Xiaobo Zhong
Professor/Pharmaceutical Science

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Scholarly Contributions

138 Scholarly Contributions

78
Journal Articles
52
Poster/Presentations
6
Conference Proceedings
2
Other Scholarly Works
Nedosiran, a candidate siRNA drug for the treatment of primary hyperoxaluria: design, development, and clinical studies.
2022
Jose E Manaoutou, Jenny Zhao, Anna Liu, Sherouk M Tawfik, Julia M Migliorati, xiaobo zhong, Milan Shah, Raman Bahal, Theodore P Rasmussen
Research Type: Journal Article

Special Section on Bile Acids, Drug Metabolism, and Toxicity—Editorial
2022
Yurong Lai, xiaobo zhong
Research Type: Journal Article

Mutations in muscle-type creatine kinase impact HIV prevention
2022
Julia M Migliorati, xiaobo zhong
Research Type: Journal Article

Adverse Drug Reactions and Toxicity of the Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
2022
Kristy Zhang, Hangyu Wu, Rajvi Parikh, xiaobo zhong, Theodore Rasmussen, Feryal Alhamadani, Jose E Manautou, Raman Bahal
Research Type: Journal Article

Long noncoding RNAs hepatocyte nuclear factor 1A antisense RNA 1 and hepatocyte nuclear factor 4A antisense RNA 1 are involved in ritonavir-induced cytotoxicity through histone modifications in hepatoma cells
2022
Kun Yang, Yihang Yu, Liang Yan, Lirong Zhang, Yiting Wang, Pei Wang, xiaobo zhong, Xiaofei Wang
Research Type: Journal Article

Alterations of cytochrome P450-mediated drug metabolism during liver repair and regeneration after acetaminophen-induced liver injury in mice
2022
Yifan Bao, Xiaochao Ma, Jose E Manautou, Mi Phan, Junjie Zhu, xiaobo zhong
Research Type: Journal Article

Special section on drug metabolism and regulation – Editorial
2022
xiaobo zhong, Yurong Lai
Research Type: Journal Article

Simultaneous targeting of multiple oncomiRs with phosphorothioate or PNA-based anti-miRs in lymphoma cell lines
2022
Raman Bahal, Karishma Dhuri, Xiaobo Zhong, Sai Pallavi Pradeep, Frank J Slack, Jason Shi, Anisha Gupta, Eleni Anastasiadou
Research Type: Journal Article

siRNA drug Leqvio (inclisiran) to lower cholesterol
2022
Julia M Migliorati, xiaobo zhong, Jing Jin
Research Type: Journal Article

Special section on Pharmacokinetics and ADME of biological therapeutics - Editorial
2022
Yurong Lai, xiaobo zhong
Research Type: Journal Article

Targeting liver with nucleic acid therapeutics for the treatment of liver-originated systemic diseases
2022
xiaobo zhong
Research Type: Poster/Presentation

Absorption, distribution, metabolism, and excretion of the FDA-approved antisense oligonucleotide drugs
2022
xiaobo zhong
Research Type: Poster/Presentation

Molecular mechanisms of ADME of nucleic acid drugs
2022
xiaobo zhong
Research Type: Poster/Presentation

Roles of lncRNAs HNF1A-AS1 and HNF4A-AS1 in drug metabolism and drug-induced toxicity.
2022
xiaobo zhong
Research Type: Poster/Presentation

The Long Non-coding RNA HNF4A-AS1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications
2021
Yiting Wang, Kun Yang, Xiaofei Wang, Pei Wang, Lirong Zhang, Shitong Chen, Liang Yan, xiaobo zhong, Shengna Han
Research Type: Journal Article

The growth of siRNA-based therapeutics: Updated clinical studies
2021
May Zhang, xiaobo zhong, Raman Bahal, Theodore Rasmussen, Jose E Manautou
Research Type: Journal Article

Short and long-term alterations of ADME for drug efficacy and toxicity by drug treatment at neonatal and infant ages in preclinical species.
2021
xiaobo zhong
Research Type: Poster/Presentation

An injured liver caused by overdose of acetaminophen has altered expression and activities of P450 enzymes and associated drug efficacy during liver recovery and regeneration.
2021
xiaobo zhong
Research Type: Poster/Presentation

Alterations of cytochrome P450-mediated drug metabolism and therapeutic efficacy during liver recovery and regeneration after acetaminophen-induced liver injury.
2021
xiaobo zhong
Research Type: Poster/Presentation

Knockdown of Long Noncoding RNAs Hepatocyte Nuclear Factor 1α Antisense RNA 1 and Hepatocyte Nuclear Factor 4α Antisense RNA 1 Alters Susceptibility of Acetaminophen-Induced Cytotoxicity in HepaRG Cells
2020
Liming Chen, Jose E Manautou, Xiao-bo Zhong, Pei Wang
Research Type: Journal Article