Xiaobo Zhong
Professor/Pharmaceutical Science
Storrs Mansfield
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Scholarly Contributions
138 Scholarly Contributions
Impact on acetaminophen-induced hepatotoxicity by long non-coding RNAs HNF1-AS1 and HNF4-AS1 in HepaRG cells
2019
Research Type: Poster/Presentation
Alterations of expression and functions of drug metabolizing P450 enzymes in injured liver induced by acetaminophen in mice at different ages
2019
Research Type: Poster/Presentation
Phenobarbital increased hepatic toxicity of acetaminophen due to cytochrome P450 induction in young and adult mice
2019
Research Type: Poster/Presentation
Knockdown of Long Noncoding RNAs Hepatocyte Nuclear Factor 1α Antisense RNA 1 and Hepatocyte Nuclear Factor 4α Antisense RNA 1 Alters Susceptibility of Acetaminophen-Induced Cytotoxicity in HepaRG Cells
2020
Research Type: Journal Article
The roles of long noncoding RNAs HNF1α-AS1 and HNF4α-AS1 in drug metabolism and human diseases
2020
Research Type: Journal Article
Impact of obese levels on the hepatic expression of drug-processing genes in adult and offspring mice
2020
Research Type: Journal Article
Acetaminophen-Induced Liver Injury Alters Expression and Activitiesof Cytochrome P450 Enzymes in an Age-Dependent Manner in Mouse Liver
2020
Research Type: Journal Article
Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced Steatosis
2020
Research Type: Journal Article
Acute drug-induced liver injury with medications used in the COVID-19 pandemic.
2020
Research Type: Poster/Presentation
Alterations of drug metabolism and therapeutic efficacy during liver recovery and regeneration after acetaminophen-induced liver injury.
2020
Research Type: Poster/Presentation
Histone 3 lysine 9 methylating enzyme G9a is involved in transcriptional regulation of expression of nuclear receptors and cytochrome P450 genes in HepaRG cells.
2020
Research Type: Poster/Presentation
The Long Non-coding RNA HNF4A-AS1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications
2021
Research Type: Journal Article
The growth of siRNA-based therapeutics: Updated clinical studies
2021
Research Type: Journal Article
Short and long-term alterations of ADME for drug efficacy and toxicity by drug treatment at neonatal and infant ages in preclinical species.
2021
Research Type: Poster/Presentation
An injured liver caused by overdose of acetaminophen has altered expression and activities of P450 enzymes and associated drug efficacy during liver recovery and regeneration.
2021
Research Type: Poster/Presentation
Alterations of cytochrome P450-mediated drug metabolism and therapeutic efficacy during liver recovery and regeneration after acetaminophen-induced liver injury.
2021
Research Type: Poster/Presentation
Special Section on Drug Metabolism in Liver Injury and Repair - Editorial
2022
Research Type: Journal Article