Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Casimersen for the treatment of Duchenne muscular dystrophy.
2022
Raman Bahal, S P Pradeep, Jose E Manautou, V Kasina, A P Laddha, S E Zakeri
Research Type: Journal Article

Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
2022
Sunna Liu, xiaobo zhong, Sreenidhi Nair, Theodore Rasmussen, Anna Liu, Anagha Gogate, Raman Bahal, Julia M Migliorati, Jose E Manautou
Research Type: Journal Article

Alterations of cytochrome P450-mediated drug metabolism during liver repair and regeneration after acetaminophen-induced liver injury in mice
2022
Yifan Bao, Xiaochao Ma, Jose E Manautou, Mi Phan, Junjie Zhu, xiaobo zhong
Research Type: Journal Article

Editorial overview: New cause for concern–Emerging nephrotoxicants and mechanisms of renal injury
2022
José E. Manautou, Lauren M. Aleksunes, Gary O. Rankin
Research Type: Other Scholarly Work

Nedosiran, a Candidate siRNA Drug for the Treatment of Primary Hyperoxaluria: Design, Development, and Clinical Studies
2022
Theodore Rasmussen, Jenny Zhao, Julia M. Migliorati, Raman Bahal, Jose E Manautou, Milan Shah, Anna Liu, Sherouk M. Tawfik, Xiao Bo Zhong
Research Type: Other Scholarly Work

Rethinking Subthreshold Effects in Regulatory Chemical Risk Assessments
2022
Takayoshi Koike, Olga Ioanna Kalantzi, Stephen O. Duke, Manish Kumar, Alessandra De Marco, Vasileios Fotopoulos, Aristidis Tsatsakis, Yolanda Picó, Pierre Sicard, Ivo Iavicoli, José E. Manautou, Raul Narciso Guedes, Elena Paoletti, A. Wallace Hayes, Wenjie Wang, Michael N. Moore, Despo Fatta-Kassinos, Ricardo Antunes Azevedo, G. Christopher Cutler, Anca Oana Docea, Josep Peñuelas, Alexander I. Vardavas, David Costantini, Teresa Rocha-Santos, Edward J. Calabrese, Christian Sonne, Jörg Rinklebe, Ramin Rezaee, Demetrios Kouretas, Michael Aschner, Evgenios Agathokleous, Christopher Teaf, Prosun Bhattacharya, José G. Dórea, Russel J. Reiter, Dami√† Barceló, Thomas Efferth, Antonio Ginebreda, Eddy Y. Zeng
Research Type: Other Scholarly Work

Role and Regulation of Hepatobiliary ATP-Binding Cassette Transporters during Chemical-Induced Liver Injury
2022
Carolina I. Ghanem, Jose E Manautou
Research Type: Other Scholarly Work

Potential deleterious effects of paracetamol dose regime used in Nigeria versus that of the United States of America
2022
Jose E Manautou, Cecilia Nwadiuto Amadi, Ifeyinwa Chijioke-Nwauche, Orish E. Orisakwe, Samuel James Offor
Research Type: Other Scholarly Work

Safety evaluation of chemicals and drugs regarding their liver toxicity
2022
Jose E Manautou
Research Type: Poster/Presentation

Risk Assessment of Drug-Induced Liver Toxicity
2022
Jose E Manautou
Research Type: Poster/Presentation

Closing Talk of the Society of Toxicology Undergraduate Educational Program: “Mentoring and Inspiring the Next Generation of Toxicologists: A commitment at a Global Scale”
2022
Jose E Manautou
Research Type: Poster/Presentation

The Intersection of Toxicology and Metabolic Syndrome
2022
Jose E Manautou
Research Type: Poster/Presentation

Hepatic Multidrug Resistance Protein 4 (Mrp4): Its Journey through Drug-Induced Liver Injury, Compensatory Hepatocellular Proliferation, Hepatic Steatosis and Metabolic Syndrome
2022
Jose E Manautou
Research Type: Poster/Presentation

Multidrug Resistance Protein-4 (Mrp4): A New Member in the Constellation of Factors Contributing to Non-alcoholic Fatty Liver Disease and Metabolic Syndrome
2022
Jose E Manautou
Research Type: Poster/Presentation

Disruption of Multidrug Resistance Protein 4 (ABCC4) Functionality Raises the Risk of Hepatic Steatosis, Adiposity and Metabolic Syndrome
2022
Jose E Manautou
Research Type: Poster/Presentation

A holistic analysis of the intrinsic and delivery-mediated toxicity of siRNA therapeutics.
2023
Jose E Manautou, xiaobo zhong, Xiuling Lu, Sheyda Ranjbar
Research Type: Journal Article

Multivalent Lactobionic Acid and N-Acetylgalactosamine-Conjugated Peptide Nucleic Acids for Efficient In Vivo Targeting of Hepatocytes
2023
Anisha Gupta, José E. Manautou, Vikas Kumar, Aniket Wahane, Raman Bahal
Research Type: Journal Article

Multidrug Resistance Protein-4 (Mrp4) at the Intersection of the Liver-Adipose Tissue Axis”, Belgrade, Serbia, May 30, 2023 (plenary talk)
2023
Jose E Manautou
Research Type: Poster/Presentation

La proteina asociada a resistencia a multiples farmacos tipo 4 (ABCC4/MRP4) se perfila como un nuevo determinante genetico del la enfermedad de higado graso no alcoholico (NAFLD)
2023
Jose E Manautou
Research Type: Poster/Presentation

The beauty of toxicology: When a drug-induced liver injury project becomes a metabolic syndrome, adiposity and diabetes line of investigation
2023
Jose E Manautou
Research Type: Poster/Presentation