Jose E. Manautou
Professor & Department Head/Pharmaceutical Science

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Utilization of System Genomics in the Identification of Genetic Determinants of Adaptation to Chemical Liver Injury
2014
Jose E Manautou
Research Type: Poster/Presentation

Flavin-containing Monooxygenase-3 and Vanin-1: Two Novel Genetic Determinants of Acetaminophen Hepatotoxicity
2014
Jose E Manautou
Research Type: Poster/Presentation

Transcriptional Regulation of Brain ABC Transporters during Acute Acetaminophen (APAP) Intoxication in Mice and the Possible Role of the Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)
2014
Gahnem I Carolina, Jose E Manautou, Rudraiah S Swetha
Research Type: Poster/Presentation

Tolerance to Acetaminophen Hepatotoxicity in the mOuse Model of Acetaminophen Hepatoprotection is Associated with Induction of Flavin-Contaning Monooxygenase-3 (FMO3) in Hepatocytes
2013
Swetha Rudraiah, Theodore P Rasmussen, Igor Gurevich, Jose E Manautou
Research Type: Poster/Presentation

Differences in mRNA and Protein Expression of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) and Nrf2-Dependent Genes
2013
Jose E Manautou, Philip Rohrer
Research Type: Poster/Presentation

Analysis of Changes in Hepatic Gene Expression in a Murine Model of Resistance to Acetaminophen Hepatotoxicity
2013
Jose E Manautou
Research Type: Poster/Presentation

Genomic Identification of Novel Pathways that Confer Resistance to Chemical Induced-Liver Injury: Validation Using Cellular and Transgenic Models
2013
Jose E Manautou
Research Type: Poster/Presentation

Acetaminophen Produces Oxidative Stress in the Airways and Modulates Respiratory Responses to Oxidant Challenge
2013
Joseph A Cichocki, Jose E Manautou, John B Morris, Gregory J Smith
Research Type: Poster/Presentation

Role of Vanin-1 in acetaminophen hepatotoxicity: Regulation of thiol homeostasis and immune response to liver injury
2013
Jose E Manautou
Research Type: Poster/Presentation

Vanin-1 Knockout Mice Exhibit Alterations in Compensatory Immune Infiltration and Hepatocyte Proliferation following Acetaminophen Toxicity
2013
Philippe Naquet, Daniel W Ferreira, Franck Gallard, Jose E Manautou
Research Type: Poster/Presentation

Hepatic Transporters and Development on Tolerance to Hepatotoxicity by Acetaminophen
2013
Jose E Manautou
Research Type: Poster/Presentation

Hepatic Flavin-Containing Monooxygenase-3 (FMO3) Protein Is Inducible by Acetaminophen Treatment
2013
Jose E Manautou, Swetha A Rudraiah
Research Type: Poster/Presentation

Mechanistic Role(s) of Cytochrome(s) P450 in Oxidative Stress and Inflammation: New Opportunities for Drug Discovery
2013
Jose E Manautou, Bhagavatula Moorthy
Research Type: Poster/Presentation

Acetaminophen at low doses depletes airway glutathione and alters respiratory reflex responses
2013
John B Morris, Joseph A Cichicki, Jose E Manautou, Gregory J Smith
Research Type: Poster/Presentation

The ABC’s of Acetaminophen Toxicity
2013
Jose E Manautou
Research Type: Poster/Presentation

Suppressive Effect of HES1 (Drosophila Hairy and Enhancer of Split-1) on Human Hepatic Multidrug Resistance-Associated Protein 4 (MRP4) Gene Expression and Induction of HES1 by Oxidative Stress
2013
Xinsheng Gu, Jose E Manautou
Research Type: Poster/Presentation

Role of Vanin-1 in acetaminophen hepatotoxicity: regulation of thiol homeostasis and immune response to liver injury
2013
Jose E Manautou
Research Type: Poster/Presentation

Proteina de Resistencia a Multidrogas 4 (MRP4, ABCC4) Como un Factor Potencial de Resistencia a la Toxicidad Provocada por Acetaminofeno
2013
Jose E Manautou
Research Type: Poster/Presentation

Modification in the Expression of Brain ABC Transporters During Acute Acetaminophen Intoxication In Mice
2013
Gahnem I Carolina, Rudraiah S Swetha, Jose E Manautou
Research Type: Poster/Presentation

The role of multi-drug resistance protein 4 (Mrp4, Abcc4) in protecting against acetaminophen (APAP)-induced hepatotoxicity
2012
Amy M Bataille, Jose E Manautou
Research Type: Poster/Presentation