Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Scholarly Contributions

186 Scholarly Contributions

118
Poster/Presentations
59
Journal Articles
8
Other Scholarly Works
1
Book Chapter
Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses.
2016
D W Ferreira, F Galland, P Naquet, L Chasson, M J Goedken, S Rommelaere, Jose E Manautou
Research Type: Journal Article

From hepatoprotection models to new therapeutic modalities for treating liver diseases: a personal perspective.
2016
S Rudraiah, Jose E Manautou
Research Type: Journal Article

Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity.
2016
Jose E Manautou, C I Ghanem, M J Pérez, A D Mottino
Research Type: Journal Article

Acetaminophen Attenuates House Dust Mite-Induced Allergic Airway Disease in Mice.
2016
G J Smith, R S Thrall, Jose E Manautou, John B Morris, M M Cloutier
Research Type: Journal Article

Astaxanthin prevents and reverses the activation of hepatic stellate cells via the modulation of histone deacetylase 9
2016
Young-Ki Park, Ji-Young Lee, Tho X Pham, Sung Koo, S Rudraiah, Jose E Manautou, Minkyung Bae, Yoojin Lee, Yue Yang
Research Type: Journal Article

The antitripanocide benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2).
2016
C I Ghanem, M L Ruiz, Jose E Manautou, J P Rigalli, N Ciriaci, M T Ronco, D E Francés, V A Catania, A M Bataille, V G Perdomo
Research Type: Journal Article

Elucidation of the Mechanisms through Which the Reactive Metabolite Diclofenac Acyl Glucuronide Can Mediate Toxicity.
2016
R J Scialis, Jose E Manautou
Research Type: Journal Article

Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet.
2016
T N Sapper, Richard Bruno, M V Moller, K E Schill, J Li, Jose E Manautou, P R Rohrer, C Chitchumroonchokchai, S Rudraiah, E Mah, J D McDonald
Research Type: Journal Article

Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells.
2016
S Rudraiah, R N Hines, Xinsheng Gu, Jose E Manautou
Research Type: Journal Article

Post-Transcriptional Regulation of the ABC Transporters Mrp2, Bcrp and P-gp in Enterocytes During Acute Acetaminophen (APAP) Intoxication in Mice
2016
Jose E Manautou, Aldo D Mottino, L Obrea, Carolina I Ghanem, Swetha Rudraiah
Research Type: Poster/Presentation

Acetaminophen Attenuates House Dust Mite Induced Allergic Airway Disease in Mice
2016
Roger S. Thrall, John B Morris, Michelle M Cloutier, Gregory J Smith, Jose E Manautou
Research Type: Poster/Presentation

Potential Roles of Diclofenac Acyl Glucuronide in the Pathomechanism of Intestinal Toxicity After High Dose Diclofenac
2016
Ivan L Csanaky, Renato J Scialis, Jose E Manautou
Research Type: Poster/Presentation

Drug Induced Liver Injury – How Mechanistic Insights Aid Preclinical Detection and Prediction
2016
Jose E Manautou
Research Type: Poster/Presentation

Transcriptome Features of an HepaRG Cell Line Over-Expressing Human Flavin-Containing Monooxygenase-3 (FMO3)
2016
Jose E Manautou, xiaobo zhong, Swetha Rudraiah, Winfried H Krueger, Stephanie Peikos, Theodore Rasmussen
Research Type: Poster/Presentation

Acute Acetaminophen (APAP) Intoxication Decreases Locomotor Activity and Modifies Glial Cells Markers in Brain Areas Involved in the Locomotion and Memory Regulation
2016
S Martinez, Jose E Manautou, M B Di Carlo, Carolina I Ghanem, M B Vigo, A Scazziota, E Casim, M J Perez
Research Type: Poster/Presentation

Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.
2015
R P Erickson, Jose E Manautou, R N Hardwick, S A Xanthakos, S N Campion, D W Ferreira, A M Bataille, M D Merrell, N J Cherrington, M J Canet, H Hesham A-Kader
Research Type: Journal Article

Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice.
2015
Jose E Manautou, M J Goedken, S Rudraiah, M B Vigo, C I Ghanem, A M Bataille
Research Type: Journal Article

Antioxidant fractions of Khaya grandifoliola C.DC. and Entada africana Guill. et Perr. induce nuclear translocation of Nrf2 in HC-04 cells.
2015
B Bradley, P Fewou Moundipa, J Njikam Manjia, R Fouemene Tsayem, S Rudraiah, F N Njayou, A M Amougou, Jose E Manautou
Research Type: Journal Article

Influence of Vanin-1 and Catalytic Products in Liver During Normal and Oxidative Stress Conditions.
2015
Jose E Manautou, D W Ferreira, P Naquet
Research Type: Journal Article

Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac.
2015
Jose E Manautou, M J Goedken, R J Scialis, I L Csanaky
Research Type: Journal Article