Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Scholarly Contributions

186 Scholarly Contributions

118
Poster/Presentations
59
Journal Articles
8
Other Scholarly Works
1
Book Chapter
A holistic analysis of the intrinsic and delivery-mediated toxicity of siRNA therapeutics.
2023
Jose E Manautou, xiaobo zhong, Xiuling Lu, Sheyda Ranjbar
Research Type: Journal Article

Multivalent Lactobionic Acid and N-Acetylgalactosamine-Conjugated Peptide Nucleic Acids for Efficient In Vivo Targeting of Hepatocytes
2023
Anisha Gupta, José E. Manautou, Vikas Kumar, Aniket Wahane, Raman Bahal
Research Type: Journal Article

Nephrotoxicity of marketed antisense oligonucleotide drugs
2022
Feryal Alhamadani, Rajvi Parikh, Theodore Rasmussen, Evan M McCabe, SooWan Lee, Xiaobo Zhong, Jose E Manautou, Aniket Wahane, Hangyu Wu, Raman Bahal, Kristy Zhang
Research Type: Journal Article

Adverse Drug Reactions and Toxicity of the Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
2022
Kristy Zhang, Hangyu Wu, Rajvi Parikh, xiaobo zhong, Theodore Rasmussen, Feryal Alhamadani, Jose E Manautou, Raman Bahal
Research Type: Journal Article

Casimersen for the treatment of Duchenne muscular dystrophy.
2022
Raman Bahal, S P Pradeep, Jose E Manautou, V Kasina, A P Laddha, S E Zakeri
Research Type: Journal Article

Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
2022
Sunna Liu, xiaobo zhong, Sreenidhi Nair, Theodore Rasmussen, Anna Liu, Anagha Gogate, Raman Bahal, Julia M Migliorati, Jose E Manautou
Research Type: Journal Article

Alterations of cytochrome P450-mediated drug metabolism during liver repair and regeneration after acetaminophen-induced liver injury in mice
2022
Yifan Bao, Xiaochao Ma, Jose E Manautou, Mi Phan, Junjie Zhu, xiaobo zhong
Research Type: Journal Article

Multidrug resistance-associated protein 4 (Mrp4) is a novel genetic factor in the pathogenesis of obesity and diabetes.
2021
J D Schuetz, Ajay Chowdary Donepudi, Ji-Young Lee, Young June Lee, Jose E Manautou
Research Type: Journal Article

The growth of siRNA-based therapeutics: Updated clinical studies
2021
May Zhang, xiaobo zhong, Raman Bahal, Theodore Rasmussen, Jose E Manautou
Research Type: Journal Article

lnc-RHL, a novel long non-coding RNA required for the differentiation of hepatocytes from human bipotent progenitor cells.
2021
W He, Theodore Rasmussen, B Prabhakar, Jose E Manautou, A Bochanis, S Lee
Research Type: Journal Article

Emerging Therapeutic Modalities against COVID-19
2020
Raman Bahal, Jose E Manautou, Anisha Gupta, xiaobo zhong, Shipra Malik, Theodore Rasmussen
Research Type: Journal Article

Knockdown of Long Noncoding RNAs Hepatocyte Nuclear Factor 1α Antisense RNA 1 and Hepatocyte Nuclear Factor 4α Antisense RNA 1 Alters Susceptibility of Acetaminophen-Induced Cytotoxicity in HepaRG Cells
2020
Liming Chen, Jose E Manautou, Xiao-bo Zhong, Pei Wang
Research Type: Journal Article

Lack of Multidrug Resistance-associated Protein 4 Prolongs Partial Hepatectomy-induced Hepatic Steatosis
2020
Ji Young Lee, Marisa Pfohl, Steven J. Toro, Ajay Chowdary Donepudi, Jose E Manautou, Angela L. Slitt, Gregory J. Smith, John D. Schuetz, Oladimeji Aladelokun, Li Wang, Yoojin Lee
Research Type: Journal Article

Knockdown of long noncoding RNAs hepatocyte nuclear factor 1a antisense RNA 1 and hepatocyte nuclear factor 4a antisense RNA 1 alters susceptibility of acetaminophen-induced cytotoxicity in HepaRG cells
2020
Jose E Manautou, Pei Wang, Xiao Bo Zhong, Liming Chen
Research Type: Journal Article

Acetaminophen-induced liver injury alters expression and activities of cytochrome P450 enzymes in an age-dependent manner in mouse liver
2020
Lirong Zhang, Jose E Manautou, Junjie Zhu, Xiao Bo Zhong, Jian Shi, Xiaochao Ma, Pei Wang, Xueyan Shao, Yifan Bao, Jingcheng Xiao, Hao Jie Zhu
Research Type: Journal Article

The modulation of transcriptional expression and inhibition of multidrug resistance associated protein 4 (MRP4) by analgesics and their primary metabolites
2020
Jose E Manautou, Carolina I. Ghanem, Renato J. Scialis
Research Type: Journal Article

The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps.
2020
V L Sutherland, D Gulezian, A Wilson, C Cerniglia, S Forry, C A McQueen, R Dietert, S Foley, H Young, S Khare, D Tweedie, A V Alekseyenko, D Mendrick, Chi-ming Chen, F Burns, Jose E Manautou, X Liang
Research Type: Journal Article

Acetaminophen-Induced Liver Injury Alters Expression and Activitiesof Cytochrome P450 Enzymes in an Age-Dependent Manner in Mouse Liver
2020
Jingcheng Xiao, Pei Wang, Lirong Zhang, Jose E Manautou, Jian Shi, Junjie Zhu, Xiaochao Ma, Yifan Bao, Hao-jie Zhu, Xiao-bo Zhong, Xueyan Shao
Research Type: Journal Article

Development of precision medicine approaches based on inter-individual variability of BCRP/ABCG2
2019
xiaobo zhong, Jose E Manautou, Liming Chen, Theodore Rasmussen
Research Type: Journal Article

Identification and characterization of efflux transporters that modulate the subtoxic disposition of diclofenac and its metabolites
2019
Curtis D. Klaassen, Iván L. Csanaky, Jose E Manautou, Lauren M. Aleksunes, Renato J. Scialis
Research Type: Journal Article