Taylor, Sarah N Campion
Research Type: Journal Article

CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis
2014
S Chatterjee, A M Diehl, S Das, A Chanda, R K Seth, G Michelotti, J E Manautou
Research Type: Journal Article

Berry anthocyanins suppress the expression and secretin of pro-inflammatory mediators in macrophages by inhibiting nuclear translocation of NF-kB independent of NRF2-mediated mechanism
2014
Ji-Young Lee, Young-Ki Park, Jose E Manautou, Sanggil Lee, Yue Yang, Sung Koo, Tho X Pham, Ock Chun, Bohkyung Kim
Research Type: Journal Article

Transgenic Expression of the Human MRP2 Transporter Reduces Cisplatin Accumulation and Nephrotoxicity in Mrp2-Null Mice.
2014
B Buckley, Jose E Manautou, S Syed, M J Goedken, X Wen, L M Aleksunes, E McCandlish, R Pelis
Research Type: Journal Article

Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes.
2014
P R Rohrer, Igor Gurevich, Theodore Rasmussen, Jose E Manautou, S Rudraiah, R N Hines, M J Goedken
Research Type: Journal Article

Tolerance to Acetaminophen (APAP) Hepatotoxicity in a Mouse Model of Autoprotection Is Associated with Induction of Flavin-Containing Monooxygenase-3 (Fmo3)
2014
Igor Gurevich, Philip S Rohrer, Jose E Manautou, Theodore P. Rasmussen, Swetha A Rudraiah
Research Type: Poster/Presentation

Let’s Talk About Sex: Is Nrf2 Responsible for Sex Differences in Susceptibility to Acetaminophen-Induced Hepatotoxicity in Mice?
2014
Jose E Manautou, Philip S. Rohrer
Research Type: Poster/Presentation

The Use of Genomic and Systems Biology Approaches to Identify Genetic Determinants of Susceptibility to Chemical-Induced Hepatotoxicity
2014
Jose E Manautou
Research Type: Poster/Presentation

New Approaches to Identify Adaptive/Adverse Responses: Liver As a Model System
2014
Jose E Manautou
Research Type: Poster/Presentation

Leptin Mediated CD57 Expression on CD8+ve Cytotoxic T Cells Are Crucial for Toxicity-Induced Nonalcoholic Steatohepatitis
2014
Ratanesh K Seth, Anindya Chanda, Gregory Michelotti, Saurabh Chatterjee, Ashutosh Kumar, Maria B. Kadiiska, Anna D. Diehl, Suvarthi Das, Jose E Manautou
Research Type: Poster/Presentation

Altered Transcription Initiation and Exonization of the First Intron of the Human Liver ABCC4 Gene in Tissue Specimens from Cases of Acetaminophen Overdose
2014
Jose E Manautou, Xinsheng Gu
Research Type: Poster/Presentation

Utilization of System Genomics in the Identification of Genetic Determinants of Adaptation to Chemical Liver Injury
2014
Jose E Manautou
Research Type: Poster/Presentation

Flavin-containing Monooxygenase-3 and Vanin-1: Two Novel Genetic Determinants of Acetaminophen Hepatotoxicity
2014
Jose E Manautou
Research Type: Poster/Presentation