Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Scholarly Contributions

186 Scholarly Contributions

118
Poster/Presentations
59
Journal Articles
8
Other Scholarly Works
1
Book Chapter
Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity
2019
Jose E Manautou, Michael J. Goedken, John D. Schuetz, Ajay Chowdary Donepudi
Research Type: Journal Article

Acute acetaminophen intoxication induces direct neurotoxicity in rats manifested as astrogliosis and decreased dopaminergic markers in brain areas associated with locomotor regulation
2019
Fernanda De Fino, Sonia A. Martínez, Carolina I. Ghanem, Jose E Manautou, María Belén Vigo, Veronica Bisagno, Gimena Gómez, María Julia Pérez, Alejandra Scazziota, María Beatriz Di Carlo
Research Type: Journal Article

Ontogenic mRNA expression of RNA modification writers, erasers, and readers in mouse liver.
2019
Jose E Manautou, Li Chen, Raman Bahal, xiaobo zhong, P Wang
Research Type: Journal Article

Modulation of Hepatic MRP3/ABCC3 by Xenobiotics and Pathophysiological Conditions: Role in Drug Pharmacokinetics
2018
Carolina I Ghanem, Jose E Manautou
Research Type: Journal Article

Histone deacetylase 9 plays a role in the anti-fibrogenic effect of astaxanthin in hepatic stellate cells
2017
Yue Yang, Ji-Young Lee, Tho X Pham, Yoojin Lee, Young-Ki Park, Jose E Manautou, Minkyung Bae, Ellen Harness, S Rudraiah, Sung Koo
Research Type: Journal Article

Gender-specific expression of ATP-binding cassette (Abc) transporters and cytoprotective genes in mouse choroid plexus.
2017
Jose E Manautou, K Flores, James L Renfro
Research Type: Journal Article

Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice.
2016
J A Cichocki, G J Smith, S E Jordt, Jose E Manautou, John B Morris, B J Doughty
Research Type: Journal Article

Reduced in vivo toxicity of doxorubicin by encapsulation in cholesterol-containing self-assembled nanoparticles.
2016
L H Mahajan, L Gonzalez-Fajardo, Rajeswari Kasi, B T Liang, D Hargrove, Ming-Hui Chen, D Ndaya, Xiuling Lu, Jose E Manautou
Research Type: Journal Article

Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses.
2016
D W Ferreira, F Galland, P Naquet, L Chasson, M J Goedken, S Rommelaere, Jose E Manautou
Research Type: Journal Article

From hepatoprotection models to new therapeutic modalities for treating liver diseases: a personal perspective.
2016
S Rudraiah, Jose E Manautou
Research Type: Journal Article

Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity.
2016
Jose E Manautou, C I Ghanem, M J Pérez, A D Mottino
Research Type: Journal Article

Acetaminophen Attenuates House Dust Mite-Induced Allergic Airway Disease in Mice.
2016
G J Smith, R S Thrall, Jose E Manautou, John B Morris, M M Cloutier
Research Type: Journal Article

Astaxanthin prevents and reverses the activation of hepatic stellate cells via the modulation of histone deacetylase 9
2016
Young-Ki Park, Ji-Young Lee, Tho X Pham, Sung Koo, S Rudraiah, Jose E Manautou, Minkyung Bae, Yoojin Lee, Yue Yang
Research Type: Journal Article

The antitripanocide benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2).
2016
C I Ghanem, M L Ruiz, Jose E Manautou, J P Rigalli, N Ciriaci, M T Ronco, D E Francés, V A Catania, A M Bataille, V G Perdomo
Research Type: Journal Article

Elucidation of the Mechanisms through Which the Reactive Metabolite Diclofenac Acyl Glucuronide Can Mediate Toxicity.
2016
R J Scialis, Jose E Manautou
Research Type: Journal Article

Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet.
2016
T N Sapper, Richard Bruno, M V Moller, K E Schill, J Li, Jose E Manautou, P R Rohrer, C Chitchumroonchokchai, S Rudraiah, E Mah, J D McDonald
Research Type: Journal Article

Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells.
2016
S Rudraiah, R N Hines, Xinsheng Gu, Jose E Manautou
Research Type: Journal Article

Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.
2015
R P Erickson, Jose E Manautou, R N Hardwick, S A Xanthakos, S N Campion, D W Ferreira, A M Bataille, M D Merrell, N J Cherrington, M J Canet, H Hesham A-Kader
Research Type: Journal Article

Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice.
2015
Jose E Manautou, M J Goedken, S Rudraiah, M B Vigo, C I Ghanem, A M Bataille
Research Type: Journal Article

Antioxidant fractions of Khaya grandifoliola C.DC. and Entada africana Guill. et Perr. induce nuclear translocation of Nrf2 in HC-04 cells.
2015
B Bradley, P Fewou Moundipa, J Njikam Manjia, R Fouemene Tsayem, S Rudraiah, F N Njayou, A M Amougou, Jose E Manautou
Research Type: Journal Article