Ashis K. Basu
Professor/Chemistry

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Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2′-Deoxyguanosin-8-yl)-3-aminobenzanthrone Adduct by Human DNA Polymerase η
2016
Amritraj Patra, Zucai Suo, Arindom Chatterjee, Martin Egli, Michael P. Stone, E. John Tokarsky, Dustin A. Politica, Ashis K Basu
Research Type: Journal Article

Comparative Error-Free and Error-Prone Translesion Synthesis of N 2-2′-Deoxyguanosine Adducts Formed by Mitomycin C and Its Metabolite, 2, 7-Diaminomitosene, in Human Cells
2016
Paritosh Pande, Elise Champeil, Ashis K Basu, Chaitra Surugihalli, Arindam Bose
Research Type: Journal Article

Pre-steady-state kinetic investigation of bypass of a bulky guanine lesion by human Y-family DNA polymerases
2016
E. John Tokarsky, Zucai Suo, Chanchal K. Malik, Ashis K Basu, Varun V. Gadkari, Walter J. Zahurancik
Research Type: Journal Article

Translesion Synthesis of the N2-2′-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1
2016
Ashis K Basu, Amy D. Millsap, Arindam Bose, Carmelo J. Rizzo, Arnie DeLeon
Research Type: Journal Article

Why some chemicals cause cancer?
2016
Ashis K Basu
Research Type: Poster/Presentation

Synthesis and Replication Properties of a DNA-Protein Cross-link
2016
Ashis K Basu
Research Type: Poster/Presentation

DNA Damage and Mutagenesis: Research in Toxicology at the Interface of Chemistry and Biology
2016
Ashis K Basu
Research Type: Poster/Presentation

Base-Displaced Intercalated Structure of the N-(2′-Deoxyguanosin-8-yl)-3-aminobenzanthrone DNA Adduct
2015
Michael P Stone, Ashis K Basu, Chanchal K Malik, Dustin A Politica
Research Type: Journal Article

DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8–2′-deoxyguanosine adduct of the dietary mutagen IQ in human cells!!!
2015
Paritosh Pande, Carmelo J Rizzo, Arindam Bose, Edward K Hawkins, Amy D Millsap, Ashis K Basu, Vijay P Jasti
Research Type: Journal Article

Unlike catalyzing error-free bypass of 8-oxodGuo, DNA polymerase λ is responsible for a significant part of Fapy·dG-induced G → T mutations in human cells.
2015
Ashis K Basu, P Pande, K Haraguchi, Y L Jiang, M M Greenberg
Research Type: Journal Article

Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitrosamine-derived O 2-alkylthymidines in human cells
2015
Arindam Bose, Vijay P Jasti, Savithri Weerasooriya, Ashis K Basu, Thomas E Spratt
Research Type: Journal Article

Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase
2015
Georgia Efthimiopoulos, E John Tokarsky, Zucai Suo, Chanchal K Malik, Ashis K Basu, Rajan Vyas
Research Type: Journal Article

Biological relevance of oxidative debris present in as-prepared graphene oxide.
2015
Ashis K Basu, P Pande, A Pattammattel, W G Tsui, C L Williams, Challa V Kumar
Research Type: Journal Article

Biological relevance of oxidative debris present in as-prepared graphene oxide
2015
Ashis K Basu, Christina L Williams, Ajith Pattammattel, Challa Vijaya Kumar, William G Tsui, Paritosh Pande
Research Type: Journal Article

Mutagenicity of C8-Guanine Adduct Formed by 3-Nitrobenzanthrone in Human Cells
2015
Ashis K Basu
Research Type: Poster/Presentation

Synthesis and Characterization of 2'-Deoxyguanosine Adducts of the Cancer-Causing Agents, 1-Nitropyrene and 6-Nitrochrysene
2015
Ashis K Basu
Research Type: Poster/Presentation

Translesion Synthesis of the C8-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells
2015
Ashis K Basu
Research Type: Poster/Presentation

Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replication of (5'S)-8,5'-cyclopurine-2'-deoxynucleosides in vitro by DNA polymerase IV, exo-free Klenow fragment, and Dpo4.
2014
V Pednekar, S Weerasooriya, Ashis K Basu, V P Jasti
Research Type: Journal Article

Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase.
2014
C K Malik, V V Gadkari, Z Suo, E J Tokarsky, Ashis K Basu
Research Type: Journal Article

Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis.
2014
C K Malik, P Pande, Ashis K Basu, A Bose, V P Jasti
Research Type: Journal Article