Xiaobo Zhong
Professor/Pharmaceutical Science

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Molecular mechanisms of ADME of nucleic acid drugs
2022
xiaobo zhong
Research Type: Poster/Presentation

Mutations in muscle-type creatine kinase impact HIV prevention
2022
Julia M Migliorati, xiaobo zhong
Research Type: Journal Article

Nedosiran, a candidate siRNA drug for the treatment of primary hyperoxaluria: design, development, and clinical studies.
2022
Jose E Manaoutou, Jenny Zhao, Anna Liu, Sherouk M Tawfik, Julia M Migliorati, xiaobo zhong, Milan Shah, Raman Bahal, Theodore P Rasmussen
Research Type: Journal Article

Neonatal Phenobarbital Exposure Results in Decreased Proton Pump Inhibition by Omeprazole in Adult Mouse
Yun-Chen Tien, Chad Pope, xiaobo zhong, Stephanie Piekos
Research Type: Conference Proceedings

Neonatal phenobarbital exposure with loading dose for seizures results in rapid P450 metabolizers in adult liv
2015
Chad Pope, xiaobo zhong, Yun-chen Tien, Xiaochao Ma, Ke Liu
Research Type: Poster/Presentation

Nephrotoxicity of marketed antisense oligonucleotide drugs
2022
Feryal Alhamadani, Rajvi Parikh, Theodore Rasmussen, Evan M McCabe, SooWan Lee, Xiaobo Zhong, Jose E Manautou, Aniket Wahane, Hangyu Wu, Raman Bahal, Kristy Zhang
Research Type: Journal Article

Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche
2012
Craig Semerad, Jeffrey S Huang, Linheng Li, Ryohichi Sugimura, Andrew Box, Toshio Suda, Fumio Arai, Aparna Venkatraman, xiaobo zhong, Lai Peng, Xi C He
Research Type: Journal Article

Novel aspects of long non-coding RNAs in regulation of P450 genes
2012
xiaobo zhong
Research Type: Poster/Presentation

Ontogenic mRNA expression of RNA modification writers, erasers, and readers in mouse liver.
2019
Jose E Manautou, Li Chen, Raman Bahal, xiaobo zhong, P Wang
Research Type: Journal Article

Ontogenic profiling of the nuclear receptor superfamily in mouse liver using RNA-Seq
2012
xiaobo zhong, Curtis D Klaassen, Sumedha S Gunewardena, Helen J Renaud, Hong Lu, Byunggil Yoo, Lai Peng, Julia Y Cui, Jie Liu
Research Type: Poster/Presentation

Ontogeny of energy metabolism genes in mice
2013
Hong Lu, Curtis D Klaassen, xiaobo zhong, Helen J Renaud, Julia Yue Cui
Research Type: Poster/Presentation

Ontogeny of hepatic energy metabolism genes in mice as revealed by RNA-sequencing.
2014
Curtis D Klaassen, Yue Julia Cui, Hong Lu, Helen J Renaud, xiaobo zhong
Research Type: Journal Article

Phenobarbital increased hepatic toxicity of acetaminophen due to cytochrome P450 induction in young and adult mice
2019
Pei Wang, Yifan Bao, Liming Chen, xiaobo zhong, Xueyan Shao
Research Type: Poster/Presentation

Phenobarbital treatment at a neonatal age results in decreased efficacy of omeprazole in adult mice
2017
Yun-Chen Tien, Stephanie C Piekos, xiaobo zhong, Chad Pope
Research Type: Journal Article

Potential role of epigenetic mechanisms in the regulation of drug metabolism and transport
2013
Yoichi Osawa, Ai-ming Yu, Sundheer Beedanagari, xiaobo zhong, Oliver Hankinson, Magnus Ingelman-Sundberg, Lai Peng
Research Type: Journal Article

RNA sequencing reveals dynamic changes of mRNA abundance of cytochromes P450 and their alternative transcripts during mouse liver development
2012
Hong Lu, Curtis D Klaassen, Sumedha Gunewardena, xiaobo zhong, Byunggil Yoo, Lai Peng
Research Type: Journal Article

RNA-Seq provides new insights on the relative mRNA abundance of antioxidant components during mouse liver development
2019
Curtis D Klaassen, Kai Connie Wu, xiaobo zhong, Julia Yue Cui, Hong Lu
Research Type: Journal Article

RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development
2012
Jie Liu, Hong Lu, Helen J Renaud, Curtis K Klaassen, xiaobo zhong, Sumedha S Gunewardena, Byunggil Yoo, Julia Y Cui
Research Type: Journal Article

RNA-Seq reveals transcriptional response of coding RNAs and long non-coding RNAs to rifampicin treatment in primary human hepatocytes and HepaRG cells
2013
Chad Pope, xiaobo zhong
Research Type: Poster/Presentation

RNA-Sequencing Quantification of Hepatic Ontogeny and Tissue Distribution of mRNAs of Phase II Enzymes in Mice.
2013
xiaobo zhong, Hong Lu, Julia Y Cui, Sumedha Gunewardena, Byunggil Yoo, Curtis D Klaassen
Research Type: Journal Article