Ashis K. Basu
Professor/Chemistry
Storrs Mansfield
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Scholarly Contributions
126 Scholarly Contributions
Repair Efficiency of (5'S)-8,5'-cyclo-2'-deoxyguanosine and (5'S)-8,5'-cyclo-2'-deoxyadenosine Depends on the Complementary Base
2012
Research Type: Poster/Presentation
(5'S)-8,5'-cyclo-2'-deoxyguanosine is a strong block to replication, a potent pol V-dependent mutagenic lesion, and is inefficiently repaired in Escherichia coli.
2011
Research Type: Journal Article
Genetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: DNA polymerases IV and V compete for error-prone bypass.
2011
Research Type: Journal Article
Tobacco-specific nitrosamine-derived O2-alkylthymidines are potent mutagenic lesions in SOS-induced Escherichia coli
2011
Research Type: Journal Article
Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model.
2010
Research Type: Journal Article
Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion site.
2010
Research Type: Journal Article
Replication Past the γ-Radiation-Induced Guanine-Thymine Cross-Link G[8,5-Me]T by Human and Yeast DNA Polymerase η.
2010
Research Type: Journal Article
The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA.
2009
Research Type: Journal Article
Synthesis of oligonucleotides containing 2'-deoxyguanosine adducts of nitropyrenes.
2009
Research Type: Journal Article
Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase.
2009
Research Type: Journal Article
Inhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts.
2008
Research Type: Journal Article
Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA.
2008
Research Type: Journal Article
Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase eta.
2008
Research Type: Journal Article
Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene in mammalian cells.
2007
Research Type: Journal Article
Genetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells.
2006
Research Type: Journal Article
Repair of thymine glycol by hNth1 and hNeil1 is modulated by base pairing and cis-trans epimerization.
2006
Research Type: Journal Article
Specific and efficient binding of xeroderma pigmentosum complementation group A to double-strand/single-strand DNA junctions with 3'- and/or 5'-ssDNA branches.
2006
Research Type: Journal Article