Ashis K. Basu
Professor/Chemistry

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Replication inhibition and miscoding properties of DNA templates containing a site-specific cis-thymine glycol or urea residue.
1998
P H Bolton, Ashis K Basu, B Jerkovic, J M McNulty
Research Type: Journal Article

Nuclear magnetic resonance solution structures of covalent aromatic amine-DNA adducts and their mutagenic relevance.
1998
Zheyin (jane) Gu, D J Patel, S Broyde, B E Hingerty, Ashis K Basu, Amy Gorin, B Mao
Research Type: Journal Article

Sequence specific mutagenesis of the major (+)-anti-benzo[a]pyrene diol epoxide-DNA adduct at a mutational hot spot in vitro and in Escherichia coli cells.
1997
E L Loechler, Ashis K Basu, N E Geacintov, R R Vyas, C J Hanrahan, M D Bacolod, T Liu
Research Type: Journal Article

Solution conformation of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dC in a DNA duplex.
1996
B Mao, B E Hingerty, S Broyde, D J Patel, Ashis K Basu, R R Vyas
Research Type: Journal Article

Solution properties and computational analysis of an oligodeoxynucleotide containing N-(deoxyguanosin-8-yl)-1-aminopyrene.
1996
B E Hingerty, R Shapiro, S Broyde, Ashis K Basu, R R Vyas, S Ellis, S J Nolan
Research Type: Journal Article

Site-specific frame-shift mutagenesis by the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-y1)-1-aminopyrene located in the (CG)3 sequence: effects of SOS, proofreading, and mismatch repair.
1996
R R Vyas, Ashis K Basu, S A Malia
Research Type: Journal Article

Mutagenic specificity of reductively activated 1-nitropyrene in Escherichia coli.
1995
Ashis K Basu, S A Malia
Research Type: Journal Article

DNA polymerase action on an oligonucleotide containing a site-specifically located N-(deoxyguanosin-8-yl)-1-aminopyrene.
1995
Ashis K Basu, R R Vyas
Research Type: Journal Article

Reductive metabolism of 1-nitropyrene accompanies deamination of cytosine.
1994
Ashis K Basu, S A Malia
Research Type: Journal Article

Effect of site-specifically located mitomycin C-DNA monoadducts on in vitro DNA synthesis by DNA polymerases.
1993
M Tomasz, S A Malia, Ashis K Basu, R Bizanek, Sneha Kumar, C J Hanrahan
Research Type: Journal Article

Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole.
1993
Ashis K Basu, L J Niedernhofer, J M Essigmann, L A Ramos, M L Wood
Research Type: Journal Article

Both purified human 1,N6-ethenoadenine-binding protein and purified human 3-methyladenine-DNA glycosylase act on 1,N6-ethenoadenine and 3-methyladenine.
1992
J T Ku≈õmierek, B Rydberg, A Antoccia, Z H Qiu, P E Gallagher, Ashis K Basu, M K Dosanjh, B Singer, H Fraenkel-Conrat
Research Type: Journal Article

The role of carcinogen DNA adduct structure in the induction of mutations.
1990
E L Loechler, J M Essigmann, M Benasutti, Ashis K Basu, C L Green
Research Type: Journal Article

Site-specifically alkylated oligodeoxynucleotides: probes for mutagenesis, DNA repair and the structural effects of DNA damage.
1990
J M Essigmann, Ashis K Basu
Research Type: Journal Article

Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase.
1989
T D Connors, E Dogliotti, Ashis K Basu, K S Ellison, J M Essigmann
Research Type: Journal Article

Genetic effects of thymine glycol: site-specific mutagenesis and molecular modeling studies.
1989
Ashis K Basu, S A Leadon, E L Loechler, J M Essigmann
Research Type: Journal Article

Mutagenic specificity of alkylated and oxidized DNA bases as determined by site-specific mutagenesis.
1989
J M Essigmann, E L Loechler, Ashis K Basu
Research Type: Journal Article

O6-alkyldeoxyguanosine detection by 32P-postlabeling and nucleotide chromatographic analysis.
1988
J M Essigmann, V L Wilson, Ashis K Basu, C C Harris, Robert Smith
Research Type: Journal Article

Site-specifically modified oligodeoxynucleotides as probes for the structural and biological effects of DNA-damaging agents.
1988
J M Essigmann, Ashis K Basu
Research Type: Journal Article

Identification of adducts formed by reaction of guanine nucleosides with malondialdehyde and structurally related aldehydes.
1988
Ashis K Basu, K Stone, L J Marnett, S M O'Hara, O Mols, P Valladier
Research Type: Journal Article