Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Scholarly Contributions

186 Scholarly Contributions

118
Poster/Presentations
59
Journal Articles
8
Other Scholarly Works
1
Book Chapter
Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet.
2016
T N Sapper, Richard Bruno, M V Moller, K E Schill, J Li, Jose E Manautou, P R Rohrer, C Chitchumroonchokchai, S Rudraiah, E Mah, J D McDonald
Research Type: Journal Article

Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells.
2016
S Rudraiah, R N Hines, Xinsheng Gu, Jose E Manautou
Research Type: Journal Article

Post-Transcriptional Regulation of the ABC Transporters Mrp2, Bcrp and P-gp in Enterocytes During Acute Acetaminophen (APAP) Intoxication in Mice
2016
Jose E Manautou, Aldo D Mottino, L Obrea, Carolina I Ghanem, Swetha Rudraiah
Research Type: Poster/Presentation

Acetaminophen Attenuates House Dust Mite Induced Allergic Airway Disease in Mice
2016
Roger S. Thrall, John B Morris, Michelle M Cloutier, Gregory J Smith, Jose E Manautou
Research Type: Poster/Presentation

Potential Roles of Diclofenac Acyl Glucuronide in the Pathomechanism of Intestinal Toxicity After High Dose Diclofenac
2016
Ivan L Csanaky, Renato J Scialis, Jose E Manautou
Research Type: Poster/Presentation

Drug Induced Liver Injury – How Mechanistic Insights Aid Preclinical Detection and Prediction
2016
Jose E Manautou
Research Type: Poster/Presentation

Transcriptome Features of an HepaRG Cell Line Over-Expressing Human Flavin-Containing Monooxygenase-3 (FMO3)
2016
Jose E Manautou, xiaobo zhong, Swetha Rudraiah, Winfried H Krueger, Stephanie Peikos, Theodore Rasmussen
Research Type: Poster/Presentation

Acute Acetaminophen (APAP) Intoxication Decreases Locomotor Activity and Modifies Glial Cells Markers in Brain Areas Involved in the Locomotion and Memory Regulation
2016
S Martinez, Jose E Manautou, M B Di Carlo, Carolina I Ghanem, M B Vigo, A Scazziota, E Casim, M J Perez
Research Type: Poster/Presentation

Histone deacetylase 9 plays a role in the anti-fibrogenic effect of astaxanthin in hepatic stellate cells
2017
Yue Yang, Ji-Young Lee, Tho X Pham, Yoojin Lee, Young-Ki Park, Jose E Manautou, Minkyung Bae, Ellen Harness, S Rudraiah, Sung Koo
Research Type: Journal Article

Gender-specific expression of ATP-binding cassette (Abc) transporters and cytoprotective genes in mouse choroid plexus.
2017
Jose E Manautou, K Flores, James L Renfro
Research Type: Journal Article

The role of cyclic nucleotides in compensatory hepatocyte proliferation
2017
Li Wang, Jose E Manautou, Oladimeji Aladelokun
Research Type: Other Scholarly Work

Is the Multidrug Resistance Protein MRP4 a New Player in the Development of Non-Alcoholic Liver Steatosis?", Amherst, MA, April 10, 2017.
2017
Jose E Manautou
Research Type: Poster/Presentation

Importance of Liver Transporters in Hepatotoxicity Induced by Chemicals
2017
Jose E Manautou
Research Type: Poster/Presentation

Novel Genetic Determinants of Acetaminophen Toxicity and the Potential for Validation as Biomarkers
2017
Jose E Manautou
Research Type: Poster/Presentation

Loss of Mrp4 Function Disrupts Lipid Homeostasis and Impairs Liver Regeneration following Partial Hepatectomy
2017
Lee Ji-Young, Carvalho V Fabio, Katiria M Flores, Gregory J Smith, Jose E Manautou, Lee Yoojin
Research Type: Poster/Presentation

The Safety Aspects of Opioids Abuse; Potential Dangers to the Liver from Acetaminophen-containing Opioids
2017
Jose E Manautou
Research Type: Poster/Presentation

What Determines the Development of Tolerance to Acetaminophen Hepatotoxicity
2017
Jose E Manautou
Research Type: Poster/Presentation

Nrf2 Influences the Regulation of PPAR-Dependent Genes in Mouse Liver
2017
Katiria M Flores, Carvalho V Fabio, Gregory J Smith, Jose E Manautou
Research Type: Poster/Presentation

Antioxidant Genes Respond Differentially to a Hepatotoxic Dose of Acetaminophen in Male and Female Mouse Brain Barriers
2017
James L Renfro, Katiria M Flores, Jose E Manautou
Research Type: Poster/Presentation

ABC Transporters in Drug-Induced Liver Injury
2017
Jose E Manautou
Research Type: Poster/Presentation