Xiaobo Zhong
Professor/Pharmaceutical Science

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A transcriptional regulatory network containing nuclear receptors and lncRNAs controls basal and drug-induced expression of cytochrome P450s in HepaRG cells
2018
Yifan Bao, Stephanie C. Piekos, Lirong Zhang, Kexin Zhu, Liming Chen, xiaobo zhong
Research Type: Journal Article

Liver Metabolomics in a Mouse Model of Erythropoietic Protoporphyria
2018
Pengcheng Wang, xiaobo zhong, Grace L Guo, Sachar Madhav, Jie Lu, Amina I Shehu, Xiaochao Ma
Research Type: Journal Article

Genetic variations associated with anti-tuberculosis drug-induced liver injury
2018
Xiachao Ma, Xiaobo Zhong, Yifan Bao, Theodore P Rasmussen
Research Type: Journal Article

Consequences of phenytoin exposure on hepatic cytochrome P450 expression during postnatal liver maturation in mice
2018
xiaobo zhong, Jian Shi, Pengcheng Wang, Sharon Yaqoob, Liming Chen, Hao-jie Zhu, Xiaochao Ma, Stephanie C Piekos
Research Type: Journal Article

Variability in expression of the human MDR1 drug efflux transporter and genetic variation of the ABCB1 gene: implications for drug-resistant epilepsy
2018
Anna Heinrich, xiaobo zhong, Theodore Rasmussen
Research Type: Other Scholarly Work

Development of precision medicine based on drug metabolism
2018
xiaobo zhong
Research Type: Poster/Presentation

Short and long-term effects of phenytoin exposure on the liver proteome of neonatal and adult mice using SWATH-MS technology
2018
Xinyue Jing, Jian Shi, Liming Chen, Stephanie C Piekos, Haojie Zhu, xiaobo zhong
Research Type: Poster/Presentation

A transcriptional regulatory network containing nuclear receptors and long non-coding RNAs controls basal and induced expression of cytochrome P450s in liver cells
2018
Yifan Bao, Stephanie C Piekos, Liming Chen, xiaobo zhong
Research Type: Poster/Presentation

The role of long non-coding RNAs HNF1a-AS1 and HNF4a-AS1 in the regulation of drug metabolizing cytochrome P450 enzymes and nuclear receptors in liver cells
2018
Liming Chen, Yifan Bao, xiaobo zhong, Stephanie C Piekos
Research Type: Poster/Presentation

Getting bigger: long noncoding RNAs in liver metabolism
2018
xiaobo zhong
Research Type: Poster/Presentation

Control of postnatal liver maturation by nuclear receptors and lncRNAs
2018
xiaobo zhong
Research Type: Poster/Presentation

Epigenetic mechanisms in P450-mediated drug metabolism
2018
xiaobo zhong
Research Type: Poster/Presentation

Strategy for the development of precision medicine based on drug metabolism
2018
xiaobo zhong
Research Type: Poster/Presentation

Alterations of Histone Modifications Contribute to Pregnane X Receptor-mediated Induction of CYP3A4 by Rifampicin
2017
xiaobo zhong, Quancheng Kan, Liang Yan, Jingyang Liu, Yiting Wang, Yali Nie, Lirong Zhang
Research Type: Journal Article

H19 promotes cholestatic liver fibrosis by preventing ZEB1-mediated inhibition of EpCAM
2017
Michele Beaudoin, Chune Liu, xiaobo zhong, Jocelyn Trottier, Linheng Li, Guangyong Peng, Li Wang, Chad Pope, Yongfeng Song, Xia Liu, Li Zhang, Olivier Barbier
Research Type: Journal Article

The Role of H19, a Long Non-coding RNA, in Mouse Liver Postnatal Maturation
2017
Stephanie C Piekos, Liming Chen, Chad Pope, Shashank Mishra, xiaobo zhong
Research Type: Journal Article

Impact of Drug Treatment at Neonatal Ages on Variability of Drug Metabolism and Drug-drug Interactions in Adult Life
2017
xiaobo zhong, Chad Pope, Austin Ferrara, Stephanie Piekos
Research Type: Journal Article

Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21st International Symposium on Microsomes and Drug Oxidations (MDO).
2017
Magnus Ingelman-Sundberg, David J Waxman, Aadra P Bhatt, Matthew R Redinbo, Lauren M Aleksunes, Wen Xie, Hyunyoung Jeong, Pengying Hao, xiaobo zhong, Peter J Turnbaugh, Li Wang, Ai-ming Yu, Nathan J Cherrington, Edward M Morgan, Curtis D Klaassen, Ulrich M Zanger
Research Type: Journal Article

Targeting H19, an imprinted long non-coding RNA, in hepatic functions and liver diseases
2017
xiaobo zhong, Shashank Mishra, Joshua Russell, Qingqing Zhou, Chad Pope
Research Type: Journal Article

Deficiency of N-acetyltransferase increases the interactions of isoniazid with endobiotics in mouse liver
2017
Jie Lu, xiaobo zhong, Pengcheng Wang, Denis M Grant, Xiaochao Ma, Raman Venkataramanan, Amina I Shehu, Rujuta H Joshi, Kim S Sugamori
Research Type: Journal Article