Xiaobo Zhong
Professor/Pharmaceutical Science

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The roles of long noncoding RNAs HNF1α-AS1 and HNF4α-AS1 in drug metabolism and human diseases
2020
Suzhen Jiang, Xiao-bo Zhong, Yifan Bao, Liming Chen
Research Type: Journal Article

Impact of obese levels on the hepatic expression of drug-processing genes in adult and offspring mice
2020
Liming Chen, Xueyan Shao, Lirong Zhang, Xiaochao Ma, Junjie Zhu, Yifan Bao, Pei Wang, Xiao-bo Zhong
Research Type: Journal Article

Acetaminophen-Induced Liver Injury Alters Expression and Activitiesof Cytochrome P450 Enzymes in an Age-Dependent Manner in Mouse Liver
2020
Jingcheng Xiao, Pei Wang, Lirong Zhang, Jose E Manautou, Jian Shi, Junjie Zhu, Xiaochao Ma, Yifan Bao, Hao-jie Zhu, Xiao-bo Zhong, Xueyan Shao
Research Type: Journal Article

Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced Steatosis
2020
Warren W Ku, Parimal Pande, xiaobo zhong
Research Type: Journal Article

Emerging Therapeutic Modalities against COVID-19
2020
Raman Bahal, Jose E Manautou, Anisha Gupta, xiaobo zhong, Shipra Malik, Theodore Rasmussen
Research Type: Journal Article

Acute drug-induced liver injury with medications used in the COVID-19 pandemic.
2020
xiaobo zhong
Research Type: Poster/Presentation

Alterations of drug metabolism and therapeutic efficacy during liver recovery and regeneration after acetaminophen-induced liver injury.
2020
xiaobo zhong
Research Type: Poster/Presentation

Histone 3 lysine 9 methylating enzyme G9a is involved in transcriptional regulation of expression of nuclear receptors and cytochrome P450 genes in HepaRG cells.
2020
xiaobo zhong
Research Type: Poster/Presentation

RNA-Seq provides new insights on the relative mRNA abundance of antioxidant components during mouse liver development
2019
Curtis D Klaassen, Kai Connie Wu, xiaobo zhong, Julia Yue Cui, Hong Lu
Research Type: Journal Article

Epigenetic memory is involved in the persistent alterations of drug metabolism in adult mice due to PCN-activated PXR during early life
2019
Shengna Han, Pei Wang, Lirong May Zhang, Guangming Liu, Yali Nie, xiaobo zhong, Jiangfeng Li
Research Type: Journal Article

Development of precision medicine approaches based on inter-individual variability of BCRP/ABCG2
2019
xiaobo zhong, Jose E Manautou, Liming Chen, Theodore Rasmussen
Research Type: Journal Article

Enzymes and Pathways of Kavain Bioactivation and Biotransformation
2019
Jie Lu, Junjie Zhu, Xiaochao Ma, Amina I Shehu, Xiao-bo Zhong, Pengcheng Wang
Research Type: Journal Article

Ontogenic mRNA expression of RNA modification writers, erasers, and readers in mouse liver.
2019
Jose E Manautou, Li Chen, Raman Bahal, xiaobo zhong, P Wang
Research Type: Journal Article

The HNF1a-Regulated LncRNA HNF1a-AS1 Is Involved in theRegulation of Cytochrome P450 Expression in Human LiverTissues and Huh7 Cells
2019
Yali Nie, Liang Yan, Lirong Zhang, Liming Chen, Jingyang Liu, Guangming Liu, Shitong Chen, Yiting Wang, Weihong Yang, xiaobo zhong, Pei Wang, Shengna Han
Research Type: Journal Article

Impacts on hepatic ontogenic expression of drug-metabolizing enzymes by high-fat diet-induced obesity in mice
2019
Xueyan Shao, Liming Chen, Yifan Bao, Pei Wang, Lirong May Zhang, xiaobo zhong
Research Type: Poster/Presentation

Drug metabolism under drug-induced liver injury
2019
Xiao-bo Zhong
Research Type: Poster/Presentation

Impact on acetaminophen-induced hepatotoxicity by long non-coding RNAs HNF1-AS1 and HNF4-AS1 in HepaRG cells
2019
Jose E Manautou, Liming Chen, Xiao-bo Zhong
Research Type: Poster/Presentation

Alterations of expression and functions of drug metabolizing P450 enzymes in injured liver induced by acetaminophen in mice at different ages
2019
Xiao-bo Zhong, Yifan Bao
Research Type: Poster/Presentation

Phenobarbital increased hepatic toxicity of acetaminophen due to cytochrome P450 induction in young and adult mice
2019
Pei Wang, Yifan Bao, Liming Chen, xiaobo zhong, Xueyan Shao
Research Type: Poster/Presentation

A novel fibroblast growth factor 15 dependent- and bile acid independent-promotion of liver regeneration in mice
2018
xiaobo zhong, Monica D Chow, Xie Wen, Yi-Horng Lee, Bo Kong, Runbin Sun, Grace L Guo, Mingxing Huang
Research Type: Journal Article