Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Lack of Multidrug Resistance-associated Protein 4 Prolongs Partial Hepatectomy-induced Hepatic Steatosis
2020
Ji Young Lee, Marisa Pfohl, Steven J. Toro, Ajay Chowdary Donepudi, Jose E Manautou, Angela L. Slitt, Gregory J. Smith, John D. Schuetz, Oladimeji Aladelokun, Li Wang, Yoojin Lee
Research Type: Journal Article

Knockdown of long noncoding RNAs hepatocyte nuclear factor 1a antisense RNA 1 and hepatocyte nuclear factor 4a antisense RNA 1 alters susceptibility of acetaminophen-induced cytotoxicity in HepaRG cells
2020
Jose E Manautou, Pei Wang, Xiao Bo Zhong, Liming Chen
Research Type: Journal Article

Acetaminophen-induced liver injury alters expression and activities of cytochrome P450 enzymes in an age-dependent manner in mouse liver
2020
Lirong Zhang, Jose E Manautou, Junjie Zhu, Xiao Bo Zhong, Jian Shi, Xiaochao Ma, Pei Wang, Xueyan Shao, Yifan Bao, Jingcheng Xiao, Hao Jie Zhu
Research Type: Journal Article

The modulation of transcriptional expression and inhibition of multidrug resistance associated protein 4 (MRP4) by analgesics and their primary metabolites
2020
Jose E Manautou, Carolina I. Ghanem, Renato J. Scialis
Research Type: Journal Article

The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps.
2020
V L Sutherland, D Gulezian, A Wilson, C Cerniglia, S Forry, C A McQueen, R Dietert, S Foley, H Young, S Khare, D Tweedie, A V Alekseyenko, D Mendrick, Chi-ming Chen, F Burns, Jose E Manautou, X Liang
Research Type: Journal Article

Acetaminophen-Induced Liver Injury Alters Expression and Activitiesof Cytochrome P450 Enzymes in an Age-Dependent Manner in Mouse Liver
2020
Jingcheng Xiao, Pei Wang, Lirong Zhang, Jose E Manautou, Jian Shi, Junjie Zhu, Xiaochao Ma, Yifan Bao, Hao-jie Zhu, Xiao-bo Zhong, Xueyan Shao
Research Type: Journal Article

Multidrug resistance-associated protein 4 (Mrp4) expression and its relationship to obesity and diabetes
2020
Jose E Manautou
Research Type: Poster/Presentation

A lesser-known complication of COVID-19 disease: Liver dysfunction
2020
Jose E Manautou
Research Type: Poster/Presentation

The Role of Bromodomain and Extra-Terminal (BET) Proteins on APAP-Induced Hepatotoxicity
2020
Gregory Sartor, Raymond Xue, Ajay Chowdary Donepudi, Steven Toro, Mandakini Singh, Saren M Smith, Jose E Manautou
Research Type: Poster/Presentation

Multidrug Resistance-Associated Protein 4 (Mrp4) Is a Novel Genetic Factor in the Pathogenesis of Obesity and Diabetes
2020
Ajay Chowdary Donepudi, John D Schuetz, Ji-Young Lee, Jose E Manautou
Research Type: Poster/Presentation

Conferencia de Cierre: Evidencia emergente de daño hepatico como secuela de COVID-19
2020
Jose E Manautou
Research Type: Poster/Presentation

Development of precision medicine approaches based on inter-individual variability of BCRP/ABCG2
2019
xiaobo zhong, Jose E Manautou, Liming Chen, Theodore Rasmussen
Research Type: Journal Article

Identification and characterization of efflux transporters that modulate the subtoxic disposition of diclofenac and its metabolites
2019
Curtis D. Klaassen, Iván L. Csanaky, Jose E Manautou, Lauren M. Aleksunes, Renato J. Scialis
Research Type: Journal Article

Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity
2019
Jose E Manautou, Michael J. Goedken, John D. Schuetz, Ajay Chowdary Donepudi
Research Type: Journal Article

Acute acetaminophen intoxication induces direct neurotoxicity in rats manifested as astrogliosis and decreased dopaminergic markers in brain areas associated with locomotor regulation
2019
Fernanda De Fino, Sonia A. Martínez, Carolina I. Ghanem, Jose E Manautou, María Belén Vigo, Veronica Bisagno, Gimena Gómez, María Julia Pérez, Alejandra Scazziota, María Beatriz Di Carlo
Research Type: Journal Article

Ontogenic mRNA expression of RNA modification writers, erasers, and readers in mouse liver.
2019
Jose E Manautou, Li Chen, Raman Bahal, xiaobo zhong, P Wang
Research Type: Journal Article

The Role of Drug Transporters on Hepatic Compensatory Tissue Proliferation and Non-Alcoholic Liver Disease
2019
Jose E Manautou
Research Type: Poster/Presentation

Multidrug resistance protein 4 (Mrp4) regulates nutrient and energy metabolism by altering the adipose tissue physiology
2019
John D Schuetz, Ajay Chowdary Donepudi, Yoojin Yoojin, Jose E Manautou, Ji-Young Lee
Research Type: Poster/Presentation

The GRC Power Hour
2019
Jose E Manautou
Research Type: Poster/Presentation

Academic Leader, Mentor and Researcher in Drug-Induced Hepatotoxicity: Maintaining a Balance for Success
2019
Jose E Manautou
Research Type: Poster/Presentation